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  • 藤泊它碱

    Tembetarine

    藤泊它碱
    产品编号 CFN95542
    CAS编号 18446-73-6
    分子式 = 分子量 C20H26NO4 = 344.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 The roots of Thalictrum foliolosum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    藤泊它碱 CFN95542 18446-73-6 1mg QQ客服:1457312923
    藤泊它碱 CFN95542 18446-73-6 5mg QQ客服:1457312923
    藤泊它碱 CFN95542 18446-73-6 10mg QQ客服:1457312923
    藤泊它碱 CFN95542 18446-73-6 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Sanford Burnham Medical Research Institute (USA)
  • Uniwersytet Jagielloński w Krakowie (Poland)
  • University of the Basque Country (Spain)
  • Julius Kühn-Institut (Germany)
  • Siksha O Anusandhan University (India)
  • National Research Council of Canada (Canada)
  • Mendel University in Brno (Czech Republic)
  • Instituto Politécnico de Bragan?a (Portugal)
  • University of Pretoria (South Africa)
  • Agricultural Research Organization (ARO) (Israel)
  • Heinrich-Heine-University Düsseldorf (Germany)
  • Universidade Federal de Santa Catarina (Brazil)
  • Universidad de Ciencias y Artes de Chiapas (Mexico)
  • Hamdard University (India)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • STAR Protoc.2024, 5(2):102990.
  • Arch Biochem Biophys.2020, 687:108384.
  • Metabolites.2019, 9(11):E271
  • Cosmetics2021, 8(3),91.
  • J Sci Food Agric.2017, 97(5):1656-1662
  • Antimicrob Agents Chemother.2020, AAC.01921-20.
  • Life Sci.2022, 311(Pt A):121157.
  • ACS Omega.2022, 7(44):40009-40020.
  • J Nat Prod.2018, 81(4):966-975
  • Pharmacol Rep.2017, 69(6):1224-1231
  • Drug Dev Res.2020, doi: 10.1002
  • J Enzyme Inhib Med Chem.2019, 34(1):134-143
  • Horticulture Research2023, uhad164.
  • Sichuan Agricultural University2023, 4630743.
  • J Ethnopharmacol.2019, 236:31-41
  • Food Chem.2019, 274:345-350
  • J Ethnopharmacol.2017, 198:91-97
  • United States Patent Application2020, 20200038363
  • Postharvest Biol Tec2019, 149:18-26
  • Key Engineering Materials2022, 931(47-53).
  • Molecules.2023, 28(4):1785.
  • Food Engineering Progress2019, 23(3)209-216
  • Evid Based Complement Alternat Med.2021, 2021:8707280.
  • ...
  • 生物活性
    Description: Tembetarine has anti-inflammatory and anti-injury properties.Tembetarine was antifeedant against S. frugiperda.
    In vitro:
    Molecules . 2013 Jul 3;18(7):7739-7750.
    Studies on the alkaloids of the bark of Magnolia officinalis: isolation and on-line analysis by HPLC-ESI-MS(n)[Pubmed: 23823874]
    The bark of Magnolia officinalis is a well-known Traditional Chinese Medicine. In the present study, two new alkaloids, named (S)-4-keto-magnoflorine (6) and (R)-3,4-dehydromagnocurarine (11), together with seven known alkaloids: (S)-magnoflorine (5), trans/cis N-feruloylputrescine (7/8), (R)-magnocurarine (10), (S)-tembetarine (12), (R)-oblongine (14), and (R)-asimilobine (17) were isolated and their structures elucidated by spectroscopic methods, including 1D, 2D NMR, and HRESI-MS. The absolute configurations of the isoquinoline alkaloids 5, 6, 10-12, 14, and 17 were determined by CD. In vitro inhibitory activities against aldose reductase, lipase, α-glucosidase, DPP-IV and three cancer cell lines (A549, Bel-7402, and HCT-8) were evaluated for all isolated compounds. However, all compounds showed weak activities in all tests at the same concentration as the positive control drugs. An HPLC-ESI-MS(n) method has been established for screening of alkaloids in the bark of M. officinalis. A total of 23 alkaloids were identified or tentatively characterized; including 13 aporphines, eight benzylisoquinolines and two amides. Plausible fragmentation pathways of the representative compounds 6, 7/8, 11, and 17 were proposed in the present study.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9036 mL 14.518 mL 29.036 mL 58.072 mL 72.59 mL
    5 mM 0.5807 mL 2.9036 mL 5.8072 mL 11.6144 mL 14.518 mL
    10 mM 0.2904 mL 1.4518 mL 2.9036 mL 5.8072 mL 7.259 mL
    50 mM 0.0581 mL 0.2904 mL 0.5807 mL 1.1614 mL 1.4518 mL
    100 mM 0.029 mL 0.1452 mL 0.2904 mL 0.5807 mL 0.7259 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    (R)-牛心果碱; (R)-Reticuline CFN95013 3968-19-2 C19H23NO4 = 329.4 5mg QQ客服:1457312923
    藤泊它碱; Tembetarine CFN95542 18446-73-6 C20H26NO4 = 344.4 5mg QQ客服:1457312923
    衡州乌药碱; 乌药碱; Coclaurine CFN98769 486-39-5 C17H19NO3 = 285.3 5mg QQ客服:2056216494
    新化合物X; New compound 10 CFN95343 N/A C23H29NO8 = 447.5 5mg QQ客服:2159513211
    L-(-)-N-去甲亚美罂粟碱; Norarmepavine CFN96773 3195-01-5 C18H21NO3 = 299.37 5mg QQ客服:1457312923
    杏黄罂粟碱; Armepavine CFN93348 524-20-9 C19H23NO3 = 313.39 10mg QQ客服:1413575084
    N-甲基杏黄罂粟碱; N-Methylarmepavine CFN95612 74046-21-2 C20H26NO3+ = 328.4 5mg QQ客服:1457312923
    N-甲基乌药碱; N-Methylcoclaurine CFN96775 5096-70-8 C18H21NO3 = 299.37 5mg QQ客服:3257982914
    N-甲基去氢乌药碱; N-Methyldehydrococlaurine CFN95588 N/A C18H20NO3+ = 298.4 5mg QQ客服:2159513211
    四氢罂粟碱盐酸盐; Tetrahydropapaverine hydrochloride CFN96626 6429-04-5 C20H26ClNO4 = 379.88 5mg QQ客服:3257982914

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