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  • 赤芝酸A甲酯

    Methyl lucidenate A

    赤芝酸A甲酯
    产品编号 CFN95583
    CAS编号 105742-79-8
    分子式 = 分子量 C28H40O6 = 472.6
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruit body of Ganoderma lucidum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    赤芝酸A甲酯 CFN95583 105742-79-8 1mg QQ客服:2159513211
    赤芝酸A甲酯 CFN95583 105742-79-8 5mg QQ客服:2159513211
    赤芝酸A甲酯 CFN95583 105742-79-8 10mg QQ客服:2159513211
    赤芝酸A甲酯 CFN95583 105742-79-8 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Wisconsin-Madison (USA)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • University of Illinois at Chicago (USA)
  • University of South Australia (Australia)
  • University of Cincinnati (USA)
  • Universiti Malaysia Pahang (Malaysia)
  • Universidade da Beira Interior (Germany)
  • Gyeongsang National University (Korea)
  • Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
  • University of Auckland (New Zealand)
  • Utrecht University (Netherlands)
  • Kitasato University (Japan)
  • Colorado State University (USA)
  • Aarhus University (Denmark)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • The Japan Society for Analytical Chemistry2018, 67(4):201-206
  • Journal of Third Military Medical University2019, 41(2):110-115
  • Phytomedicine.2019, 65:153089
  • Pharmaceuticals.2022, 15(4), 402.
  • J Food Biochem.2020, 44(6):e13198.
  • Planta Med.2019, 85(9-10):766-773
  • Korean J. Medicinal Crop Sci.2022, 30(2):124-133
  • Food Chem.2019, 278:683-691
  • Food Res Int.2021, 148:110607.
  • Foods.2021, 10(12):2929.
  • Nutraceuticals2022, 2(3),150-161
  • Wageningen University & Research2018, January 2018
  • Sains Malaysiana2022, 51(4):1143-1154
  • Oncol Rep.2016, 35(3):1356-64
  • Int Immunopharmacol.2022, 106:108603.
  • Sci Rep.2019, 9(1):6429
  • bioRxiv2021, 462065.
  • Am J Chin Med.2015, 30:1-22
  • Pak J Pharm Sci.2019, 32(6)
  • Int Immunopharmacol.2019, 71:22-31
  • Heliyon.2022, e12337.
  • Histol Histopathol.2022, 18518.
  • Int J Mol Sci.2019, 20(3):E651
  • ...
  • 生物活性
    Description: Methyl lucidenate A had a strong inhibitory effect on EBV-EA induction.
    In vitro:
    J Nat Prod . 2003 Dec;66(12):1582-1585.
    Lucidenic acids P and Q, methyl lucidenate P, and other triterpenoids from the fungus Ganoderma lucidum and their inhibitory effects on Epstein-Barr virus activation[Pubmed: 14695801]
    A new triterpene acid, lucidenic acid P (1a), and two new triterpene acid methyl esters, methyl lucidenates P (1b) and Q (2b), were isolated and characterized from the fruiting body of the fungus Ganoderma lucidum. Their structures were elucidated on the basis of spectroscopic methods. In addition, eight known triterpene acids, lucidenic acids A (3a), C (4a), D(2) (5a), E(2) (6a), and F (7a) and ganoderic acids E (9a), F (10a), and T-Q (11a), and six known triterpene acid methyl esters, methyl lucidenates A (3b), D(2) (5b), E(2) (6b), F (7b), and L (8b) and methyl ganoderate F (10b), were isolated and identified from the fungus. All of the triterpenoids, with the exception of 7a, were evaluated with respect to their inhibitory effects on the induction of Epstein-Barr virus early antigen (EBV-EA) by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells, which is known to be a primary screening test for antitumor promoters. All of the compounds tested showed potent inhibitory effects on EBV-EA induction (96-100% inhibition at 1 x 10(3) mol ratio/TPA).
    Nat Prod Res . 2013;27(1):17-22.
    Triterpenoids from Ganoderma lucidum and their cytotoxic activities[Pubmed: 22263904]
    From the ethyl acetate fraction of the fruiting body of Ganoderma lucidum, a new triterpenoid, ethyl 7β-hydroxy-4,4,14α-trimethyl-3,11,15-trioxo-5α-chol-8-en-24-oate (4), named ethyl lucidenates A, along with three known compounds, ganodermanondiol (1), lucidumol B (2) and methyl lucidenates A (3) were isolated by silica gel column, ODS column chromatography and PHPLC. Their structures were established on the basis of spectroscopic analysis and chemical evidence. The isolated compounds were tested using in vitro MTT assay for their cytotoxic activities against the K562, HL-60, CA46, HepG2, SW480 and SMMC-7221 cancer cell lines. Among them, compound 4 showed cytotoxicity against HL-60 and CA46 cancer cell lines with IC(50) values of 25.98 and 20.42 μg mL(-1), respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.116 mL 10.5798 mL 21.1595 mL 42.3191 mL 52.8989 mL
    5 mM 0.4232 mL 2.116 mL 4.2319 mL 8.4638 mL 10.5798 mL
    10 mM 0.2116 mL 1.058 mL 2.116 mL 4.2319 mL 5.2899 mL
    50 mM 0.0423 mL 0.2116 mL 0.4232 mL 0.8464 mL 1.058 mL
    100 mM 0.0212 mL 0.1058 mL 0.2116 mL 0.4232 mL 0.529 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    灵芝烯酸F; Ganoderenic acid F CFN90301 120462-47-7 C30H38O7 = 510.63 5mg QQ客服:215959384
    灵芝烯酸F甲酯; Methyl ganoderenate F CFN95573 N/A C31H40O7 = 524.7 5mg QQ客服:3257982914
    3β,7β,15β-三羟基-11-羰基-羊毛甾烷-8-烯-24->20内酯; 3beta,7beta,15beta-trihydroxy-11-oxo-lanosta-8-en-24->20 lactone CFN91085 1694587-15-9 C27H40O6 = 460.61 5mg QQ客服:1413575084
    灵芝内酯B; Ganolactone B CFN90748 1028449-53-7 C27H38O6 = 458.6 5mg QQ客服:1457312923
    3β,7β,12β-三羟基-11,15-二羰基-羊毛甾烷-8-烯-24→20内酯; Ganoderlactone D CFN90970 1801934-15-5 C27H38O7 = 474.26 5mg QQ客服:1413575084
    (5alpha)-11-dioxo-7,15-dihydroxy-4,4,14-trimethyl-3-Chol-8-en-24-oic acid; (5alpha)-11-dioxo-7,15-dihydroxy-4,4,14-trimethyl-3-Chol-8-en-24-oic acid CFN91763 942936-54-1 C27H40O6 = 460.61 5mg QQ客服:2159513211
    赤芝酸A; Lucidenic acid A CFN90574 95311-94-7 C27H38O6 = 458.59 20mg QQ客服:1457312923
    赤芝酸A甲酯; Methyl lucidenate A CFN95583 105742-79-8 C28H40O6 = 472.6 5mg QQ客服:3257982914
    赤芝酸E; Lucidenic acid E CFN93125 98665-17-9 C29H40O8 = 516.63 5mg QQ客服:3257982914
    赤芝酸E2甲酯; Methyl lucidenate E2 CFN95569 98665-12-4 C30H42O8 = 530.7 5mg QQ客服:2056216494

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