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  • 赤芝酸A甲酯

    Methyl lucidenate A

    赤芝酸A甲酯
    产品编号 CFN95583
    CAS编号 105742-79-8
    分子式 = 分子量 C28H40O6 = 472.6
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruit body of Ganoderma lucidum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    赤芝酸A甲酯 CFN95583 105742-79-8 1mg QQ客服:3257982914
    赤芝酸A甲酯 CFN95583 105742-79-8 5mg QQ客服:3257982914
    赤芝酸A甲酯 CFN95583 105742-79-8 10mg QQ客服:3257982914
    赤芝酸A甲酯 CFN95583 105742-79-8 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Nat Med.2017, 71(4):745-756
  • Pharmacognosy Journal2019, 11(2): 369-373
  • Chin Med.2022, 17(1):66.
  • Molecules.2020, 25(23):5609.
  • Pharmaceutics.2021, 13(2):187.
  • Biomed Chromatogr.2019, 8:e4774
  • Front Microbiol.2020, 11:583594.
  • University of Central Lancashire2017, 20472
  • Journal of Plant Growth Regulation2022, 10705-2.
  • New Zealand J. Forestry Sci.2014, 44:17
  • J Ethnopharmacol.2017, 209:305-316
  • Appl. Sci. 2021, 11(1),14.
  • Int. J. Mol. Sci.2022, 23(14),7699;
  • J Mol Recognit.2020, 33(2):e2819
  • RSC Advances2017, 86
  • Research Square2021, 10.21203.
  • Cells.2021, 10(11):2919.
  • Korean Journal of Pharmacognosy2018, 49(3):270-277
  • JEJU National University2022, 24032.
  • Heliyon.2022, e12337.
  • Asian J Beauty Cosmetol2021, 19(1): 57-64.
  • Int J Mol Sci.2022, 23(11):6172.
  • J of Ana. Chem.2019, 74(11):1113-1121
  • ...
  • 生物活性
    Description: Methyl lucidenate A had a strong inhibitory effect on EBV-EA induction.
    In vitro:
    J Nat Prod . 2003 Dec;66(12):1582-1585.
    Lucidenic acids P and Q, methyl lucidenate P, and other triterpenoids from the fungus Ganoderma lucidum and their inhibitory effects on Epstein-Barr virus activation[Pubmed: 14695801]
    A new triterpene acid, lucidenic acid P (1a), and two new triterpene acid methyl esters, methyl lucidenates P (1b) and Q (2b), were isolated and characterized from the fruiting body of the fungus Ganoderma lucidum. Their structures were elucidated on the basis of spectroscopic methods. In addition, eight known triterpene acids, lucidenic acids A (3a), C (4a), D(2) (5a), E(2) (6a), and F (7a) and ganoderic acids E (9a), F (10a), and T-Q (11a), and six known triterpene acid methyl esters, methyl lucidenates A (3b), D(2) (5b), E(2) (6b), F (7b), and L (8b) and methyl ganoderate F (10b), were isolated and identified from the fungus. All of the triterpenoids, with the exception of 7a, were evaluated with respect to their inhibitory effects on the induction of Epstein-Barr virus early antigen (EBV-EA) by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells, which is known to be a primary screening test for antitumor promoters. All of the compounds tested showed potent inhibitory effects on EBV-EA induction (96-100% inhibition at 1 x 10(3) mol ratio/TPA).
    Nat Prod Res . 2013;27(1):17-22.
    Triterpenoids from Ganoderma lucidum and their cytotoxic activities[Pubmed: 22263904]
    From the ethyl acetate fraction of the fruiting body of Ganoderma lucidum, a new triterpenoid, ethyl 7β-hydroxy-4,4,14α-trimethyl-3,11,15-trioxo-5α-chol-8-en-24-oate (4), named ethyl lucidenates A, along with three known compounds, ganodermanondiol (1), lucidumol B (2) and methyl lucidenates A (3) were isolated by silica gel column, ODS column chromatography and PHPLC. Their structures were established on the basis of spectroscopic analysis and chemical evidence. The isolated compounds were tested using in vitro MTT assay for their cytotoxic activities against the K562, HL-60, CA46, HepG2, SW480 and SMMC-7221 cancer cell lines. Among them, compound 4 showed cytotoxicity against HL-60 and CA46 cancer cell lines with IC(50) values of 25.98 and 20.42 μg mL(-1), respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.116 mL 10.5798 mL 21.1595 mL 42.3191 mL 52.8989 mL
    5 mM 0.4232 mL 2.116 mL 4.2319 mL 8.4638 mL 10.5798 mL
    10 mM 0.2116 mL 1.058 mL 2.116 mL 4.2319 mL 5.2899 mL
    50 mM 0.0423 mL 0.2116 mL 0.4232 mL 0.8464 mL 1.058 mL
    100 mM 0.0212 mL 0.1058 mL 0.2116 mL 0.4232 mL 0.529 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    灵芝烯酸D; Ganoderenic acid D CFN90300 100665-43-8 C30H40O7 = 512.64 20mg QQ客服:2056216494
    灵芝烯酸D甲酯; Methyl ganoderenate D CFN95572 748136-03-0 C31H42O7 = 526.7 5mg QQ客服:1413575084
    紫芝烯酸C; Ganosinensic acid C CFN95567 2231756-23-1 C30H40O7 = 512.6 5mg QQ客服:1457312923
    灵芝烯酸E; Ganoderenic acid E CFN91024 110241-23-1 C30H40O8 = 528.63 5mg QQ客服:2159513211
    灵芝酸L; Ganoderic acid L CFN95022 102607-24-9 C30H46O8 = 534.7 5mg QQ客服:3257982914
    灵芝酸I; Ganoderic acid I CFN90740 98665-20-4 C30H44O8 = 532.67 5mg QQ客服:1413575084
    灵芝烯酸C; Ganoderenic acid C CFN92238 100665-42-7 C30H44O7 = 516.7 5mg QQ客服:2056216494
    灵芝烯酸H; Ganoderenic acid H CFN90302 120462-48-8 C30H40O7 = 512.64 5mg QQ客服:1413575084
    灵芝烯酸F; Ganoderenic acid F CFN90301 120462-47-7 C30H38O7 = 510.63 5mg QQ客服:3257982914
    灵芝烯酸F甲酯; Methyl ganoderenate F CFN95573 N/A C31H40O7 = 524.7 5mg QQ客服:215959384

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