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  • 赤芝酸C

    Lucidenic acid C

    赤芝酸C
    产品编号 CFN92995
    CAS编号 95311-96-9
    分子式 = 分子量 C27H40O7 = 476.60
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruit body of Ganoderma lucidum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    赤芝酸C CFN92995 95311-96-9 1mg QQ客服:1413575084
    赤芝酸C CFN92995 95311-96-9 5mg QQ客服:1413575084
    赤芝酸C CFN92995 95311-96-9 10mg QQ客服:1413575084
    赤芝酸C CFN92995 95311-96-9 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Chang Gung University (Taiwan)
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  • Semmelweis Unicersity (Hungary)
  • Kyoto University (Japan)
  • Melbourne University (Australia)
  • Seoul National University of Science and Technology (Korea)
  • Medizinische Universit?t Wien (Austria)
  • Wageningen University (Netherlands)
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  • Agricultural Research Organization (ARO) (Israel)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Comput Biol Chem.2019, 83:107096
  • Int J Mol Sci.2021, 22(10):5181.
  • Korean J. Medicinal Crop Sci.2022, 30(2):117-123.
  • Biomol Ther (Seoul).2023, 31(1):40-47.
  • Int. J. Mol. Sci.2022, 23(14),7699;
  • Pharmaceutics.2020, 12(9):845.
  • Nutrients.2020, 12(5):1242.
  • Food Chem.2019, 279:80-87
  • Appl. Sci.2020, 10(20), 7323.
  • Cancers (Basel).2021, 13(9):2223.
  • Phytomedicine.2016, 23(4):331-9
  • Molecules.2017, 22(2)
  • Plos One.2019, 15(2):e0220084
  • US20170000760 A12016, 42740
  • GENENCELL2023, 25:4356740
  • Appl. Sci.2020, 10(5),1713.
  • Processes2022, 10(10), 2008.
  • J Ethnopharmacol.2017, 198:87-90
  • Int J Mol Sci.2022, 23(21):13406.
  • Nutrients.2021, 13(8):2901.
  • Plant Physiol Biochem.2021, 160:166-174.
  • BioResources J.2020, 15(3).
  • Biosci Rep.2018, 38(4)
  • ...
  • 生物活性
    Description: Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.
    Targets: MMP(e.g.TIMP)
    In vitro:
    Mol Nutr Food Res. 2007 Dec;51(12):1472-7.
    The anti-invasive effect of lucidenic acids isolated from a new Ganoderma lucidum strain.[Pubmed: 17979098 ]
    Ganoderma lucidum is a well-known mushroom with various pharmacological effects that has been used for health and longevity purposes. The objective of this study was to investigate the anti-invasive effect of lucidenic acids isolated from a new G. lucidum strain (YK-02) against human hepatoma carcinoma (HepG(2)) cells.
    METHODS AND RESULTS:
    Triterpenoid components in the ethanol extract of G. lucidum (YK-02) were separated by means of a semi-preparative RP HPLC. Four major peaks were separated and crystallized from triterpenoids fraction, and were identified as lucidenic acid A, lucidenic acid B, Lucidenic acid C, and lucidenic acid N according to their spectroscopic values of (1)H NMR and MS. Treatment of the lucidenic acids (50 microM) in the presence of 200 nM phorbol 12-myristate 13-acetate (PMA) after 24 h of incubation all resulted in significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.
    CONCLUSIONS:
    The results indicate that the lucidenic acids isolated from G. lucidum (YK-02) are anti-invasive bioactive components on hepatoma cells.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0982 mL 10.491 mL 20.982 mL 41.9639 mL 52.4549 mL
    5 mM 0.4196 mL 2.0982 mL 4.1964 mL 8.3928 mL 10.491 mL
    10 mM 0.2098 mL 1.0491 mL 2.0982 mL 4.1964 mL 5.2455 mL
    50 mM 0.042 mL 0.2098 mL 0.4196 mL 0.8393 mL 1.0491 mL
    100 mM 0.021 mL 0.1049 mL 0.2098 mL 0.4196 mL 0.5245 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    赤芝酸D2; Lucidenic acid D2 CFN95020 98665-16-8 C29H38O8 = 514.6 5mg QQ客服:1413575084
    赤芝酸C; Lucidenic acid C CFN92995 95311-96-9 C27H40O7 = 476.60 5mg QQ客服:215959384
    赤芝酸C甲酯; Methyl lucidenate C CFN95541 N/A C28H42O7 = 490.6 5mg QQ客服:2056216494
    赤芝酸SP1; Lucidenic acid SP1 (Lucidenic acid LM1) CFN92994 364622-33-3 C27H40O6 = 460.60 5mg QQ客服:2159513211
    20(21)-脱氢赤芝酸A; 20(21)-Dehydrolucidenic acid A CFN90829 852936-69-7 C27H36O6 = 456.6 10mg QQ客服:3257982914
    赤芝酮B; Lucidone B CFN91025 97653-93-5 C24H32O5 = 400.51 5mg QQ客服:2159513211
    灵芝酸G; Ganoderic acid G CFN90801 98665-22-6 C30H44O8 = 532.7 20mg QQ客服:2159513211
    20-羟基灵芝酸G; 20-Hydroxyganoderic acid G CFN91014 400604-12-8 C30H44O9 = 548.67 5mg QQ客服:2159513211
    灵芝酸N; Ganoderic acid N CFN90293 110241-19-5 C30H42O8 = 530.65 10mg QQ客服:215959384
    灵芝烯酸A; Ganoderenic acid A CFN92236 100665-40-5 C30H42O7 = 514.7 10mg QQ客服:3257982914

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