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  • 赤芝酸SP1

    Lucidenic acid SP1 (Lucidenic acid LM1)

    赤芝酸SP1
    产品编号 CFN92994
    CAS编号 364622-33-3
    分子式 = 分子量 C27H40O6 = 460.60
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruit body of Ganoderma lucidum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    赤芝酸SP1 CFN92994 364622-33-3 1mg QQ客服:1413575084
    赤芝酸SP1 CFN92994 364622-33-3 5mg QQ客服:1413575084
    赤芝酸SP1 CFN92994 364622-33-3 10mg QQ客服:1413575084
    赤芝酸SP1 CFN92994 364622-33-3 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Hawaii Cancer Center (USA)
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  • Max Rubner-Institut (MRI) (Germany)
  • The Australian National University (Australia)
  • Kazusa DNA Research Institute (Japan)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Front Pharmacol.2021, 12:615157.
  • Int J Mol Sci.2021, 22(11):5503.
  • Molecules.2018, 23(3):E615
  • Applied Biological Chemistry2023, 66(58):112.
  • J Mol Histol.2019, 50(4):343-354
  • Internoational J of Toxicology2020, 10.1177.
  • Tropical J. of Pha. Research2017, 16(3):543-552
  • Microchemical Journal2024: 196:109676.
  • J Applied Biological Chemistry2021, 64(2):185-192
  • Evid Based Complement Alternat Med.2017, 2017:7383104
  • Molecules.2018, 23(12):E3103
  • Aging (Albany NY).2021, 13(19):22867-22882.
  • Plants (Basel).2023, 12(1):163.
  • Pharmacognosy Journal2019, 11,6:1235-1241
  • Biosci Biotechnol Biochem.2020, 84(3):621-632
  • J Nat Prod.2019, 82(4):1002-1008
  • Life (Basel).2022, 12(12):2107.
  • Int J Cosmet Sci.2023, 45(2):155-165.
  • Pharmaceutical Chemistry Journal2019, 52(12):986-991
  • Separations2021, 8(6),80.
  • Oncol Rep.2019, 41(4):2453-2463
  • Free Radic Biol Med.2016, 97:307-319
  • Phytomedicine.2017, 24:77-86
  • ...
  • 生物活性
    Description: Reference standards.
    In vitro:
    Planta Med. 2001 Dec;67(9):811-4.
    Anticomplement activity of terpenoids from the spores of Ganoderma lucidum.[Pubmed: 11745016]
    A new lanostane-type terpenoid, Lucidenic acid SP1 (1), was isolated from a CHCl(3)-soluble fraction of Ganoderma lucidum spores together with four other known compounds (2 - 5).
    METHODS AND RESULTS:
    The structure of Lucidenic acid SP1 was determined to be 3 beta,7 beta-dihydroxy-4,4,14 alpha-trimethyl-11,15-dioxo-5 alpha-chol-8-en-24-oic acid by spectroscopic means including 2D-NMR. Twelve triterpenes (1-12) isolated from G. lucidum spores were investigated in vitro for their anticomplementary activity.
    CONCLUSIONS:
    Compounds 1 - 5 were inactive, whereas ganoderiol F (8), ganodermanondiol (9) and ganodermanontriol (10) showed a strong anticomplement activity against the classical pathway (CP) of the complement system with IC(50) values of 4.8, 41.7, and 17.2 microM, respectively. The potency of these triterpene alcohols (8-10) in inhibiting CP activity was improved when the number of hydroxymethyl groups on the side chain moiety is increased. On the other hand, the ganoderic acids 1-7, which contain a carboxyl group in the side chain, and lucidumols A and B (11, 12) had little activity on this system.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1711 mL 10.8554 mL 21.7108 mL 43.4216 mL 54.277 mL
    5 mM 0.4342 mL 2.1711 mL 4.3422 mL 8.6843 mL 10.8554 mL
    10 mM 0.2171 mL 1.0855 mL 2.1711 mL 4.3422 mL 5.4277 mL
    50 mM 0.0434 mL 0.2171 mL 0.4342 mL 0.8684 mL 1.0855 mL
    100 mM 0.0217 mL 0.1086 mL 0.2171 mL 0.4342 mL 0.5428 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    灵芝烯酸H; Ganoderenic acid H CFN90302 120462-48-8 C30H40O7 = 512.64 5mg QQ客服:215959384
    灵芝烯酸F; Ganoderenic acid F CFN90301 120462-47-7 C30H38O7 = 510.63 5mg QQ客服:1413575084
    灵芝烯酸F甲酯; Methyl ganoderenate F CFN95573 N/A C31H40O7 = 524.7 5mg QQ客服:2159513211
    3β,7β,15β-三羟基-11-羰基-羊毛甾烷-8-烯-24->20内酯; 3beta,7beta,15beta-trihydroxy-11-oxo-lanosta-8-en-24->20 lactone CFN91085 1694587-15-9 C27H40O6 = 460.61 5mg QQ客服:215959384
    灵芝内酯B; Ganolactone B CFN90748 1028449-53-7 C27H38O6 = 458.6 5mg QQ客服:3257982914
    3β,7β,12β-三羟基-11,15-二羰基-羊毛甾烷-8-烯-24→20内酯; Ganoderlactone D CFN90970 1801934-15-5 C27H38O7 = 474.26 5mg QQ客服:215959384
    (5alpha)-11-dioxo-7,15-dihydroxy-4,4,14-trimethyl-3-Chol-8-en-24-oic acid; (5alpha)-11-dioxo-7,15-dihydroxy-4,4,14-trimethyl-3-Chol-8-en-24-oic acid CFN91763 942936-54-1 C27H40O6 = 460.61 5mg QQ客服:2159513211
    赤芝酸A; Lucidenic acid A CFN90574 95311-94-7 C27H38O6 = 458.59 20mg QQ客服:2056216494
    赤芝酸A甲酯; Methyl lucidenate A CFN95583 105742-79-8 C28H40O6 = 472.6 5mg QQ客服:215959384
    赤芝酸E; Lucidenic acid E CFN93125 98665-17-9 C29H40O8 = 516.63 5mg QQ客服:2056216494

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