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  • 3'-O-甲基紫黄檀素

    3'-O-Methylviolanone

    3'-O-甲基紫黄檀素
    产品编号 CFN95387
    CAS编号 56973-42-3
    分子式 = 分子量 C18H18O6 = 330.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The roots of Parochetus communis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    3'-O-甲基紫黄檀素 CFN95387 56973-42-3 1mg QQ客服:1413575084
    3'-O-甲基紫黄檀素 CFN95387 56973-42-3 5mg QQ客服:1413575084
    3'-O-甲基紫黄檀素 CFN95387 56973-42-3 10mg QQ客服:1413575084
    3'-O-甲基紫黄檀素 CFN95387 56973-42-3 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of the Basque Country (Spain)
  • Research Unit Molecular Epigenetics (MEG) (Germany)
  • University of Stirling (United Kingdom)
  • Lund University (Sweden)
  • University of Bordeaux (France)
  • Lodz University of Technology (Poland)
  • University of Wollongong (Australia)
  • Celltrion Chemical Research Institute (Korea)
  • University of Auckland (New Zealand)
  • University of Fribourg (Switzerland)
  • University of Toronto (Canada)
  • Monash University (Australia)
  • Universidade Católica Portuguesa (Portugal)
  • Heinrich-Heine-University Düsseldorf (Germany)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Pharmacogn Mag.2015, 11(43):562-6
  • Natural Product Communications2020, doi: 10.1177.
  • Biomed Pharmacother.2022, 145:112474.
  • J Agric Food Chem.2021, 69(46):14037-14047.
  • Journal of Third Military Medical University2018, 40(12):1073-1078
  • Oxid Med Cell Longev.2020, 2020:8887251.
  • Life Sci.2021, 270:119074.
  • Biomed Pharmacother.2021, 137:111362.
  • Pak J Pharm Sci.2019, 32(6):2879-2885
  • J Agric Food Chem.2015, 63(44):9869-78
  • Nutrients.2018, 10(7)
  • Mol Neurobiol.2021, 58(8):3665-3676.
  • Sci Rep. 2018, 10590
  • Antioxidants.2022, 11(4), 67.
  • Journal of Analytical Chemistry2017, 854-861
  • ACS Synth Biol.2022, doi: 10.1021.
  • Rev. Chim.2020, 71(3),558-564
  • Life Sci.2021, 286:120019.
  • Plant Biotechnology Reports 2021, 15:117-124.
  • Nat Commun.2019, 10(1):2745
  • New Zealand J. Forestry Sci.2014, 44:17
  • Anesth Pain Med (Seoul).2020, 15(4):478-485.
  • J Nat Prod.2022, doi: 10.1021
  • ...
  • 生物活性
    Description: 3'-O-methylviolanone has anti-inflammatory activity .
    In vitro:
    Planta Med . 1998 Mar;64(2):153-8. doi: 10.1055/s-2006-957394.
    Three new flavonoids and antiallergic, anti-inflammatory constituents from the heartwood of Dalbergia odorifera[Pubmed: 9525107]
    Three new flavonoids, (3R)-4'-methoxy-2',3,7-trihydroxyisoflavanone (11), 7-methoxy-3,3',4',6-tetrahydroxyflavone (18), and 2',7-dihydroxy-4',5'-dimethoxyisoflavone (22), were isolated from the heartwood of Dalbergia odorifera T. Chen. (Leguminosae), together with twenty-two known compounds, (S)-4-methoxydalbergione (1), cearoin (2), medicarpin (3), formononetin (4), sativanone (5), 3-hydroxy-9-methoxy-coumestan (6), meliotocarpan A (7), isoliquiritigenin (8), stevein (9), liquiritigenin (10), 3',4',7-trihydroxyflavanone (12), butein (13), 3'-hydroxymelanettin (14), koparin (15), bowdichione (16), fisetin (17), melanettin (19), sulfuretin (20), 3'-hydroxydaidzein (21), 3'-O-methylviolanone (23), xenognosin B (24), and dalbergin (25). These flavonoids were evaluated in antiallergic and anti-inflammatory tests. The results showed that (S)-4-methoxydalbergione (1) and cearoin (2) exhibited antiallergic activity while (S)-4-methoxydalbergione (1), cearoin (2), butein (13), koparin (15), bowdichione (16), 3'-O-methylviolanone (23), and xenognosin B (24) showed significant anti-inflammatory activity.
    Molecules . 2021 Sep 4;26(17):5381.
    Dihydroisocoumarins and Dihydroisoflavones from the Rhizomes of Dioscorea collettii with Cytotoxic Activity and Structural Revision of 2,2'-Oxybis(1,4-di-tert-butylbenzene)[Pubmed: 34500814]
    The investigation of the constituents of the rhizomes of Dioscorea collettii afforded one new dihydroisocoumarin, named (-)-montroumarin (1a), along with five known compounds-montroumarin (1b), 1,1'-oxybis(2,4-di-tert-butylbenzene) (2), (3R)-3'-O-methylviolanone (3a), (3S)-3'-O-methylviolanone (3b), and (RS)-sativanone (4). Their structures were elucidated using extensive spectroscopic methods. To the best of our knowledge, compound 1a is a new enantiomer of compound 1b. The NMR data of compound 2 had been reported but its structure was erroneous. The structure of compound 2 was revised on the basis of a reinterpretation of its NMR data (1D and 2D) and the assignment of the 1H and 13C NMR data was given rightly for the first time. Compounds 3a-4, three dihydroisoflavones, were reported from the Dioscoreaceae family for the first time. The cytotoxic activities of all the compounds were tested against the NCI-H460 cell line. Two dihydroisocoumarins, compounds 1a and 1b, displayed moderate cytotoxic activities, while the other compounds showed no cytotoxicity.
    Antioxidants (Basel) . 2020 Apr 10;9(4):306.
    Polyphenols and Sesquiterpene Lactones from Artichoke Heads: Modulation of Starch Digestion, Gut Bioaccessibility, and Bioavailability following In Vitro Digestion and Large Intestine Fermentation[Pubmed: 32290151]
    Artichoke is a relevant source of health-promoting compounds such as polyphenols and sesquiterpene lactones. In this study, the bioaccessibility and gut bioavailability of artichoke constituents were evaluated by combining in vitro digestion and large intestine fermentation, metabolomics, and Caco-2 human intestinal cells model. Moreover, the ability of artichoke polyphenols to modulate the in vitro starch digestibility was also explored. An untargeted metabolomic approach based on liquid chromatography quadrupole-time-of-flight (UHPLC/QTOF) mass spectrometry coupled with multivariate statistics was used to comprehensively screen the phytochemical composition of raw, digested, and fermented artichoke. Overall, a large abundance of phenolic acids and sesquiterpene lactones was detected, being 13.77 and 11.99 mg·g-1, respectively. After 20 h of in vitro large intestine fermentation, a decrease in polyphenols and sesquiterpene lactones content was observed. The most abundant compounds characterizing the raw material (i.e., chlorogenic acid and cynaropicrin equivalents) showed an average % bioaccessibility of 1.6%. The highest % bioaccessibility values were recorded for flavonoids such as anthocyanin and flavone equivalents (on average, 13.6%). However, the relatively high bioavailability values recorded for flavonols, phenolic acids, and sesquiterpene lactones (from 71.6% up to 82.4%) demonstrated that these compounds are able to be transported through the Caco-2 monolayer. The phenolic compounds having the highest permeation rates through the Caco-2 model included low molecular weight phenolics such as tyrosol and 4-ethylcatechol; the isoflavonoids 3'-O-methylviolanone, equol 4'-O-glucuronide, and hydroxyisoflavone; together with the methyl and acetyl derivatives of glycosylated anthocyanins. Therefore, although human in vivo confirmatory trials are deemed possible, current findings provide insights into the mechanistic effects underlying artichoke polyphenols and sesquiterpenoids bioavailability following gastrointestinal and large intestine processes.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.0276 mL 15.1378 mL 30.2755 mL 60.551 mL 75.6888 mL
    5 mM 0.6055 mL 3.0276 mL 6.0551 mL 12.1102 mL 15.1378 mL
    10 mM 0.3028 mL 1.5138 mL 3.0276 mL 6.0551 mL 7.5689 mL
    50 mM 0.0606 mL 0.3028 mL 0.6055 mL 1.211 mL 1.5138 mL
    100 mM 0.0303 mL 0.1514 mL 0.3028 mL 0.6055 mL 0.7569 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    4’7-二甲氧基-5-羟基异黄酮; 7-O-Methylbiochanin A CFN91010 34086-51-6 C17H14O5 = 298.3 10mg QQ客服:3257982914
    樱黄素; Prunetin CFN90189 552-59-0 C16H12O5 = 284.26 20mg QQ客服:2932563308
    6-Methylgenistein; 6-Methylgenistein CFN96540 97575-49-0 C16H12O5 = 284.26 5mg QQ客服:1148253675
    6,7,4'-三羟基异黄酮; 6,7,4'-Trihydroxyisoflavone CFN90796 17817-31-1 C15H10O5 = 270.2 5mg QQ客服:2932563308
    黄豆黄素; Glycitein CFN99106 40957-83-3 C16H12O5 = 284.26 20mg QQ客服:2932563308
    Afrormosine; Afrormosine CFN92347 550-79-8 C17H14O5 = 298.3 5mg QQ客服:1413575084
    鸢尾黄素; Tectorigenin CFN99920 548-77-6 C16H12O6 = 300.26 20mg QQ客服:1148253675
    鸢尾甲黄素A; Iristectorigenin A CFN91672 39012-01-6 C17H14O7 = 330.29 10mg QQ客服:2159513211
    甘草宁N; Gancaonin N CFN95066 129145-52-4 C21H20O6 = 368.4 5mg QQ客服:3257982914
    甘草宁 G; Gancaonin G CFN96524 126716-34-5 C21H20O5 = 352.39 5mg QQ客服:3257982914

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