紫黄檀素

Violanone

	产品编号	CFN95385
	CAS编号	52250-38-1
	分子式 = 分子量	C₁₇H₁₆O₆ = 316.3
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Flavonoids
	植物来源	The roots of Parochetus communis
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
紫黄檀素	CFN95385	52250-38-1	1mg	QQ客服：2159513211
紫黄檀素	CFN95385	52250-38-1	5mg	QQ客服：2159513211
紫黄檀素	CFN95385	52250-38-1	10mg	QQ客服：2159513211
紫黄檀素	CFN95385	52250-38-1	20mg	QQ客服：2159513211

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

University of Pretoria (South Africa)

John Innes Centre (United Kingdom)

Korea Food Research Institute(KFRI) (Korea)

Heidelberg University (Germany)

Chungnam National University (Korea)

University of Medicine and Pharmacy (Romania)

Martin Luther University of Halle-Wittenberg (Germany)

China Medical University (Taiwan)

Center for protein Engineering (CIP) (Belgium)

The Ohio State University (USA)

Centralised Purchases Unit (CPU), B.I.T.S (India)

Institute of Pathophysiology Medical University of Vienna (Austria)

Instituto de Investigaciones Agropecuarias (Chile)

University of Hertfordshire (United Kingdom)

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Description:

Violanone, an isoflavanone compound, can inhibit tubulin polymerization. Violanone also exhibits larvicidal activity against A. aegypti.

In vitro:

Exp Parasitol . 2015 Jun;153:160-164.

Extract of Bowdichia virgilioides and maackiain as larvicidal agent against Aedes aegypti mosquito[Pubmed: 25819294]

The larvicidal activities of extracts of three hardwood species (Hymenaea stigonorcapa, Anadenanthera colubrina and Bowdichia virgilioides) against 4th instar larvae of Aedes aegypti were evaluated using WHO guidelines. Extracts of H. stignocarpa and A. colubrina showed weak activity. The highest larvicidal effect was obtained with the cyclohexane extract of the heartwood of B. virgilioides, which caused 100% mortality at concentrations at 50 and 100 μg/mL. Fraction toluene/EtOAc (8:2) from this extract showed larvicidal activity (LC₅₀ = 34.90 ± 1.27 μg/mL). A mixture of two compounds identified as medicarpin and maackiain exhibited a very good larvicidal activity (sub-fraction 2, LC₅₀ = 17.5 ± 1.87 μg/mL) and maackiain showed to be a strong larvicidal compound (LC₅₀ = 21.95 ± 1.34 μg/mL). This result can be of value in the search for new natural larvicidal compounds from other hardwood plant extracts and presents the first report of B. virgilioides being used to control a mosquito vector.

Tetrahedron. 2007 Dec 24; 63(52): 12986-12993.

Synthesis and biological evaluation of isoflavone analogues from Dalbergia oliveri[Reference: WebLink]

Mucronulatol 1 and violanone 2 isolated from Dalbergia oliveri Gamble, and the corresponding isoflavone 3 were prepared by ligand coupling reactions involving organolead reagent. Biological studies have shown a significant cytotoxic effect against an HBL100 leukemia cell line only for isoflavan 1 with an IC50 value amounting to 5.7 μM. All the drugs modestly inhibit the in vitro microtubule assembly, independently of the cytotoxic ability. Natural compounds 1 and 2 have no antibacterial activity, but are potent inhibitors of the Fusarium oxysporum phytopathogenic fungal growth.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
Irilone; Irilone	CFN93694	41653-81-0	C₁₆H₁₀O₆ = 298.25	5mg	QQ客服：1413575084
鸢尾甲黄素A; Iristectorigenin A	CFN91672	39012-01-6	C₁₇H₁₄O₇ = 330.29	20mg	QQ客服：1413575084
甘草宁N; Gancaonin N	CFN95066	129145-52-4	C₂₁H₂₀O₆ = 368.4	5mg	QQ客服：215959384
甘草宁 G; Gancaonin G	CFN96524	126716-34-5	C₂₁H₂₀O₅ = 352.39	5mg	QQ客服：1457312923
刺桐素 G; Erythrinin G	CFN96545	1616592-61-0	C₂₀H₁₈O₆ = 354.35	5mg	QQ客服：2056216494
刺桐素 F; Erythrinin F	CFN96549	1616592-60-9	C₂₀H₁₈O₇ = 370.35	5mg	QQ客服：1457312923
刺桐素 D; Erythrinin D	CFN96546	1616592-59-6	C₂₁H₁₈O₆ = 366.37	5mg	QQ客服：215959384
异补骨脂香豆素A; Isoficusin A	CFN96554	1914963-20-4	C₂₅H₂₄O₅ = 404.47	5mg	QQ客服：2056216494
5-甲基-7-甲氧基异黄酮; 5-Methyl-7-methoxyisoflavone	CFN93022	82517-12-2	C₁₇H₁₄O₃ = 266.29	5mg	QQ客服：1457312923
Sativanone; Sativanone	CFN95388	70561-31-8	C₁₇H₁₆O₅ = 300.3	10mg	QQ客服：215959384

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.1616 mL	15.8078 mL	31.6156 mL	63.2311 mL	79.0389 mL
5 mM	0.6323 mL	3.1616 mL	6.3231 mL	12.6462 mL	15.8078 mL
10 mM	0.3162 mL	1.5808 mL	3.1616 mL	6.3231 mL	7.9039 mL
50 mM	0.0632 mL	0.3162 mL	0.6323 mL	1.2646 mL	1.5808 mL
100 mM	0.0316 mL	0.1581 mL	0.3162 mL	0.6323 mL	0.7904 mL