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  • Mayteine

    Mayteine

    Mayteine
    产品编号 CFN92119
    CAS编号 104736-05-2
    分子式 = 分子量 C43H49NO18 = 867.9
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Sesquiterpenoids
    植物来源 The roots barks from Maytenus robusta Reiss.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Mayteine CFN92119 104736-05-2 1mg QQ客服:1457312923
    Mayteine CFN92119 104736-05-2 5mg QQ客服:1457312923
    Mayteine CFN92119 104736-05-2 10mg QQ客服:1457312923
    Mayteine CFN92119 104736-05-2 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Wuerzburg (Germany)
  • Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)
  • University of Wollongong (Australia)
  • Sanford Burnham Medical Research Institute (USA)
  • Kitasato University (Japan)
  • Worcester Polytechnic Institute (USA)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Macau University of Science and Technology (China)
  • Siksha O Anusandhan University (India)
  • Yale University (USA)
  • Julius Kühn-Institut (Germany)
  • Utrecht University (Netherlands)
  • Cancer Research Initatives Foundation(CARIF) (Malaysia)
  • National Chung Hsing University (Taiwan)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Phytomedicine.2019, 57:95-104
  • Korean J. Food Sci. & Technol.2022, 54(2):241-246
  • Appl. Sci.2021, 11(24),12080
  • Oxid Med Cell Longev.2021, 2021:4883398.
  • Food and Fermentation Industries2018, 44(371)
  • J Biochem Mol Toxicol.2020, 34(7):e22489.
  • Int J Mol Sci.2019, 20(23):E6071
  • Phytother Res.2020, 34(4):788-795.
  • Anat Rec (Hoboken).2021, 304(2):323-332.
  • Int J Immunopathol Pharmacol.2019, 33:2058738419857537
  • JAOCS2021, 98(7):779-794.
  • Molecules.2019, 24(6):E1177
  • Int J Mol Sci.2022, 23(21):12816.
  • Research on Crops.2017, 18(2)
  • LWT2021, 138:110630.
  • Biosci. Rep.2020, 10.1024
  • British Jou. Med.&Med. Research2014, 1802-1811
  • J Formos Med Assoc.2020, S0929-6646(20)30425-3
  • Cell.2018, 172(1-2):249-261
  • Int J Mol Sci.2019, 20(9):E2244
  • Talanta.2022, 249:123645.
  • Food Res Int.2022, 157:111207.
  • Arch Biochem Biophys.2018, 644:93-99
  • ...
  • 生物活性
    Description: Mayteine may have gastroprotective activity.
    In vitro:
    J Nat Prod. 2004 Jan;67(1):14-8.
    Insecticidal sesquiterpene pyridine alkaloids from Maytenus chiapensis.[Pubmed: 14738378 ]

    METHODS AND RESULTS:
    The new sesquiterpene pyridine alkaloids chiapenines ES-I (1), ES-II (2), ES-III (3), and ES-IV (4), in addition to the known alkaloids wilfordine (5), alatamine (6), wilforidine (7), alatusinine (8), euonine (9), euonymine (10), ebenifoline E-I (11), forrestine (12), Mayteine (13), and 4-hydroxy-7-epi-chuchuhuanine E-V (14), were isolated from the leaves of Maytenus chiapensis.
    CONCLUSIONS:
    Their structures were elucidated by 1D and 2D NMR spectroscopy, including homonuclear and heteronuclear correlation (COSY, ROESY, HSQC, and HMBC) experiments. Wilfordine, alatusinine, and euonine exhibited strong antifeedant activity against Spodoptera littoralis.
    In vivo:
    Nat Prod Commun. 2016 May;11(5):597-9.
    Phytochemical Analysis and Gastroprotective Activity of the Root Bark from Maytenus robusta.[Pubmed: 27319126]
    The present work evaluated the chemical composition and antiulcerogenic potential of the crude extract, fractions and pure compounds isolated of roots barks from Maytenus robusta Reiss, using different pharmacological models in mice.
    METHODS AND RESULTS:
    3,12-Dioxofriedelane (1) and 11-hydroxylup-20 (29)-en-3-one (2) were isolated from the n-hexane fraction, and mayteine (3) and 3,7-dioxofriedelane (4) from the dichloromethane fraction. The crude extract (50, 259, 500 mg/kg), all the fractions (250 mg/kg) and cimetidine (100 mg/kg) significantly reduced the lesion index, total lesion area, and percentage of lesions, in comparison with the control group (p < 0.05), by ethanol and NSAID-induced ulcer models. All the isolated compounds also presented significant pharmacological effects at 30 mg/kg.
    CONCLUSIONS:
    These results show that the root bark of M. robusta may be a promising source of molecules with applicability in the treatment of gastric disorders.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.1522 mL 5.761 mL 11.5221 mL 23.0441 mL 28.8052 mL
    5 mM 0.2304 mL 1.1522 mL 2.3044 mL 4.6088 mL 5.761 mL
    10 mM 0.1152 mL 0.5761 mL 1.1522 mL 2.3044 mL 2.8805 mL
    50 mM 0.023 mL 0.1152 mL 0.2304 mL 0.4609 mL 0.5761 mL
    100 mM 0.0115 mL 0.0576 mL 0.1152 mL 0.2304 mL 0.2881 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    雷公藤宁碱A; Wilfornine A CFN92120 345954-00-9 C45H51NO20 = 925.9 5mg QQ客服:2159513211
    雷公藤次碱; Wilforine CFN99207 11088-09-8 C43H49NO18 = 867.9 20mg QQ客服:1413575084
    鬼箭羽碱,叶含卫矛碱; Alatamine CFN92121 41855-33-8 C41H45NO18 = 839.8 5mg QQ客服:2056216494
    雷公藤定碱; Wilfordine CFN92103 37239-51-3 C43H49NO19 = 883.9 5mg QQ客服:1413575084
    Peritassine A; Peritassine A CFN92104 150881-01-9 C38H47NO18 = 805.8 5mg QQ客服:1457312923
    乌木叶碱 E-II; Ebenifoline E-II CFN92118 133740-16-6 C48H51NO18 = 929.9 5mg QQ客服:215959384
    Mayteine; Mayteine CFN92119 104736-05-2 C43H49NO18 = 867.9 5mg QQ客服:3257982914

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