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  • 灵芝酸Jb

    Ganoderic acid Jb

    灵芝酸Jb
    产品编号 CFN92997
    CAS编号 112430-68-9
    分子式 = 分子量 C30H46O4 = 470.68
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruit body of Ganoderma lucidum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    灵芝酸Jb CFN92997 112430-68-9 1mg QQ客服:215959384
    灵芝酸Jb CFN92997 112430-68-9 5mg QQ客服:215959384
    灵芝酸Jb CFN92997 112430-68-9 10mg QQ客服:215959384
    灵芝酸Jb CFN92997 112430-68-9 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Aveiro University (Portugal)
  • Technical University of Denmark (Denmark)
  • Copenhagen University (Denmark)
  • University of Queensland (Australia)
  • Instituto de Investigaciones Agropecuarias (Chile)
  • University of Malaya (Malaysia)
  • University of Minnesota (USA)
  • Griffith University (Australia)
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  • Harvard University (USA)
  • Nanjing University of Chinese Medicine (China)
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  • University of Helsinki (Finland)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Curr Issues Mol Biol.2023, ;45(2):1601-1612.
  • Phytomedicine.2018, 38:45-56
  • Universidade Estadual Paulista2017, 42785
  • Food Chem.2018, 252:207-214
  • National University of Pharmacy2022, 1:73-76
  • Biomol Ther (Seoul).2019, 10.4062
  • Cancers (Basel).2021, 13(6):1432.
  • In Vitro Cellular & Developmental Biology - Plant2022, 58:972-988.
  • ScientificWorldJournal.2022, 2022:4806889.
  • Internoational J of Toxicology2020, 10.1177.
  • Biotechnol Bioeng.2020, 117(7):2198-2208.
  • ACS Synth Biol.2020, 9(9):2282-2290.
  • Nutrients.2018, 10(12):E1998
  • J Korean Society of Food Science & Nutrition2021, 50(9): 962-970
  • Planta Med.2023, a-2192-2281.
  • Food Chem Toxicol.2023, 176:113802.
  • Applied Biological Chemistry2023, 66:85.
  • Front Mol Neurosci.2023, 15:1083189.
  • Chemistry of Plant Materials.2019, 215-222
  • Food Chem.2020, 313:126079
  • Tropical J. of Pha. Research2017, 16(3):543-552
  • J Inflamm Res.2022, 15:5347-5359.
  • BMC Complement Med Ther.2023, 23(1):264.
  • ...
  • 生物活性
    Description: Reference standards.
    In vitro:
    Planta Medica, 2012, 78(04):368-376.
    Isolation and Bioactivity Evaluation of Terpenoids from the Medicinal Fungus Ganoderma sinense.[Reference: WebLink]

    METHODS AND RESULTS:
    A new pentanorlanostane, ganosineniol A (1), eight new lanostane triterpenoids, ganosinoside A (2), ganoderic acid Jc (3), ganoderic acid Jd (4), ganodermatetraol (5), ganolucidic acid γa (6), ganolucidate F (7), ganoderiol J ( 8), and methyl lucidenate Ha ( 9), and a new sesquiterpenoid, ganosinensine (10), together with eleven known triterpenoids (11- 21), were isolated from the fruiting bodies of the fungus Ganoderma sinense. Chemical structures were determined based on spectroscopic evidence, including 1D, 2D NMR, and mass spectral data. Furthermore, all isolates were tested for cytotoxic activity and induction ability of hPXR-mediated CYP3A4 expression.
    CONCLUSIONS:
    Among them, ganoderic acid Jc (3) displayed selective inhibitory activity against HL-60 cells (IC₅₀ = 8.30 µM), and ganoderiol E (11) exhibited selective cytotoxic activity against MCF-7 cells (IC₅₀ = 6.35 µM). Meanwhile, compounds 5, 7, and ganolucidic acids B and C (19, 20) showed induction ability of hPXR-mediated CYP3A4 expression.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1246 mL 10.6229 mL 21.2459 mL 42.4917 mL 53.1146 mL
    5 mM 0.4249 mL 2.1246 mL 4.2492 mL 8.4983 mL 10.6229 mL
    10 mM 0.2125 mL 1.0623 mL 2.1246 mL 4.2492 mL 5.3115 mL
    50 mM 0.0425 mL 0.2125 mL 0.4249 mL 0.8498 mL 1.0623 mL
    100 mM 0.0212 mL 0.1062 mL 0.2125 mL 0.4249 mL 0.5311 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    灵芝酸Y; Ganoderic acid Y CFN90294 86377-52-8 C30H46O3 = 454.68 5mg QQ客服:3257982914
    灵芝酸SZ; Ganoderic acid SZ CFN97426 865543-37-9 C30H44O3 = 452.7 5mg QQ客服:215959384
    灵芝酸S; Ganoderic acid S CFN99066 104759-35-5 C30H44O3 = 452.7 5mg QQ客服:3257982914
    灵芝酸TN; Ganoderic acid TN CFN90298 112430-64-5 C32H48O5 = 512.73 5mg QQ客服:215959384
    灵芝酸X; Ganoderic acid X CFN92996 86377-53-9 C32H48O5 = 512.72 5mg QQ客服:215959384
    灵芝酸Jb; Ganoderic acid Jb CFN92997 112430-68-9 C30H46O4 = 470.68 5mg QQ客服:2056216494
    灵芝酸TR; Ganoderic acid TR CFN92235 862893-75-2 C30H44O4 = 468.7 5mg QQ客服:1457312923
    灵芝酸T-Q; Ganoderic acid T-Q CFN92237 112430-66-7 C32H46O5 = 510.7 5 mg QQ客服:215959384
    胭脂虫酸; Coccinic acid CFN99083 107783-45-9 C30H46O3 = 454.7 5mg QQ客服:2056216494
    安五酸; Anwuweizonic acid CFN92727 117020-59-4 C30H46O3 = 454.7 5mg QQ客服:3257982914

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