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  • 圣草酚-7-O-葡萄糖醛酸苷

    Eriodictyol 7-O-glucuronide

    圣草酚-7-O-葡萄糖醛酸苷
    产品编号 CFN95290
    CAS编号 125535-06-0
    分子式 = 分子量 C21H20O12 = 464.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Dracocephalum rupestre
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    圣草酚-7-O-葡萄糖醛酸苷 CFN95290 125535-06-0 1mg QQ客服:215959384
    圣草酚-7-O-葡萄糖醛酸苷 CFN95290 125535-06-0 5mg QQ客服:215959384
    圣草酚-7-O-葡萄糖醛酸苷 CFN95290 125535-06-0 10mg QQ客服:215959384
    圣草酚-7-O-葡萄糖醛酸苷 CFN95290 125535-06-0 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Univerzita Karlova v Praze (Czech Republic)
  • University of East Anglia (United Kingdom)
  • Universidad Industrial de Santander (Colombia)
  • Universidade de Franca (Brazil)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • Michigan State University (USA)
  • Nanjing University of Chinese Medicine (China)
  • Srinakharinwirot University (Thailand)
  • Complutense University of Madrid (Spain)
  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
  • University of Maryland School of Medicine (USA)
  • Universidad de La Salle (Mexico)
  • Universite de Lille1 (France)
  • Wroclaw Medical University (Poland)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Korean Journal of Pharmacognosy2018, 49(4):349-361
  • J Int Med Res.2021, 49(7):3000605211032849.
  • bioRxiv2021, 462065.
  • Chemistry of Plant Materials.2016, 33-46
  • FASEB J.2022, 36(7):e22387.
  • Drug Dev Res.2022, 83(7):1673-1682.
  • Anal Bioanal Chem.2016, 408(1):177-90.
  • Analytical methods2019, 11(6)
  • Planta Med.2019, 85(9-10):766-773
  • J of Apicultural Research2020, 10.1080
  • Molecules.2022, 27(22):7887.
  • Journal of Functional Foods2021, 84:104581
  • J. of The Korean Society of Food Culture2017, 144-149
  • Faculty of Chem. & Nat. Resource Eng.2014, 62
  • Int J Mol Sci.2022, 23(13):7115.
  • Molecules.2019, 25(1):E103
  • Metabolites.2019, 9(11):E271
  • Plant J.2017, 90(3):535-546
  • Molecules.2020, 25(23):5636.
  • J Med Food.2020, 23(6):633-640.
  • Antioxidants.2022, 11(3):592.
  • Foods.2023, 12(12):2412.
  • J Korean Soc Food Sci Nutr2020, doi: 10.3746.
  • ...
  • 生物活性
    Description: Eriodictyol 7-O-glucuronide can be considered as potent inhibitors for DENV NS2B/NS3pro for the development of anti-dengue drugs. Antioxidants.Cytotoxic.
    In vitro:
    Virusdisease . 2016 Sep;27(3):220-225
    Identification of new potent inhibitors of dengue virus NS3 protease from traditional Chinese medicine database[Pubmed: 28466032]
    Dengue virus (DENV) has emerged as an increasing fitness problem in the world for which no specialized drug is available. The non-structural protein NS3 protease of DENV has already been recognized as a potential therapeutic target for the discovery and development of novel antiviral agents against DENV infections. In this study, we employed the virtual screening technique to explore the potent inhibitors of DENV NS2B/NS3pro from Traditional Chinese Medicine (TCM) database. Total 200 inhibitors from TCM against DENV NS3pro were screened and only five TCM compounds like eriodictyol 7-O-glucuronide, luteolin 8-C-beta-glucopyranoside, (-)-epicatechin-3-O-gallate, 6-O-trans-p-coumaroylgeniposide and luteolin-7-O-glucoside were selected for further analysis which showed binding energies, -7.000, -7.380, -7.380, -7.440 and -7.440 kcal/mol, respectively. The findings of this study suggest that these five TCM compounds can be considered as potent inhibitors for DENV NS2B/NS3pro for the development of anti-dengue drugs.
    Int J Mol Sci . 2020 Mar 6;21(5):1828
    JA-Ile-macrolactone 5b Induces Tea Plant ( Camellia sinensis) Resistance to Both Herbivore Ectropis obliqua and Pathogen Colletotrichum camelliae[Pubmed: 32155845]
    Jasmonates (JAs), the group of lipid-derived hormones, were found to control the defense responses in a myriad of plants. Meaningfully, the macrolactones of 12-hydroxy jasmonate isoleucine (12OH-JA-Ile) were reported to induce the defensive response of wild tobacco. However, little to nothing has been known about the elicitation effect of JA-Ile-macrolactones on woody plants to harmful organisms, let alone its underlying mechanisms. Here, we first optimized the synthetic routine using mild toxic reagent isobutyl chloroformate instead of ethyl chloroformate for conjugation, and we used acetonitrile (MeCN) instead of ethyl alcohol for the better dissolution of p-toluenesulfonic acid (p-TsOH) to gain JA-Ile-macrolactones. JA-Ile-macrolactone 5b-treated tea plants significantly inhibited the larvae weight gain of Ectropis obliqua larvae and the lesions caused by Colletotrichum camelliae. Furthermore, the expression level of CsOPR3 was significantly upregulated in 5b-treated leaves. Meanwhile, 5b reduced the accumulation of eriodictyol 7-O-glucuronide (EDG) in tea plants, which was confirmed to promote the growth rate of E. obliqua larvae by artificial diet assay. In conclusion, our study proved that the exogenous application of 5b could induce the tea plant resistance both to herbivore E. obliqua and pathogen C. camelliae, and EDG was identified as one of the secondary metabolites that could influence the growth rate of E. obliqua, but it did not directly influence the infection of C. camelliae in vitro. Further research should be carried out to clarify the mechanism through which 5b induces tea plant resistance to C. camelliae.
    Molecules . 2019 Dec 5;24(24):4457.
    Phytochemical Fingerprinting and In Vitro Bioassays of the Ethnomedicinal Fern Tectaria coadunata (J. Smith) C. Christensen from Central Nepal[Pubmed: 31817382]
    Tectaria coadunata, an ethnomedicinal fern used in Nepal to treat a large number of diseases, has been poorly studied with regard to its phytochemical composition and possible bioactivity. This study was performed with the aim of supporting traditional medicine as a new source of bioactive constituents. Phytochemical compositions of methanol extracts were determined by nuclear magnetic resonance (NMR), liquid chromatography-diode array detector-mass spectrophotometry (LC-DAD-MS), and liquid chromatography-fluorescence-mass spectrometry. Quali-quantitative data revealed large amount of procyanidins, mainly of the A-type, as well as eriodictyol-7-O-glucuronide and luteolin-7-O-glucoronide as main constituents. The antioxidant, cytotoxic, and inhibitory activity of five enzymes that are implicated in human diseases was evaluated for the extract and fractions. High free-radical scavenging activity in 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) assays and inhibitory activities against cholinesterases and tyrosinase were observed. Furthermore, a moderate cytotoxic effect was observed on the 2008 and BxPC3 cell lines. Overall results showed potential usefulness of this fern as a source of phytochemicals for pharmaceutical uses.
    In vivo:
    Nat Prod Commun . 2015 Jun;10(6):937-40.
    Water Extract of Mentha x villosa: Phenolic Fingerprint and Effect on Ischemia-Reperfusion Injury[Pubmed: 26197521]
    Qualitative analysis of the water extract of Mentha x villosa Huds. leaves was performed by liquid chromatography mass spectrometry (LC-MS/MS) and quantitative analysis was made by reverse-phase liquid chromatography coupled with photodiode array detection (LC-DAD). Sixteen phenolic compounds were identified and quantified consisting of 8 phenolic acids/derivatives and 8 flavonoid glycosides (quinic acid, chlorogenic acid, coumaroyl-hexoside, caffeic acid, coumaroylquinic acid, lithospermic acid, rosmarinic acid, salvianolic acid A, luteolin-7-O-glucuronide, luteolin-7-O-glucoside, luteolin-7-O-rutinoside, eriodictyol-7-O-rutinoside, apigenin-7-O-glucuronide, kaempferol-3-O-glucuronide, chrysoeriol-7-O-rutinoside, and hesperetin-7-O-rutinoside). Luteolin-7- O-rutinoside (25.6 ± 0.7 mg/g dry extract) and rosmarinic acid (17.9 ± 0.4 mg/g dry extract) were the most abundant. High antioxidant activity of this phenolic-rich water extract was confirmed in vitro by DPPH and ABTS tests and ex vivo in the ischemia-reperfusion injured rat superior mesenteric artery. Thus, the water extract of M. x villosa leaves seems to be a promising agent in prevention of tissue injury caused by oxidative stress.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1533 mL 10.7666 mL 21.5332 mL 43.0663 mL 53.8329 mL
    5 mM 0.4307 mL 2.1533 mL 4.3066 mL 8.6133 mL 10.7666 mL
    10 mM 0.2153 mL 1.0767 mL 2.1533 mL 4.3066 mL 5.3833 mL
    50 mM 0.0431 mL 0.2153 mL 0.4307 mL 0.8613 mL 1.0767 mL
    100 mM 0.0215 mL 0.1077 mL 0.2153 mL 0.4307 mL 0.5383 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    新北美圣草苷; Neoeriocitrin CFN92304 13241-32-2 C27H32O15 = 596.5 20mg QQ客服:1413575084
    圣草次甙; 圣草次苷; Eriocitrin CFN99718 13463-28-0 C27H32O15 = 596.53 20mg QQ客服:1413575084
    橙皮素7-O-葡萄糖苷; Hesperetin 7-O-glucoside CFN98405 31712-49-9 C22H24O11 = 464.4 10mg QQ客服:215959384
    橙皮苷; Hesperidin CFN98839 520-26-3 C28H34O15 = 610.6 20mg QQ客服:215959384
    3''-O-咖啡酰橙皮苷; 3''-O-Caffeoylhesperidin CFN95564 N/A C37H40O18 = 772.7 5mg QQ客服:215959384
    橙皮素5-O-葡萄糖苷; Hesperetin 5-O-glucoside CFN96023 69651-80-5 C22H24O11 = 464.4 5mg QQ客服:3257982914
    桃苷; Persicoside CFN97908 28978-03-2 C23H26O11 = 478.5 5mg QQ客服:1413575084
    甲基橙皮甙; 甲基橙皮苷; Methyl hesperidin CFN99584 11013-97-1 C29H36O15 = 624.59 20mg QQ客服:1413575084
    地奥司明杂质8; Diosmin Impurity 8 CFN95309 28719-21-3 C30H38O15 = 638.6 10mg QQ客服:1413575084
    (R)-5,3'-二甲基橙皮苷; (R)-5,3'-Dimethyl hesperidin CFN95310 N/A C30H38O15 = 638.6 5mg QQ客服:3257982914

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