三(羟甲基)甲基甘氨酸
Tricine
|
产品编号 |
CFN98511 |
CAS编号 |
5704-04-1 |
分子式 = 分子量 |
C6H13NO5 = 179.17 |
产品纯度 |
>=98% |
物理属性 |
White powder |
化合物类型 |
Miscellaneous |
植物来源 |
The roots of Beta vulgaris |
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 |
|
产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
三(羟甲基)甲基甘氨酸 |
CFN98511 |
5704-04-1 |
10mg |
QQ客服:1413575084 |
三(羟甲基)甲基甘氨酸 |
CFN98511 |
5704-04-1 |
20mg |
QQ客服:1413575084 |
三(羟甲基)甲基甘氨酸 |
CFN98511 |
5704-04-1 |
50mg |
QQ客服:1413575084 |
三(羟甲基)甲基甘氨酸 |
CFN98511 |
5704-04-1 |
100mg |
QQ客服:1413575084 |
1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。
2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。
3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
订购流程
1. 在线订购
请联系我们QQ客服
2. 电话订购
请拨打电话:
027-84237683 或 027-84237783
3. 邮件或传真订购
发送电子邮件到: manager@chemfaces.com 或
发送传真到:027-84254680
提供订购信息
为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
1. 产品编号(CAS No.或产品名称)
2. 发货地址
3. 联系方法 (联系人,电话)
4. 开票抬头 (如果需要发票的客户)
5. 发票地址(发货地址与发票地址不同)
发货时间
1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。
2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。
3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
ChemFaces的产品在许多优秀和顶级科学期刊中被引用
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
Worcester Polytechnic Institute (USA)
Universidade da Beira Interior (Germany)
Universidad de Ciencias y Artes de Chiapas (Mexico)
Seoul National University (Korea)
The Institute of Cancer Research (United Kingdom)
University of Wisconsin-Madison (USA)
Institute of Chinese Materia Medica (China)
Institute of Tropical Disease Universitas Airlangga (Indonesia)
Aarhus University (Denmark)
Utrecht University (Netherlands)
Colorado State University (USA)
University of Helsinki (Finland)
Instituto de Investigaciones Agropecuarias (Chile)
Universita' Degli Studi Di Cagliari (Italy)
More...
国外学术期刊发表的引用ChemFaces产品的部分文献
Description: |
Tricine can clearly visualize tumors, may as melanoma imaging agents. Using the combination of tricine and a phosphine ligand, HYNIC-derivatized peptides or other small molecules can be labeled with 99mTc in high specific activity and with high stability for potential use as radiopharmaceuticals. |
In vitro: |
J. Immunol. Methods,1990 Jan 24;1 26(1):109-17. | Increased resolution of lipopolysaccharides and lipooligosaccharides utilizing tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis.[Pubmed: 2106001] | METHODS AND RESULTS: We utilized the recently described tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis (TSDS-PAGE) system to study the lipooligosaccharides (LOS) and lipopolysaccharides (LPS) of gram negative bacteria. TSDS-PAGE resulted in a high degree of resolution of LOS and LPS in the 'mini-gel' format. TSDS-PAGE resulted in the LOS and LPS migrating as a function of their Mr during electrophoresis and allowed estimation of Mr from a protein standard. Several species of LOS were analyzed. CONCLUSIONS: The newly described procedure allowed a more rapid and accurate analysis of LOS and the core region of LPS. |
|
In vivo: |
Anticancer Agents Med Chem. 2014;15(1):122-30. | Evaluation of tricine and EDDA as Co-ligands for 99mTc-labeled HYNIC-MSH analogs for melanoma imaging.[Pubmed: 25175799 ] | Several radiolabeled alpha-melanocyte stimulating hormone (α-MSH) analogs have been studied for their abilities to target melanoma tumor cells through specific recognition and binding to the melanocortin receptor 1 (MCR1). METHODS AND RESULTS: In this work, a lactam bridgecyclized α-MSH analog was labeled with (99m) via the hydrazinonicotinamide (HYNIC) chelator and characterized for its melanoma tumor targeting properties. The bifunctional chelating agent HYNIC-Boc was attached to the N-terminus of the MSH peptide followed by the lactam cyclization, resulting in the HYNIC-cyc-MSH analog. The lactam cyclized peptide displayed high affinity and specificity for MC1-receptors present on B16/F1 melanoma tumor cells, exhibiting an IC50 of 6.48 nM. HYNIC-cyc-MSH was radiolabeled with (99m)Tc using two common co-ligands, tricine and EDDA. In vitro, the radiochemical stability, cell binding and efflux properties were similar between the peptides radiolabeled with tricine and EDDA as co-ligands. In vivo, biodistribution studies (n=4) demonstrated that (99m)Tc- HYNIC-cyc-MSH/tricine had superior tumor to muscle and tumor to blood ratios than (99m)Tc-HYNIC-cyc-MSH/EDDA at early time points.
CONCLUSIONS:
Planar gamma imaging of melanoma bearing mice showed that 99mTc-HYNIC-cyc-MSH/tricine was able to clearly visualize tumors, underscoring the potential utility of (99m)Tc labeled lactam cyclized MSH molecules as melanoma imaging agents. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
1 mM |
5.5813 mL |
27.9065 mL |
55.8129 mL |
111.6258 mL |
139.5323 mL |
5 mM |
1.1163 mL |
5.5813 mL |
11.1626 mL |
22.3252 mL |
27.9065 mL |
10 mM |
0.5581 mL |
2.7906 mL |
5.5813 mL |
11.1626 mL |
13.9532 mL |
50 mM |
0.1116 mL |
0.5581 mL |
1.1163 mL |
2.2325 mL |
2.7906 mL |
100 mM |
0.0558 mL |
0.2791 mL |
0.5581 mL |
1.1163 mL |
1.3953 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
部分图片展示
联系方式
电机:027-84237783
传真:027-84254680
在线QQ: 1413575084
E-Mail:manager@chemfaces.com
湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房
ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证
天然化合物与对照品的研发和生产。