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  • 草大戟素

    Steppogenin

    草大戟素
    产品编号 CFN98949
    CAS编号 56486-94-3
    分子式 = 分子量 C15H12O6 = 288.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The stems of Cudrania tricuspidata.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    草大戟素 CFN98949 56486-94-3 1mg QQ客服:1413575084
    草大戟素 CFN98949 56486-94-3 5mg QQ客服:1413575084
    草大戟素 CFN98949 56486-94-3 10mg QQ客服:1413575084
    草大戟素 CFN98949 56486-94-3 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universiti Malaysia Pahang (Malaysia)
  • University of the Basque Country (Spain)
  • National Hellenic Research Foundation (Greece)
  • University of Wisconsin-Madison (USA)
  • Griffith University (Australia)
  • Agricultural Research Organization (ARO) (Israel)
  • Max-Planck-Insitut (Germany)
  • University of Stirling (United Kingdom)
  • Heinrich-Heine-University Düsseldorf (Germany)
  • Shanghai Institute of Organic Chemistry (China)
  • University of Madras (India)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • Ain Shams University (Egypt)
  • Macau University of Science and Technology (China)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Nat Prod.2015, 78(6):1339-4
  • Sci Rep.2021, 11(1):10931.
  • Pharmaceutics.2020, 12(9):882.
  • Nutrients.2020, 12(5):1242.
  • J Drug Target.2016, 24:1-28
  • Molecules.2021, 26(9):2791.
  • Food Sci Biotechnol.2023, 32(9):1215-1223.
  • J Clin Med.2019, 8(10):E1664
  • Int. J. of Pha. and Phy. Res.2015, 7(1):144-149
  • Reprod Sci.2022,10.1007/s43032-022-01117-4.
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1126-1127:121743
  • J Cell Mol Med.2020, 24(21):12308-12317.
  • Phytochemistry Letters2021, 43:80-87.
  • Asian Pac J Cancer Prev. 2020, 21(4):935-941.
  • Pharmacognosy Journal2019, 11(2): 369-373
  • Phytomedicine.2015, 22(4):498-503
  • Molecules.2021, 26(6):1635.
  • Braz J Biol.2023, 82:e266573.
  • J Appl Biol Chem2023, 66:455−461
  • Front Plant Sci.2022, 13: 905275.
  • Sci Rep. 2017, 17332(7)
  • Toxicol Mech Methods.2021, 1-12.
  • Asian J Beauty Cosmetol2020, 18(3): 265-272.
  • ...
  • 生物活性
    Description: Steppogenin exhibits significant tyrosinase inhibition activity, it also shows strong mushroom tyrosinase inhibitory activity with IC(50) values lower than 50 microM, more potent than kojic acid (IC(50) = 71.6 microM), a well-known tyrosinase inhibitor.
    Targets: Tyrosinase
    In vitro:
    Mol Nutr Food Res. 2008 Dec;52(12):1530-8.
    Isolation of tyrosinase inhibitors from Artocarpus heterophyllus and use of its extract as antibrowning agent.[Pubmed: 18683821]
    A new furanoflavone, 7-(2,4-dihydroxyphenyl)-4-hydroxy-2-(2-hydroxy propan-2-yl)-2, 3-dihydrofuro(3, 2-g)chromen-5-one (artocarpfuranol, 1), together with 14 known compounds, dihydromorin (2), Steppogenin (3), norartocarpetin (4), artocarpanone (5), artocarpesin (6), artocarpin (7), cycloartocarpin (8), cycloartocarpesin (9), artocarpetin (10), brosimone I (11), cudraflavone B (12), carpachromene (13), isoartocarpesin (14), and cyanomaclurin (15) were isolated from the wood of Artocarpus heterophyllus.
    METHODS AND RESULTS:
    Their structures were identified by interpretation of MS,( 1)H-NMR,( 13)C-NMR, HMQC, and HMBC spectroscopic data. Among them, compounds 1-6 and 14 showed strong mushroom tyrosinase inhibitory activity with IC(50) values lower than 50 microM, more potent than kojic acid (IC(50) = 71.6 microM), a well-known tyrosinase inhibitor. In addition, extract of A. heterophyllus was evaluated for its antibrowning effect on fresh-cut apple slices. It was discovered that fresh-cut apple slices treated by dipping in solution of 0.03 or 0.05% of A. heterophyllus extract with 0.5% ascorbic acid did not undergo any substantial browning reaction after storage at room temperature for 24 h. The antibrowning effect was significantly better than samples treated with the extract (0.03 or 0.05%) or ascorbic acid (0.5%) alone.
    CONCLUSIONS:
    The results provide preliminary evidence supporting the potential of this natural extract as antibrowning agent in food systems.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.4686 mL 17.343 mL 34.6861 mL 69.3722 mL 86.7152 mL
    5 mM 0.6937 mL 3.4686 mL 6.9372 mL 13.8744 mL 17.343 mL
    10 mM 0.3469 mL 1.7343 mL 3.4686 mL 6.9372 mL 8.6715 mL
    50 mM 0.0694 mL 0.3469 mL 0.6937 mL 1.3874 mL 1.7343 mL
    100 mM 0.0347 mL 0.1734 mL 0.3469 mL 0.6937 mL 0.8672 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    5,7,2',6'-四羟基黄烷酮; 2',5,6',7-Tetrahydroxyflavanone CFN97285 80604-16-6 C15H12O6 = 288.3 5mg QQ客服:2056216494
    2',5,6',7-四乙酰氧基黄烷酮; 2',5,6',7-Tetraacetoxyflavanone CFN97286 80604-17-7 C23H20O10 = 456.4 5mg QQ客服:3257982914
    草大戟素; Steppogenin CFN98949 56486-94-3 C15H12O6 = 288.3 5mg QQ客服:1457312923
    3',5,5',7-四羟基黄烷酮; 3',5,5',7-Tetrahydroxyflavanone CFN99673 160436-10-2 C15H12O6 = 288.3 5mg QQ客服:1457312923
    艾纳香素; Blumeatin CFN99278 118024-26-3 C16H14O6 = 302.3 5mg QQ客服:1413575084
    刺槐双氢黄酮; Robtin CFN98672 4382-34-7 C15H12O6 = 288.3 5mg QQ客服:3257982914
    车前子苷; Plantagoside CFN91894 78708-33-5 C21H22O12 = 466.39 5mg QQ客服:2056216494
    3',4',5',5,7-五甲氧基二氢黄酮; 3',4',5',5,7-Pentamethoxyflavanone CFN95414 479672-30-5 C20H22O7 = 374.4 20mg QQ客服:2056216494
    5,7,3'-三羟基-6,4',5'-三甲氧基黄烷酮; 5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavanone CFN98393 310888-07-4 C18H18O8 = 362.3 5mg QQ客服:3257982914
    5,6,7,3',4',5'-六甲氧基二氢黄酮; 5,6,7,3',4',5'-Hexamethoxyflavanone CFN95376 74064-17-8 C21H24O8 = 404.4 10mg QQ客服:3257982914

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