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  • 5,6,7,3',4',5'-六甲氧基二氢黄酮

    5,6,7,3',4',5'-Hexamethoxyflavanone

    5,6,7,3',4',5'-六甲氧基二氢黄酮
    产品编号 CFN95376
    CAS编号 74064-17-8
    分子式 = 分子量 C21H24O8 = 404.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Gardenia sootepensis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    5,6,7,3',4',5'-六甲氧基二氢黄酮 CFN95376 74064-17-8 1mg QQ客服:215959384
    5,6,7,3',4',5'-六甲氧基二氢黄酮 CFN95376 74064-17-8 5mg QQ客服:215959384
    5,6,7,3',4',5'-六甲氧基二氢黄酮 CFN95376 74064-17-8 10mg QQ客服:215959384
    5,6,7,3',4',5'-六甲氧基二氢黄酮 CFN95376 74064-17-8 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Zurich (Switzerland)
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  • Osmania University (India)
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  • Universidade da Beira Interior (Germany)
  • University of Wisconsin-Madison (USA)
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  • Tohoku University (Japan)
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  • Centralised Purchases Unit (CPU), B.I.T.S (India)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Appl. Sci.2021, 11(24),12080
  • Molecules.2016, 21(6)
  • Org Biomol Chem.2017, 15(31):6483-6492
  • Sci Rep.2018, 8(1):12970
  • FASEB J.2019, 33(2):2026-2036
  • Anesth Pain Med (Seoul).2020, 15(4):478-485.
  • Int J Mol Sci.2020, 21(22):8816.
  • Pharmacognosy Magazine2018, 14(56):418-424
  • Food Chem.2021, 360:130063.
  • Plant Archives2020, 2(1),2929-2934
  • Cell Mol Biol(Noisy-le-grand)2019, 65(7):77-83
  • The Pharmaceutical Society of Japan2018, 138(4):571-579
  • Molecules.2018, 23(9):E2121
  • Nat Prod Sci.2016, 22(2)
  • J of the Korean Society of Food Science and Nutrition2019, 32(2):148-154
  • Plants (Basel).2021, 10(11):2525.
  • Front Pharmacol.2016, 7:460
  • Separations2021, 8(7),90.
  • Environ Toxicol Pharmacol.2019, 66:109-115
  • Mol Cells.2015, 38(9):765-72
  • Enzyme Microb Technol.2019, 122:64-73
  • Cell Prolif.2021, 54(8):e13083.
  • Biomed Chromatogr.2016, 30(10):1573-81
  • ...
  • 生物活性
    Description: 5,6,7,3',4',5'-hexamethoxyflavone has antiproliferative activity against four human cancer cell lines (Aspc-1, HCT-116, HepG-2 and SUN-5).
    In vitro:
    Nat Prod Res . 2021 Aug 5;1-6.
    Synthesis and anti-proliferative activities of 5,6,7-trimethoxyflavones and their derivatives[Pubmed: 34353180]
    A series of 5,6,7-trimethoxyflavones 1a-1g and their derivatives 2a-2g, 3a-3d, 4 and 5, including the natural products 5,6,7-trimethoxy-4'-hydroxyflavone (1a), 5,6,7,3',4' -pentamethoxyflavone (sinensetin, 1 b), 5,6,7-trimethoxy-3',4'-methyl enedioxy flavone (1c), 5,6,7,3'-tetramethoxy-4,5'-methylenedioxyflavone (1e), 5,6,7, 3',4',5'-hextamethoxyflavone (1 g), 5-hydroxy-3,4,2',3',4'-pentamethoxy chal-cone (2 b), 5,4'-dihydroxy-6,7-dimethoxy flavone (cirsimaritin, 3a) and 5-hydroxy-6,7,3', 4'-tetramethoxyflavone (5-demethylsinensetin, 3 b), 3,5,6,7,3',4'-hexamethoxyflavone (3-methoxysinensetin, 4) and 5'-hydroxy-3,6,7,3',4'-pentamethoxyflavone (5) were synthesized. Their anti-proliferative activity in vitro was evaluated against a panel of four human cancer cell lines (Aspc-1, HCT-116, HepG-2 and SUN-5) by the CTG assay. The results showed that most of the synthetic compounds exhibited moderate to high anti-proliferative activities. In particular, compound 3c possess IC50 (5.30 μM) values below 10 μM against Aspc-1 cells and are worthy of further investigation.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.4728 mL 12.364 mL 24.728 mL 49.456 mL 61.82 mL
    5 mM 0.4946 mL 2.4728 mL 4.9456 mL 9.8912 mL 12.364 mL
    10 mM 0.2473 mL 1.2364 mL 2.4728 mL 4.9456 mL 6.182 mL
    50 mM 0.0495 mL 0.2473 mL 0.4946 mL 0.9891 mL 1.2364 mL
    100 mM 0.0247 mL 0.1236 mL 0.2473 mL 0.4946 mL 0.6182 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    5,7,2',6'-四羟基黄烷酮; 2',5,6',7-Tetrahydroxyflavanone CFN97285 80604-16-6 C15H12O6 = 288.3 5mg QQ客服:2159513211
    2',5,6',7-四乙酰氧基黄烷酮; 2',5,6',7-Tetraacetoxyflavanone CFN97286 80604-17-7 C23H20O10 = 456.4 5mg QQ客服:1148253675
    草大戟素; Steppogenin CFN98949 56486-94-3 C15H12O6 = 288.3 5mg QQ客服:2932563308
    3',5,5',7-四羟基黄烷酮; 3',5,5',7-Tetrahydroxyflavanone CFN99673 160436-10-2 C15H12O6 = 288.3 5mg QQ客服:1413575084
    艾纳香素; Blumeatin CFN99278 118024-26-3 C16H14O6 = 302.3 5mg QQ客服:2932563308
    刺槐双氢黄酮; Robtin CFN98672 4382-34-7 C15H12O6 = 288.3 5mg QQ客服:215959384
    车前子苷; Plantagoside CFN91894 78708-33-5 C21H22O12 = 466.39 5mg QQ客服:1148253675
    3',4',5',5,7-五甲氧基二氢黄酮; 3',4',5',5,7-Pentamethoxyflavanone CFN95414 479672-30-5 C20H22O7 = 374.4 20mg QQ客服:1148253675
    5,7,3'-三羟基-6,4',5'-三甲氧基黄烷酮; 5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavanone CFN98393 310888-07-4 C18H18O8 = 362.3 5mg QQ客服:3257982914
    5,6,7,3',4',5'-六甲氧基二氢黄酮; 5,6,7,3',4',5'-Hexamethoxyflavanone CFN95376 74064-17-8 C21H24O8 = 404.4 10mg QQ客服:215959384

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