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  • Sativan

    Sativan

    Sativan
    产品编号 CFN96501
    CAS编号 71831-00-0
    分子式 = 分子量 C17H18O4 = 286.32
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Trifolium pratense L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Sativan CFN96501 71831-00-0 1mg QQ客服:1413575084
    Sativan CFN96501 71831-00-0 5mg QQ客服:1413575084
    Sativan CFN96501 71831-00-0 10mg QQ客服:1413575084
    Sativan CFN96501 71831-00-0 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Sapienza University of Rome (Italy)
  • Monash University Sunway Campus (Malaysia)
  • John Innes Centre (United Kingdom)
  • Korea Intitute of Science and Technology (KIST) (Korea)
  • University of Toronto (Canada)
  • Johannes Gutenberg University Mainz (JGU) (Germany)
  • Chiang Mai University (Thailand)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • Calcutta University (India)
  • University of Brasilia (Brazil)
  • Michigan State University (USA)
  • Chulalongkorn University (Thailand)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Nanjing University of Chinese Medicine (China)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Cell Signal.2022, 99:110433.
  • Front Cell Dev Biol.2021, 9:764263.
  • Nutrients.2021, 13(8):2901.
  • Evid Based Complement Alternat Med.2021, 2021:8850744.
  • Food Chemistry2023, 137837.
  • Molecules.2019, 24(2):329
  • Analytical Letters 2021, 54(4).
  • Int J Vitam Nutr Res.2022, doi: 10.1024.
  • Molecules2022, 27(12):3824.
  • Food Structure2023, 36:100324.
  • Phytomedicine.2016, 23(4):331-9
  • Molecules.2020, 25(17):3783.
  • Molecules.2019, 24(2):E343
  • bioRxiv2021, 458409.
  • Molecules2021, 26(1),230
  • Biomed Pharmacother.2019, 111:262-269
  • Oncotarget.2017, 8(64):108006-108019
  • University of Central Lancashire2017, 20472
  • Arch Pharm Res.2015, 38(6):1080-9
  • Biomolecules2021, 11(10),1513.
  • Chinese Journal of Hospital Pharmacy2020, 40(7)
  • Auburn University2015, 1-58
  • J Cell Biochem.2022, 123(7):1222-1236.
  • ...
  • 生物活性
    Description: Sativan possesses a broad spectrum of antimicrobial activity against bacteria and phytopathogenic fungi, it exhibits antituberculosis activity against Mycobacterium tuberculosis H37Rv, with the MIC value of 50 ug/mL.
    Targets: Antifection
    In vitro:
    Pharmaceuticals (Basel). 2012 Aug 23;5(8):882-9.
    The Chemical Components of Sesbania grandiflora Root and Their Antituberculosis Activity.[Pubmed: 24280680 ]

    METHODS AND RESULTS:
    Three isoflavanoids, isovestitol (1), medicarpin (2), and sativan (3), along with another known compound, betulinic acid (4), were isolated from the root of Sesbania grandiflora. The structures of the isolated compounds were characterised by means of spectroscopic techniques (UV, IR, MS, 1H- and 13C-NMR, DEPT, COSY, HMQC, HMBC, and MS analysis).
    CONCLUSIONS:
    All the tested compounds 1-4 exhibited antituberculosis activity against Mycobacterium tuberculosis H37Rv, with MIC values of 50 µg/mL for compounds 1-3, and 100 µg/mL for compound 4, whereas, the methanol extract exhibited antituberculosis activity of 625 µg/mL. This is the first report on the occurrence of isoflavonoids in this plant and their antituberculosis activity.
    Antimicrob Agents Chemother. 1980 Feb;17(2):120-3.
    Susceptibility of zoopathogenic fungi to phytoalexins.[Pubmed: 7387136 ]
    Phytoalexins are a group of low-molecular-weight antibiotics produced by higher plants in response to infection by relatively avirulent microorganisms. They are of relatively low toxicity for mammalian cells and have been reported to possess a broad spectrum of antimicrobial activity against bacteria and phytopathogenic fungi.
    METHODS AND RESULTS:
    Employing a broth dilution technique, we have found the zoopathogens Petriellidium boydii, Aspergillus flavus, A. fumigatus, Candida albicans, Coccidioides immitis, Cryptococcus neoformans, Histoplasma capsulatum, Rhizopus oryzae, Sporothrix schenckii, and Trichophyton rubrum to be inhibited by one or more of the phytoalexins maackiain, medicarpin, phaseollin, phaseollin isoflavan, pisatin, Sativan, and vestitol in concentrations of from 12.5 to 50 microgram/ml. Phaseollin isofalvan was the most effective of these.
    CONCLUSIONS:
    In agar cup diffusion tests growth of the yeast form of Blastomyces dermatitidis was inhibited by phaseollin at 50 microgram/ml and by phaseollin isoflavan at 25 microgram/ml. Susceptibility of the mycelial form of B. dermatitidis to these two compounds was demonstrated by inhibition of radial extension on agar plates.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.4926 mL 17.463 mL 34.926 mL 69.8519 mL 87.3149 mL
    5 mM 0.6985 mL 3.4926 mL 6.9852 mL 13.9704 mL 17.463 mL
    10 mM 0.3493 mL 1.7463 mL 3.4926 mL 6.9852 mL 8.7315 mL
    50 mM 0.0699 mL 0.3493 mL 0.6985 mL 1.397 mL 1.7463 mL
    100 mM 0.0349 mL 0.1746 mL 0.3493 mL 0.6985 mL 0.8731 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Mucronulatol; Mucronulatol CFN95386 20878-98-2 C17H18O5 = 302.3 5mg QQ客服:2159513211
    3',8-二羟基驴食草酚; 3',8-Dihydroxyvestitol CFN95384 122587-87-5 C16H16O6 = 304.3 5mg QQ客服:1413575084
    光甘草定; Glabridin CFN99731 59870-68-7 C20H20O4 = 324.37 20mg QQ客服:3257982914
    Neorauflavane; Neorauflavane CFN97919 53734-74-0 C21H22O5 = 354.4 5mg QQ客服:3257982914
    Neorauflavene; Neorauflavene CFN97981 53734-75-1 C21H20O5 = 352.4 5mg QQ客服:1413575084
    粗毛甘草素D; Glyasperin D CFN96523 142561-10-2 C22H26O5 = 370.44 5mg QQ客服:2056216494
    去氢粗毛甘草素 D; Dehydroglyasperin D CFN96516 517885-72-2 C22H24O5 = 368.42 5mg QQ客服:2056216494
    垂崖豆藤异黄烷醌; Pendulone CFN91031 69359-09-7 C17H16O6 = 316.31 5mg QQ客服:215959384
    7,2'-羟基-3',4'-二甲氧基异黄烷; Isomucronulatol CFN90839 52250-35-8 C17H18O5 = 302.3 10mg QQ客服:2056216494
    黄芪异黄烷苷; Isomucronulatol 7-O-glucoside CFN93256 94367-43-8 C23H28O10 = 464.5 20mg QQ客服:1457312923

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