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  • 3',8-二羟基驴食草酚

    3',8-Dihydroxyvestitol

    3',8-二羟基驴食草酚
    产品编号 CFN95384
    CAS编号 122587-87-5
    分子式 = 分子量 C16H16O6 = 304.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Lotus corniculatus L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    3',8-二羟基驴食草酚 CFN95384 122587-87-5 1mg QQ客服:2932563308
    3',8-二羟基驴食草酚 CFN95384 122587-87-5 5mg QQ客服:2932563308
    3',8-二羟基驴食草酚 CFN95384 122587-87-5 10mg QQ客服:2932563308
    3',8-二羟基驴食草酚 CFN95384 122587-87-5 20mg QQ客服:2932563308
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Appl. Sci.2020, 10(23), 8729
  • Food Res Int.2020, 133:109130.
  • Chin J Appl. Physiol.2019, 35(3):283-288
  • Horticulture Research2020, 7:111.
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  • Front Pharmacol.2020, 11:683.
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  • Journal of Ginseng Research2021, 3 June.
  • Academic J of Second Military Medical University2019, 40(1)
  • J Ginseng Res.2022, 46(1):104-114.
  • Molecules.2018, 23(12):E3103
  • Metabolites.2019, 9(11):E271
  • Pharmaceutics.2021, 13(2):187.
  • Plants (Basel).2021, 10(2):278.
  • Asian J Beauty Cosmetol2019, 17(3):287-294
  • Crystals2020, 10(3), 206.
  • Cell Chem Biol.2019, 26(1):27-34
  • Phytochemistry.2017, 141:162-170
  • ...
  • 生物活性
    Description: 3',8-Dihydroxyvestitol could serve as antiviral drugs for dengue infection.
    In vitro:
    Bioinformation . 2014 Jul 22;10(7):460-465.
    Molecular Docking Based Screening of Plant Flavonoids as Dengue NS1 Inhibitors[Pubmed: 25187688]
    Dengue infection has turned into a serious health concern globally due to its high morbidity rate and a high possibility of increase in its mortality rate on the account of unavailability of any proper treatment for severe dengue infection. The situation demands an urgent development of efficient and practicable treatment to deal with Dengue virus (DENV). Flavonoids, a class of phytochemicals present in medicinal plants, possess anti-viral activity and can be strong drug candidates against viruses. NS1 glycoprotein of Dengue virus is involved in its RNA replication and can be a strong target for screening of drugs against this virus. Current study focuses on the identification of flavonoids which can block Asn-130 glycosylation site of Dengue virus NS1 to inhibit viral replication as glycosylation of NS1 is required for its biological functioning. Molecular docking approach was used in this study and the results revealed that flavonoids have strong potential interactions with active site of NS1. Six flavonoids (Deoxycalyxin A; 3,5,7,3',4'-pentahydroxyflavonol-3-O-beta-D-galactopyranoside; (3R)-3',8-Dihydroxyvestitol; Sanggenon O; Epigallocatechin gallate; Chamaejasmin) blocked the Asn-130 glycosylation site of NS1 and could be able to inhibit the viral replication. It can be concluded from this study that these flavonoids could serve as antiviral drugs for dengue infections. Further in-vitro analyses are required to confirm their efficacy and to evaluate their drug potency.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.2862 mL 16.4312 mL 32.8623 mL 65.7246 mL 82.1558 mL
    5 mM 0.6572 mL 3.2862 mL 6.5725 mL 13.1449 mL 16.4312 mL
    10 mM 0.3286 mL 1.6431 mL 3.2862 mL 6.5725 mL 8.2156 mL
    50 mM 0.0657 mL 0.3286 mL 0.6572 mL 1.3145 mL 1.6431 mL
    100 mM 0.0329 mL 0.1643 mL 0.3286 mL 0.6572 mL 0.8216 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    3',8-二羟基驴食草酚; 3',8-Dihydroxyvestitol CFN95384 122587-87-5 C16H16O6 = 304.3 5mg QQ客服:215959384
    光甘草定; Glabridin CFN99731 59870-68-7 C20H20O4 = 324.37 20mg QQ客服:2932563308
    Neorauflavane; Neorauflavane CFN97919 53734-74-0 C21H22O5 = 354.4 5mg QQ客服:1148253675
    Neorauflavene; Neorauflavene CFN97981 53734-75-1 C21H20O5 = 352.4 5mg QQ客服:1148253675
    粗毛甘草素D; Glyasperin D CFN96523 142561-10-2 C22H26O5 = 370.44 5mg QQ客服:1413575084
    去氢粗毛甘草素 D; Dehydroglyasperin D CFN96516 517885-72-2 C22H24O5 = 368.42 5mg QQ客服:1413575084
    垂崖豆藤异黄烷醌; Pendulone CFN91031 69359-09-7 C17H16O6 = 316.31 5mg QQ客服:1148253675
    7,2'-羟基-3',4'-二甲氧基异黄烷; Isomucronulatol CFN90839 52250-35-8 C17H18O5 = 302.3 10mg QQ客服:2932563308
    黄芪异黄烷苷; Isomucronulatol 7-O-glucoside CFN93256 94367-43-8 C23H28O10 = 464.5 10mg QQ客服:215959384
    鱼鳔槐氢醌; Colutehydroquinone CFN91022 181311-16-0 C18H20O6 = 332.35 10mg QQ客服:1148253675

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