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  • 齿孔酸; 齿孔菌酸

    • 齿孔酸; 齿孔菌酸

    Eburicoic acid

    齿孔酸; 齿孔菌酸
    		产品编号 CFN90414
    CAS编号 560-66-7
    分子式 = 分子量 C31H50O3 = 470.73
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The roots of Wolfiporia cocos (Schw.) Ryv.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    齿孔酸; 齿孔菌酸 CFN90414 560-66-7 1mg QQ客服：2056216494
    齿孔酸; 齿孔菌酸 CFN90414 560-66-7 5mg QQ客服：2056216494
    齿孔酸; 齿孔菌酸 CFN90414 560-66-7 10mg QQ客服：2056216494
    齿孔酸; 齿孔菌酸 CFN90414 560-66-7 20mg QQ客服：2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • University of Pretoria (South Africa)
  • Sanford Burnham Medical Research Institute (USA)
  • Universiti Malaysia Pahang (Malaysia)
  • Universidade do Porto (Portugal)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Utrecht University (Netherlands)
  • Universidad de La Salle (Mexico)
  • Universidade da Beira Interior (Germany)
  • University of Bordeaux (France)
  • University of Amsterdam (Netherlands)
  • Korea Institute of Oriental Medicine (Korea)
  • University of Stirling (United Kingdom)
  • University of Madras (India)
  • Charles Sturt University (Denmark)
  • More...
    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Phytother Res.2019, 33(4):1104-1113
  • Front Pharmacol.2020, 11:683.
  • Molecules.2017, 22(2)
  • Pharmacogn Mag.2015, 11:S585-91
  • Sci Rep.2019, 9(1):4646
  • Biol Pharm Bull.2018, 41(11):1645-1651
  • The Korea Journal of Herbology2016, 29-35
  • Molecules.2019, 24(4):E709
  • Applied Biological Chemistry2020, 63:33(2020)
  • Cells.2022, 11(8), 1311.
  • Life Sci.2018, 209:498-506
  • J Chromatogr B Analyt Technol Biomed Life Sci.2020, 1149:122123.
  • J Med Food.2019, 22(10):1067-1077
  • Cell Prolif.2021, 54(8):e13083.
  • The Pharmaceutical Society of Japan2018, 138(4):571-579
  • Comparative Clinical Pathology 2021, 30:961-971.
  • Anticancer Res.2021, 41(3):1357-1364.
  • The Journal of Internal Korean Medicine2015, 36(4):486-497
  • Phytochemistry.2021, 181:112539.
  • Advances in Traditional Medicine 2021, 21:779-789.
  • Neurotox Res.2022, 40(6):1937-1947.
  • JPC-Journal of Planar Chromatography 2017, 30(4)
  • Process Biochemistry2019, 87:213-220
  • ...
    • 生物活性
    Description: Eburicoic acid and TR2 have anti-inflammatory activity, the mechanism is related to the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity, they protect the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms. Eburicoic acid has significant anti-liver cancer effects and more distinctive mechanisms.
    Targets: SOD | NO | TNF-α | NOS | COX | P450 (e.g. CYP17) | IL Receptor
    In vivo:
    J Agric Food Chem. 2013 May 29;61(21):5064-71.
    Analgesic and anti-inflammatory bioactivities of eburicoic acid and dehydroeburicoic acid isolated from Antrodia camphorata on the inflammatory mediator expression in mice.[Pubmed: 23495748 ]
    Eburicoic acid (TR1) and dehydroEburicoic acid (TR2), an active ingredient from Antrodia camphorata (AC) solid-state culture, were evaluated for analgesic and anti-inflammatory effects.
    METHODS AND RESULTS:
    Treatment with Eburicoic acid and TR2 significantly inhibited a number of acetic acid-induced writhing responses and formalin-induced pain in the late phase. In the anti-inflammatory test, Eburicoic acid and TR2 decreased paw edema at the fourth and fifth hour after λ-carrageenan (Carr) administration and increased the activities of catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPx) in the paw edema tissue. We also demonstrated that Eburicoic acid and TR2 significantly attenuated the malondialdehyde (MDA), nitric oxide (NO), tumor necrosis factor (TNF-α), and interleukin-1β (IL-1β) levels in either edema paw or serum at the fifth hour after Carr injection. Western blotting revealed that Eburicoic acid and TR2 decreased Carr-induced inducible nitric oxide synthase (iNOS) and cycloxyclase (COX-2) expressions at the fifth hour in paw edema. Treatment with TR1 and TR2 also diminished neutrophil infiltration into the paw edema at the fifth hour.
    CONCLUSIONS:
    The present study suggests that the anti-inflammatory mechanisms of Eburicoic acid and TR2 might be related to the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1244 mL 10.6218 mL 21.2436 mL 42.4872 mL 53.109 mL
    5 mM 0.4249 mL 2.1244 mL 4.2487 mL 8.4974 mL 10.6218 mL
    10 mM 0.2124 mL 1.0622 mL 2.1244 mL 4.2487 mL 5.3109 mL
    50 mM 0.0425 mL 0.2124 mL 0.4249 mL 0.8497 mL 1.0622 mL
    100 mM 0.0212 mL 0.1062 mL 0.2124 mL 0.4249 mL 0.5311 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    16-O-Acetylpolyporenic acid C; 16-O-Acetylpolyporenic acid C CFN96159 2535-06-0 C33H48O5 = 524.7 5mg QQ客服：2159513211
    6α-羟基猪苓酸C; 6alpha-Hydroxypolyporenic acid C CFN92741 24513-63-1 C31H46O5 = 498.7 5mg QQ客服：3257982914
    新化合物15; New compound 15 CFN95413 N/A C31H46O6 = 514.7 5mg QQ客服：2056216494
    茯苓新酸A; Poricoic acid A(F) CFN92838 137551-38-3 C31H46O5 = 498.7 20mg QQ客服：1413575084
    茯苓酸AM; Poricoic acid AM CFN91538 151200-92-9 C32H48O5 = 512.7 5mg QQ客服：2159513211
    Poricoic acid AE ; Poricoic acid AE CFN96980 1159753-88-4 C33H50O5 = 526.75 5mg QQ客服：1413575084
    24(31)-Dehydrocarboxyacetylquercinic acid; 24(31)-Dehydrocarboxyacetylquercinic acid CFN96179 127970-62-1 C34H50O7 = 570.8 5mg QQ客服：215959384
    齿孔酸; 齿孔菌酸; Eburicoic acid CFN90414 560-66-7 C31H50O3 = 470.73 10mg QQ客服：3257982914
    土莫酸; Tumulosic acid CFN95399 508-24-7 C31H50O4 = 486.7 5mg QQ客服：3257982914
    茯苓酸； 茯灵酸; Pachymic acid CFN99590 29070-92-6 C33H52O5 = 528.76 20mg QQ客服：3257982914

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