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  • 4'-Hydroxy-5,7,3'-trimethoxyflavone

    4'-Hydroxy-5,7,3'-trimethoxyflavone

    4'-Hydroxy-5,7,3'-trimethoxyflavone
    产品编号 CFN95398
    CAS编号 1239-68-5
    分子式 = 分子量 C18H16O6 = 328.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Callicarpa bodinieri
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    4'-Hydroxy-5,7,3'-trimethoxyflavone CFN95398 1239-68-5 1mg QQ客服:1148253675
    4'-Hydroxy-5,7,3'-trimethoxyflavone CFN95398 1239-68-5 5mg QQ客服:1148253675
    4'-Hydroxy-5,7,3'-trimethoxyflavone CFN95398 1239-68-5 10mg QQ客服:1148253675
    4'-Hydroxy-5,7,3'-trimethoxyflavone CFN95398 1239-68-5 20mg QQ客服:1148253675
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Otago (New Zealand)
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  • Cancer Research Initatives Foundation(CARIF) (Malaysia)
  • Michigan State University (USA)
  • Universidad de Ciencias y Artes de Chiapas (Mexico)
  • Kazusa DNA Research Institute (Japan)
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  • University of Minnesota (USA)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Molecules.2018, 23(10):E2638
  • Anal Biochem.2019, 569:10-15
  • Biomed Chromatogr.2019, 8:e4774
  • Molecules 2021, 26(4),1092.
  • Preprints2021, doi:10.20944
  • Front Microbiol.2020, 11:583594.
  • Int J Mol Sci.2021, 22(19):10220.
  • Plants (Basel).2021, 10(2):278.
  • Genes Genomics.2020, 10.1007
  • Institut Pasteur Korea2020, doi: 10.21203.
  • Oncotarget.2016, 8(51):88386-88400
  • J Pharmaceut Biomed2020, 182:113110
  • Front Immunol.2017, 8:1542
  • Food Chem.2019, 290:286-294
  • Toxins (Basel).2021, 13(9):593.
  • J Pharmacol Sci.2021, 147(2):184-191.
  • Antioxidants.2022, 11(3):491.
  • Korean J of Pharmacognosy2020, 51,49-54.
  • Asian J Beauty Cosmetol2016, 14(3):249-257
  • Antiviral Res.2021, 193:105142.
  • Oncotarget.2017, 8(53):90925-90947
  • J Food Sci Technol.2019, 56(5):2712-2720
  • J Nat Med.2022, 76(1):59-67.
  • ...
  • 生物活性
    In vivo:
    J Agric Food Chem . 2012 Aug 22;60(33):8123-8128.
    Identification of 5,7,3',4'-tetramethoxyflavone metabolites in rat urine by the isotope-labeling method and ultrahigh-performance liquid chromatography-electrospray ionization-mass spectrometry[Pubmed: 22812915]
    5,7,3',4'-Tetramethoxyflavone (TMF), one of the major polymethoxyflavones (PMFs) isolated from Kaempferia parviflor , has been reported possessing various bioactivities, including antifungal, antimalarial, antimycobacterial, and anti-inflammatory activities. Although several studies on the TMF have been reported, the information about the metabolism of TMF and the structures of TMF metabolites is still not yet clear. In this study, an isotope-labeling method was developed for the identification of TMF metabolites. Three isotope-labeled TMFs (5,7,3',4'-tetramethoxy[3'-D(3)]flavone, 5,7,3',4'-tetramethoxy[4'-D(3)]flavone, and 5,7,3',4'-tetramethoxy[5,4'-D(6)]flavone) were synthesized and administered to rats. The urine samples were collected, and the main metabolites were monitored by ultrahigh-performance liquid chromatography-electrospray ionization-mass spectrometry. Five TMF metabolites were unambiguously identified as 3'-hydroxy-5,7,4'-trimethoxyflavone, 7-hydroxy-5,3',4'-trimethoxyflavone sulfate, 7-hydroxy-5,3',4'-trimethoxyflavone, 4'-hydroxy-5,7,3'-trimethoxyflavone, and 5-hydroxy-7,3',4'-trimethoxyflavone.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.046 mL 15.23 mL 30.4599 mL 60.9199 mL 76.1499 mL
    5 mM 0.6092 mL 3.046 mL 6.092 mL 12.184 mL 15.23 mL
    10 mM 0.3046 mL 1.523 mL 3.046 mL 6.092 mL 7.615 mL
    50 mM 0.0609 mL 0.3046 mL 0.6092 mL 1.2184 mL 1.523 mL
    100 mM 0.0305 mL 0.1523 mL 0.3046 mL 0.6092 mL 0.7615 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    3',4',7-三羟基黄酮; 7,3',4'-Trihydroxyflavone CFN97786 2150-11-0 C15H10O5 = 270.24 20mg QQ客服:215959384
    3',4',7,8-四羟基黄酮; 3',4',7,8-Tetrahydroxyflavone CFN70342 3440-24-2 C15H10O6 = 286.2 5mg QQ客服:1413575084
    木犀草素; 3',4',5,7-四羟基黄酮; Luteolin CFN98784 491-70-3 C15H10O6 = 286.2 20mg QQ客服:2159513211
    羟基芫花素; Hydroxygenkwanin CFN98021 20243-59-8 C16H12O6 = 300.3 20mg QQ客服:2159513211
    5,7-二甲氧基木犀草素; 5,7-Dimethoxyluteolin CFN91001 N/A C17H14O6 = 314.3 10mg QQ客服:1413575084
    5,6,3',4'-四羟基-7-甲氧基黄酮; Pedalitin CFN96045 22384-63-0 C16H12O7 = 316.3 5mg QQ客服:2932563308
    泽兰黄酮; 6-甲氧基藤黄菌素; 6-Methoxyluteolin CFN92706 520-11-6 C16H12O7 = 316.3 10mg QQ客服:3257982914
    条叶蓟素; Cirsiliol CFN96508 34334-69-5 C17H14O7 = 330.29 5mg QQ客服:1148253675
    Leucanthogenin; Leucanthogenin CFN92953 99615-00-6 C17H14O8 = 346.29 5mg QQ客服:1413575084
    毒马草黄酮; Sideritoflavone CFN96399 70360-12-2 C18H16O8 = 360.3 5mg QQ客服:2932563308

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