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  • 2-氧代果树酸; 2-氧代坡模醇酸

    2-Oxopomolic acid

    2-氧代果树酸; 2-氧代坡模醇酸
    产品编号 CFN98920
    CAS编号 54963-52-9
    分子式 = 分子量 C30H46O5 = 486.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The herbs of Rosa banksiae
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    2-氧代果树酸; 2-氧代坡模醇酸 CFN98920 54963-52-9 1mg QQ客服:215959384
    2-氧代果树酸; 2-氧代坡模醇酸 CFN98920 54963-52-9 5mg QQ客服:215959384
    2-氧代果树酸; 2-氧代坡模醇酸 CFN98920 54963-52-9 10mg QQ客服:215959384
    2-氧代果树酸; 2-氧代坡模醇酸 CFN98920 54963-52-9 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universidade Católica Portuguesa (Portugal)
  • Heidelberg University (Germany)
  • Siksha O Anusandhan University (India)
  • Auburn University (USA)
  • Shanghai Institute of Biochemistry and Cell Biology (China)
  • University of Wuerzburg (Germany)
  • University of Beira Interior (Portugal)
  • Universidade Federal de Santa Catarina (Brazil)
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  • University of Hawaii Cancer Center (USA)
  • Sanford Burnham Medical Research Institute (USA)
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  • Univerzita Karlova v Praze (Czech Republic)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Biomol Ther (Seoul).2019, 10.4062
  • Pharmacognosy Journal2019, 11,6:1235-1241
  • Journal of Oil Palm Research2019, 31(2):238-247
  • Pharmaceuticals (Basel).2021, 14(3):260.
  • Chem Biol Interact.2016, 258:59-68
  • University of Stuttgart2021, 11682.
  • J Cell Mol Med . 2023, jcmm.17954.
  • Sci Rep.2018, 8:9267
  • Sci Rep.2017, 7:46299
  • Sci Rep.2019, 9(1):4646
  • Sci Rep. 2017, 12953(7)
  • FASEB J.2019, 33(2):2026-2036
  • Processes2021, 9(11),2065.
  • Int. J. of Pha. and Phy. Res.2015, 7(1):144-149
  • Asian Journal of Chemistry2014, 26(8):2425
  • J. Soc. Cosmet. Sci. Korea2021, 47(1):57-63
  • Horticulturae2021, 7(1),5.
  • Food Structure2023, 36:100324.
  • J Agric Food Chem.2018, 66(1):351-358
  • Antioxidants (Basel).2020, 9(7):581.
  • Molecules.2021, 26(4):817.
  • J Nat Med.2017, 71(4):745-756
  • Sci Rep.2016, 6:25094
  • ...
  • 生物活性
    Description: 2-Oxopomolic acid shows cytotoxic activity, it shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin. 2-Oxopomolic acid shows radical-scavenging activities similar to that of the reference antioxidant alpha-tocopherol (vitamin E).
    Targets: Immunology & Inflammation related
    In vitro:
    Planta Med. 2000 Jun;66(5):483-4.
    Cytotoxic triterpene acids from the Peruvian medicinal plant Polylepis racemosa.[Pubmed: 10909276]

    METHODS AND RESULTS:
    Cytotoxicity-guided fractionation of the bark and stem extract of Polylepis racemosa led to the identification of ursolic acid, pomolic acid, 3-O-acetylpomolic acid, and 2-oxopomolic acid. Pomolic acid was the most cytotoxic component, and was specific for M-14 melanoma and ME180 cervical carcinoma, with GI50 values of 6.9 and 8.3 micrograms/mL respectively.
    Chem Biodivers. 2005 Jul;2(7):953-8.
    Radical-scavenging activities of new hydroxylated ursane triterpenes from cv. Annurca apples.[Pubmed: 17193186]

    METHODS AND RESULTS:
    Two new ursolic acid triterpene derivatives, compounds 2 and 3, have been isolated from cv. Annurca apple fruit, a high-quality apple variety widely cultivated in southern Italy, together with the known 2-Oxopomolic acid (1). The new compounds were identified by means of different spectroscopic techniques as 3-epi-2-Oxopomolic acid (= (3alpha)-3,19-dihydroxy-2-oxours-12-en-28-oic acid; 2) and (1alpha)-1-hydroxy-3-oxours-12-en-28-oic acid (3). Compounds 1-3 were tested for their radical-scavenging activities with the aid of a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay (Fig. 2).
    CONCLUSIONS:
    All three constituents showed activities similar to that of the reference antioxidant alpha-tocopherol (vitamin E).
    Nat Prod Res. 2013;27(23):2219-23.
    Triterpenoids from Fragaria ananassa calyx and their inhibitory effects on melanogenesis in B16-F10 mouse melanoma cells.[Pubmed: 23772756 ]

    METHODS AND RESULTS:
    Column chromatographic technology was applied to isolate six purified ursane triterpenoids from the calyx of Fragaria ananassa and they were identified on the basis of spectroscopic methods to be ursolic acid (1), pomolic acid (2), 2-Oxopomolic acid (3), 3-O-acetyl pomolic acid (4), fupenzic acid (5) and euscaphic acid (6). This is the first study in which these compounds have been isolated from the calyx of F. ananassa.
    CONCLUSIONS:
    Compared to a well-known inhibitor, α-arbutin, compounds 2-6 showed a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0547 mL 10.2733 mL 20.5465 mL 41.0931 mL 51.3663 mL
    5 mM 0.4109 mL 2.0547 mL 4.1093 mL 8.2186 mL 10.2733 mL
    10 mM 0.2055 mL 1.0273 mL 2.0547 mL 4.1093 mL 5.1366 mL
    50 mM 0.0411 mL 0.2055 mL 0.4109 mL 0.8219 mL 1.0273 mL
    100 mM 0.0205 mL 0.1027 mL 0.2055 mL 0.4109 mL 0.5137 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    2,3-O-异亚丙基刺梨酸; 2,3-O-Isopropylidenyl euscaphic acid CFN98095 220880-90-0 C33H52O5 = 528.8 5mg QQ客服:3257982914
    2-表委陵菜酸; 2-Epitormentic acid CFN99310 119725-19-8 C30H48O5 = 488.7 5mg QQ客服:2159513211
    2-氧代果树酸; 2-氧代坡模醇酸; 2-Oxopomolic acid CFN98920 54963-52-9 C30H46O5 = 486.7 5mg QQ客服:2159513211
    2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid; 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid CFN89112 176983-21-4 C30H46O5 = 486.69 5mg QQ客服:215959384
    覆盆子酸; Fupenzic acid CFN99311 119725-20-1 C30H44O5 = 484.7 5mg QQ客服:1413575084
    Negundonorin A; Negundonorin A CFN96848 1401618-51-6 C29H40O5 = 468.63 5mg QQ客服:3257982914
    1-beta-羟基蔷薇酸; 1beta-Hydroxyeuscaphic acid CFN92609 120211-98-5 C30H48O6 = 504.7 5mg QQ客服:3257982914
    1,2,3,19-四羟基-12-乌苏烯-28-酸; 1,2,3,19-Tetrahydroxy-12-ursen-28-oic acid CFN99233 113558-03-5 C30H48O6 = 504.7 5mg QQ客服:1413575084
    1-羟基-2-氧代果树酸; 1-Hydroxy-2-oxopomolic acid CFN98080 217466-37-0 C30H46O6 = 502.7 5mg QQ客服:2159513211
    3-O-顺式对香豆酰委陵菜酸; 3-O-cis-p-Coumaroyltormentic acid CFN92211 121072-40-0 C39H54O7 = 634.9 5mg QQ客服:1457312923

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