Glycinol
Glycinol
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| Glycinol |
CFN95122 |
69393-95-9 |
1mg |
QQ客服：215959384 |
| Glycinol |
CFN95122 |
69393-95-9 |
5mg |
QQ客服：215959384 |
| Glycinol |
CFN95122 |
69393-95-9 |
10mg |
QQ客服：215959384 |
| Glycinol |
CFN95122 |
69393-95-9 |
20mg |
QQ客服：215959384 |
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ChemFaces的产品在许多优秀和顶级科学期刊中被引用
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
Centralised Purchases Unit (CPU), B.I.T.S (India)
University of Bordeaux (France)
Macau University of Science and Technology (China)
Vin?a Institute of Nuclear Sciences (Serbia)
University of Virginia (USA)
Mendel University in Brno (Czech Republic)
Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
Leibniz Institute of Plant Biochemistry (Germany)
Celltrion Chemical Research Institute (Korea)
Harvard University (USA)
Universidade Federal de Santa Catarina (Brazil)
University of Malaya (Malaysia)
University of Brasilia (Brazil)
The University of Newcastle (Australia)
More...
国外学术期刊发表的引用ChemFaces产品的部分文献
| Description: |
Glycinol enhances osteogenic differentiation and attenuates the effects of age on mesenchymal stem cells, it could as a potential preventive or treatment for osteoporosis. Glycinol also has antidiuretic activity. |
| In vitro: |
| Regen Med. 2017 Jul;12(5):513-524. | | Glycinol enhances osteogenic differentiation and attenuates the effects of age on mesenchymal stem cells.[Pubmed: 28718749 ] | Phytoestrogens, such as glycinol, have recently gained significant attention as an alternative therapy for osteoporosis due to their structural similarity to estradiol and their bone-generating potential.
METHODS AND RESULTS:
The osteogenic effects of glycinol were investigated in human bone marrow mesenchymal stem cells (BMSCs) derived from older (>50 years old) and younger subjects (<25 years old).
BMSCs isolated from older donors demonstrated reduced osteogenesis. 17β-estradiol and glycinol exposure rescued the age-related reduction in osteogenic differentiation of BMSCs. These results correlated with the induction of osteogenic genes and estrogen receptor-α (ER-α) following glycinol treatment. ER antagonist studies further support that glycinol promotes osteogenesis through ER signaling.
CONCLUSIONS:
The results from these studies support investigating glycinol as a potential preventive or treatment for osteoporosis. |
|
| In vivo: |
| Eksp Klin Farmakol. 2010 Oct;73(10):21-4. | | [Influence of new neurohypophyseal hormone analogs on sodium and water reabsorption in rat kidney].[Pubmed: 21254509] | New analogs of some neurohypophyseal hormones (oxypressin, hydrin, glumitocin, vasotocin) have been synthesized.
METHODS AND RESULTS:
Experiments with injection of these peptides to rats showed that substitution of C-terminal glycinamide on beta-ethanolamine (glycinol) or ethylamine in 1-deamino-arginine vasotocin resulted in loss of natriuretic but not antidiuretic activity.
CONCLUSIONS:
Analogs of oxypressin and hydrin exhibited neither natriuretic activity nor ability to affect water reabsorption. Glumitocin analog induced renal sodium ion excretion and did not influence potassium ion excretion. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.6724 mL |
18.3621 mL |
36.7242 mL |
73.4484 mL |
91.8105 mL |
| 5 mM |
0.7345 mL |
3.6724 mL |
7.3448 mL |
14.6897 mL |
18.3621 mL |
| 10 mM |
0.3672 mL |
1.8362 mL |
3.6724 mL |
7.3448 mL |
9.1811 mL |
| 50 mM |
0.0734 mL |
0.3672 mL |
0.7345 mL |
1.469 mL |
1.8362 mL |
| 100 mM |
0.0367 mL |
0.1836 mL |
0.3672 mL |
0.7345 mL |
0.9181 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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