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  • Apterin

    Apterin

    Apterin
    产品编号 CFN95005
    CAS编号 53947-89-0
    分子式 = 分子量 C20H24O10 = 424.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Coumarins
    植物来源 The herbs of Peucedanum decursivum Maxim.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Apterin CFN95005 53947-89-0 1mg QQ客服:2159513211
    Apterin CFN95005 53947-89-0 5mg QQ客服:2159513211
    Apterin CFN95005 53947-89-0 10mg QQ客服:2159513211
    Apterin CFN95005 53947-89-0 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Chang Gung University (Taiwan)
  • University of Liège (Belgium)
  • University of the Basque Country (Spain)
  • University of Pretoria (South Africa)
  • University of Hertfordshire (United Kingdom)
  • Regional Crop Research Institute (Korea)
  • Utah State University (USA)
  • Cornell University (USA)
  • Chungnam National University (Korea)
  • Hamdard University (India)
  • Max-Planck-Insitut (Germany)
  • University of Oslo (Norway)
  • Pennsylvania State University (USA)
  • University of Cincinnati (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Scientific World Journal.2014, 2014:654193
  • Asian Journal of Chemistry2014, 26(22):7811-7816
  • Korean J. of Food Sci. and Tech2016, 172-177
  • Mediators Inflamm.2016, 2016:7216912
  • ARPN Journal of Eng.& Applied Sci.2016, 2199-2204
  • Int J Mol Med.2016, 37(2):501-8
  • J of the Korean Society of Food Science and Nutrition2016, 45(7):1017-1025
  • Jour. of Stored Pro & Postharvest Res.2016, 7(3):32-36
  • Sci Rep. 2017, 12953(7)
  • The Japan Society for Analytical Chemistry2017, 613-617
  • Nutrients.2018, 11(1):E17
  • J Cell Biochem.2018, 119(2):2231-2239
  • PLoS One.2018, 13(11):e0208055
  • Journal of Physiology & Pathology in Korean Medicine.2018, 32(2): 106-112
  • J Sep Sci.2018, 41(11):2488-2497
  • Biochem Biophys Res Commun.2018, 505(1):261-266
  • Biochem Biophys Res Commun.2018, 505(4):1148-1153
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1126-1127:121743
  • Int J Mol Sci.2019, 20(9):E2244
  • Life Sci.2019, 216:259-270
  • J Ethnopharmacol.2019, 228:132-141
  • Chem Biol Interact.2019, 298:1-7
  • Oncol Rep.2019, 41(4):2453-2463
  • ...
  • 生物活性
    Description: Apterin has anti-inflammatory activity in vitro, it shows significantly inhibitory activity on nitric oxide production in RAW264.7 cells.
    Targets: NO
    In vitro:
    J Agric Food Chem. 2003 Aug 27;51(18):5255-61.
    Antioxidant compounds from the leaves of Peucedanum japonicum thunb.[Pubmed: 12926867 ]
    Seventeen compounds were isolated from the n-butanol soluble fraction of the leaves of Peucedanum japonicum Thunb.
    METHODS AND RESULTS:
    On the basis of MS and various NMR spectroscopic techniques, the structures of the isolated compounds were determined as isoquercitrin (1), rutin (2), 3-O-caffeoylquinic acid (3), 4-O-caffeoylquinic acid (4), 5-O-caffeoylquinic acid (5), cnidioside A (6), praeroside II (7), praeroside III (8), apterin (9), esculin (10), (R)-peucedanol (11), (R)-peucedanol 7-O-beta-d-glucopyranoside (12), l-tryptophan (13), uracil (14), guanosine (15), uridine (16), and thymidine (17). All compounds except 11 and 12 were isolated for the first time from P. japonicum. Several isolated compounds were quantified by high-performance liquid chromatography analysis. In addition, all isolated compounds were examined for radical scavenging on 1,1-diphenyl-2-picrylhydrazyl radical and for inhibition of oxidation of liposome induced by 2,2'-azobis(2-amidinopropane)dihydrochloride.
    CONCLUSIONS:
    Compounds 2-5 were found to be the major potent constituents, which contribute to the antioxidant activity of P. japonicum leaves.
    In vivo:
    Chem Biodivers. 2017 Sep;14(9).
    A New Anti-Inflammatory Alkaloid from Roots of Heracleum dissectum.[Pubmed: 28556437 ]

    METHODS AND RESULTS:
    Using various chromatographic methods, a new piperidinone alkaloid, (3S)-3-{4-[(1E)-3-hydroxyprop-1-en-1-yl]-2-methoxyphenoxy}piperidin-2-one (1), together with 10 known compounds, bergapten (2), xanthotoxol (3), isopimpinellin (4), isobergapten (5), heratomol-6-O-β-d-glucopyranoside (6), scopoletin (7), apterin (8), 3-methoxy-4-β-d-glucopyranosyloxypropiophenone, (praeroside; 9), tachioside (10) and coniferin (11), were isolated from roots of Heracleum dissectum Ledeb. Their structures were elucidated on the basis of physicochemical properties and the detailed interpretation of various spectroscopic data.
    CONCLUSIONS:
    All the isolated compounds were screened for anti-inflammatory activity in vitro. As the results, compound 1 and 8 showed significantly inhibitory activity on nitric oxide production in RAW264.7 cells.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.3563 mL 11.7813 mL 23.5627 mL 47.1254 mL 58.9067 mL
    5 mM 0.4713 mL 2.3563 mL 4.7125 mL 9.4251 mL 11.7813 mL
    10 mM 0.2356 mL 1.1781 mL 2.3563 mL 4.7125 mL 5.8907 mL
    50 mM 0.0471 mL 0.2356 mL 0.4713 mL 0.9425 mL 1.1781 mL
    100 mM 0.0236 mL 0.1178 mL 0.2356 mL 0.4713 mL 0.5891 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    川白芷素; Angenomalin CFN91029 18199-64-9 C14H12O3 = 228.24 5mg QQ客服:1148253675
    山芹醇; Oroselol CFN95001 1891-25-4 C14H12O4 = 244.2 5mg QQ客服:215959384
    二氢山芹醇; Columbianetin CFN90185 3804-70-4 C14H14O4 = 246.26 20mg QQ客服:2159513211
    Angelidiol; Angelidiol CFN92989 156009-77-7 C14H14O5 = 262.26 5mg QQ客服:1413575084
    二氢山芹醇醋酸酯; Columbianetin acetate CFN90510 23180-65-6 C16H16O5 = 288.30 20mg QQ客服:1413575084
    二氢欧山芹醇当归酸酯; Columbianadin CFN99785 5058-13-9 C19H20O5 = 328.36 20mg QQ客服:1148253675
    二氢山芹醇 β-D-葡萄糖苷; Columbianetin beta-D-glucopyranoside CFN95038 55836-35-6 C20H24O9 = 408.4 5mg QQ客服:215959384
    Apterin; Apterin CFN95005 53947-89-0 C20H24O10 = 424.4 10mg QQ客服:2932563308
    3'-Angeloyloxy-4'-senecioyloxy-2',3'-dihydrooroselol; 3'-Angeloyloxy-4'-senecioyloxy-2',3'-dihydrooroselol CFN95123 1221686-60-7 C24H26O7 = 426.5 5mg QQ客服:1148253675

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