• 中药标准品生产商,产品定制服务
  • 2,5-二甲基-7-羟基色酮

    Altechromone A

    2,5-二甲基-7-羟基色酮
    产品编号 CFN89130
    CAS编号 38412-47-4
    分子式 = 分子量 C11H10O3 = 190.19
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The metabolites of Alternaria brassicicola ML-P08.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    2,5-二甲基-7-羟基色酮 CFN89130 38412-47-4 1mg QQ客服:1148253675
    2,5-二甲基-7-羟基色酮 CFN89130 38412-47-4 5mg QQ客服:1148253675
    2,5-二甲基-7-羟基色酮 CFN89130 38412-47-4 10mg QQ客服:1148253675
    2,5-二甲基-7-羟基色酮 CFN89130 38412-47-4 20mg QQ客服:1148253675
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • The Vancouver Prostate Centre (VPC) (Canada)
  • Universita' Degli Studi Di Cagliari (Italy)
  • Mendel University in Brno (Czech Republic)
  • University of Eastern Finland (Finland)
  • Helmholtz Zentrum München (Germany)
  • University of British Columbia (Canada)
  • University of Otago (New Zealand)
  • Indian Institute of Science (India)
  • University of Illinois (USA)
  • University of Amsterdam (Netherlands)
  • Cornell University (USA)
  • Sanford Burnham Medical Research Institute (USA)
  • Donald Danforth Plant Science Center (USA)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Mol Med Rep.2015, 12(5):7789-95
  • J. of Agricultural Science2015, 1916-9760
  • Tumour Biol.2015, 36(9):7027-34
  • J Pharm Biomed Anal.2016, 129:50-59
  • J Basic Clin Physiol Pharmacol.2016, 27(1):1-8
  • Int J Oncol.2016, 49(4):1497-504
  • Eur J Pharm Sci.2016, 94:33-45
  • Current Pharmaceutical Analysis2017, 13(5)
  • J Pharm Biomed Anal.2017, 140:274-280
  • University of Central Lancashire2017, 20472
  • Journal of Functional Foods2017, 30:30-38
  • Universidade Estadual Paulista2017, 42785
  • Sci Rep.2017, 7(1):3249
  • Front Aging Neurosci.2018, 10:269
  • PLoS One.2018, 13(4):e0195642
  • J of Engineering Science&Technology2018, 13(9):2820-2828
  • Br J Pharmacol.2018, 175(6):902-923
  • Arch Biochem Biophys.2018, 644:93-99
  • Molecules.2019, 24(23):E4303
  • Food Chem.2019, 290:286-294
  • J Enzyme Inhib Med Chem.2019, 34(1):134-143
  • Cell Physiol Biochem.2019, 52(6):1255-1266
  • Phytomedicine.2019, 55:229-237
  • ...
  • 生物活性
    Description: Altechromone A has antimicrobial activity, it is active against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively.
    Targets: Antifection
    In vitro:
    J Nat Prod. 2007 Jan;70(1):114-7.
    Cytotoxic benzo[j]fluoranthene metabolites from Hypoxylon truncatum IFB-18, an endophyte of Artemisia annua.[Pubmed: 17253861 ]

    METHODS AND RESULTS:
    Two new benzo[j]fluoranthene-based secondary metabolites named daldinone C (1) and daldinone D (2), along with two known metabolites, Altechromone A and (4S)-5,8-dihydroxy-4-methoxy-alpha-tetralone, were isolated from the CHCl3/MeOH (1:1) extract of a solid culture of the endophyte Hypoxylon truncatum IFB-18 harbored inside the symptomless stem tissue of Artemisia annua. The structures of the new compounds were elucidated by MS and 1D and 2D NMR spectra and by X-ray diffraction analysis. Their absolute configurations were determined unambiguously by a combination of their CD data and the established exciton chirality rule.
    CONCLUSIONS:
    Compounds 1 and 2 were substantially cytotoxic against SW1116 cells, with IC50 values of 49.5 and 41.0 microM, respectively, comparable to that (37.0 microM) of 5-fluorouracil. The biosynthetic pathway for 1 and 2 was postulated with the natural occurrence of benzo[j]fluoranthene analogues discussed in brief.
    World Journal of Microbiology & Biotechnology, 2009, 25(9):1677-1683.
    Bioactive metabolites from Alternaria brassicicola ML-P08, an endophytic fungus residing in Malus halliana[Reference: WebLink]

    METHODS AND RESULTS:
    A total of 48 strains were isolated from the normal tissues of Malus halliana and the EtOAc extracts of their cultures were subjected to primary antimicrobial screening against four test bacteria and three fungi. As a result, 22 strains exhibited antimicrobial activity against at least one test microbe. Among them, Alternaria brassicicola ML-P08 showing strong activity (MICs: 0.31–2.50 mg/ml) was selected for further investigation on its secondary metabolites. Bioassay-guided fractionation of the EtOAc extract of its liquid culture afforded seven compounds, which were identified as alternariol (1), alternariol 9-methyl ether (2), Altechromone A (3), herbarin A (4), cerevisterol (5), 3β,5α-dihydroxy-(22E,24R)-ergosta-7,22-dien-6-one (6) and 3β-hydroxy-(22E,24R)-ergosta-5,8,22-trien-7-one (7), respectively, by spectral means (MS, IR, 1H- and 13C-NMR).
    CONCLUSIONS:
    In vitro antimicrobial assay showed that compound 3 was substantially active against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 μg/ml, respectively. Compound 4 also showed pronounced antifungal activity against Trichophyton rubrum and C. albicans with MICs of both 15.6 μg/ml. In addition, compound 1 exhibited strong xanthine oxidase inhibitory activity with the IC50 of 15.5 μM, comparable to that of positive control, allopurinol (IC50: 10.7 μM).
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.2579 mL 26.2895 mL 52.579 mL 105.158 mL 131.4475 mL
    5 mM 1.0516 mL 5.2579 mL 10.5158 mL 21.0316 mL 26.2895 mL
    10 mM 0.5258 mL 2.6289 mL 5.2579 mL 10.5158 mL 13.1447 mL
    50 mM 0.1052 mL 0.5258 mL 1.0516 mL 2.1032 mL 2.6289 mL
    100 mM 0.0526 mL 0.2629 mL 0.5258 mL 1.0516 mL 1.3145 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Monnieriside A; Monnieriside A CFN92910 1401807-73-5 C16H18O10 = 370.31 5mg QQ客服:1413575084
    Cnidimol A ; Cnidimol A CFN96860 103629-80-7 C15H16O5 = 276.28 5mg QQ客服:215959384
    番樱桃素; Eugenin CFN90808 480-34-2 C11H10O4 = 206.2 10mg QQ客服:215959384
    8-Methyleugenitol; 8-Methyleugenitol CFN96198 41682-21-7 C12H12O4 = 220.2 5mg QQ客服:1148253675
    5,7-二羟基-2-(1-甲基乙基)-4H-1-苯并吡喃-4-酮; 5,7-Dihydroxy-2-isopropylchromone CFN97544 96552-59-9 C12H12O4 = 220.2 5mg QQ客服:3257982914
    8-Glucosyl-5,7-dihydroxy-2-(1-methylpropyl)chromone; 8-Glucosyl-5,7-dihydroxy-2-(1-methylpropyl)chromone CFN89218 188818-27-1 C19H24O9 = 396.39 5mg QQ客服:1148253675
    6-乙酰基-2,2-二甲基色满酮; 6-Acetyl-2,2-dimethylchroman-4-one CFN97171 68799-41-7 C13H14O3 = 218.3 5mg QQ客服:1413575084
    2,3-二氢-2,5-二甲基-4H-1-苯并吡喃-4-酮 ; 2,5-Dimethylchroman-4-one CFN96894 69687-87-2 C11H12O2 = 176.21 5mg QQ客服:1413575084
    2,5-二甲基-7-羟基色酮; Altechromone A CFN89130 38412-47-4 C11H10O3 = 190.19 5mg QQ客服:2932563308
    羟基甲基氧丙基苯并吡喃酮; Cassiachromone CFN98359 28955-30-8 C13H12O4 = 232.2 5mg QQ客服:215959384

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 215959384
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产