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  • bis[6-(5,6-dihydrochelerythrinyl)]amine

    bis[6-(5,6-dihydrochelerythrinyl)]amine

    bis[6-(5,6-dihydrochelerythrinyl)]amine
    产品编号 CFN91015
    CAS编号 165393-48-6
    分子式 = 分子量 C42H37N3O8 = 711.76
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 The herbs of Macleaya cordata
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    bis[6-(5,6-dihydrochelerythrinyl)]amine CFN91015 165393-48-6 1mg QQ客服:215959384
    bis[6-(5,6-dihydrochelerythrinyl)]amine CFN91015 165393-48-6 5mg QQ客服:215959384
    bis[6-(5,6-dihydrochelerythrinyl)]amine CFN91015 165393-48-6 10mg QQ客服:215959384
    bis[6-(5,6-dihydrochelerythrinyl)]amine CFN91015 165393-48-6 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universidad Industrial de Santander (Colombia)
  • The Vancouver Prostate Centre (VPC) (Canada)
  • Yale University (USA)
  • University of Wuerzburg (Germany)
  • Washington State University (USA)
  • Deutsches Krebsforschungszentrum (Germany)
  • Complutense University of Madrid (Spain)
  • University of Eastern Finland (Finland)
  • Mendel University in Brno (Czech Republic)
  • Imperial College London (United Kingdom)
  • Rio de Janeiro State University (Brazil)
  • University of Leipzig (Germany)
  • Universidad de Buenos Aires (Argentina)
  • Max Rubner-Institut (MRI) (Germany)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Institute of Food Science & Technology2021, 56(11).
  • J Food Sci Technol.2022, 59(1):212-219.
  • The Korea Journal of Herbology2019, 34(2):25-32
  • Horticulturae2021, 7(1),5.
  • Environ Toxicol.2023, tox.23999.
  • Int J Mol Med.2019, 43(6):2516-2522
  • Int J Mol Sci.2019, 20(23):E6071
  • Plants (Basel).2021, 10(7):1376.
  • Chemistry of plant raw materials2021, 1:pp 139-150
  • Food Analytical Methods2020, 1-10
  • J Agric Food Chem.2015, 63(44):9869-78
  • Plant Physiol Biochem.2023, 201:107795.
  • Postharvest Biol Tec2019, 149:18-26
  • Nat Commun.2023, 14(1):4540.
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1113:1-13
  • Applied Biological Chemistry2023, 66:85.
  • Curr Issues Mol Biol.2023, 45(3):2136-2156.
  • Malaysian Journal of Analytical Sciences2022, 26(2):360-369.
  • Pharmaceutics.2021, 13(7):1028.
  • Phytomedicine.2019, 58:152893
  • Appl. Sci.2021, 11(1),14.
  • QASCF2022, 14(4).
  • J. of Agricultural Science2015, 1916-9760
  • ...
  • 生物活性
    Description: BIS-[6-(5,6-dihydro-chelerythrinyl)] ether shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA).
    Targets: Antifection
    In vitro:
    Planta Med. 2011 Sep;77(13):1542-4.
    Chemical constituents, antimicrobial and antimalarial activities of Zanthoxylum monophyllum.[Pubmed: 21341176]

    METHODS AND RESULTS:
    From the leaves and bark of Zanthoxylum monophyllum, a new lignan, 3-methoxy-3',4'-methylenedioxylignan-4,8,9,9'-tetraol (1), has been isolated along with 22 known compounds (2- 23), fifteen of them reported for the first time from Z. monophyllum. Their chemical structures were elucidated using detailed spectroscopic studies and chemical analysis. All compounds were evaluated for antimicrobial and antiprotozoal activities.
    CONCLUSIONS:
    Alkaloids BIS-[6-(5,6-dihydro-chelerythrinyl)] ether (2) and 6-ethoxy-chelerythrine (4) exhibited strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA). Compound 4-methoxy-N-methyl-2-quinolone (9) exhibited significant activity against MRSA (IC50 value of 8.0 μM) while compound 5,8,4'-trihydroxy-3,7,3'-trimethoxyflavone (10) showed weak activity against Plasmodium falciparum.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.405 mL 7.0248 mL 14.0497 mL 28.0994 mL 35.1242 mL
    5 mM 0.281 mL 1.405 mL 2.8099 mL 5.6199 mL 7.0248 mL
    10 mM 0.1405 mL 0.7025 mL 1.405 mL 2.8099 mL 3.5124 mL
    50 mM 0.0281 mL 0.1405 mL 0.281 mL 0.562 mL 0.7025 mL
    100 mM 0.014 mL 0.0702 mL 0.1405 mL 0.281 mL 0.3512 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    乙酰紫堇灵; Acetylcorynoline CFN99749 18797-80-3 C23H23NO6 = 409.43 20mg QQ客服:1457312923
    白屈菜碱; Chelidonine CFN90319 476-32-4 C20H19NO5 = 353.37 20mg QQ客服:215959384
    二氢白屈菜红碱; Dihydrochelerythrine CFN90127 6880-91-7 C21H19NO4 = 349.38 20mg QQ客服:3257982914
    去甲白屈菜红碱; Norchelerythrine CFN92737 6900-99-8 C20H15NO4 = 333.3 5mg QQ客服:215959384
    氧基白屈菜季铵碱; Oxychelerythrine CFN97999 28342-33-8 C21H17NO5 = 363.4 5mg QQ客服:2056216494
    德卡林碱; Decarine CFN98909 54354-62-0 C19H13NO4 = 319.3 5mg QQ客服:1457312923
    氯化两面针碱; Nitidine chloride CFN98109 13063-04-2 C21H18ClNO4 = 383.83 20mg QQ客服:3257982914
    血根碱; Sanguinarine CFN98259 2447-54-3 C20H14NO4 = 332.3 20mg QQ客服:1413575084
    二氢血根碱; Dihydrosanguinarine CFN92810 3606-45-9 C20H15NO4 = 333.1 20mg QQ客服:1457312923
    6-Methoxydihydrosanguinarine; 6-Methoxydihydrosanguinarine CFN89299 72401-54-8 C21H17NO5 = 363.36 5mg QQ客服:215959384

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