| 产品编号 | CFN60007 | |
| CAS编号 | 1257044-40-8 | |
| 分子式 = 分子量 | C45H50ClN7O7S = 868.4 | |
| 产品纯度 | >=98% | |
| 物理属性 | Powder | |
| 化合物类型 | Alkaloids | |
| 植物来源 | ||
| ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 | ||
| 产品名称 | 产品编号 | CAS编号 | 包装 | QQ客服 |
| 维纳妥拉(ABT-199) | CFN60007 | 1257044-40-8 | 1mg | QQ客服:3004468087 |
| 维纳妥拉(ABT-199) | CFN60007 | 1257044-40-8 | 5mg | QQ客服:3004468087 |
| 维纳妥拉(ABT-199) | CFN60007 | 1257044-40-8 | 10mg | QQ客服:3004468087 |
| 维纳妥拉(ABT-199) | CFN60007 | 1257044-40-8 | 20mg | QQ客服:3004468087 |
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)| Description: | Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of <0.01 nM in cell-free assays, >4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1. Venetoclax is reported to induce cell growth suppression, apoptosis, cell cycle arrest, and autophagy in triple negative breast cancer MDA-MB-231 cells. |
| Targets: | Bcl-2 | Bcl-xL | Bcl-w | Autophagy |
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.1515 mL | 5.7577 mL | 11.5154 mL | 23.0309 mL | 28.7886 mL |
| 5 mM | 0.2303 mL | 1.1515 mL | 2.3031 mL | 4.6062 mL | 5.7577 mL |
| 10 mM | 0.1152 mL | 0.5758 mL | 1.1515 mL | 2.3031 mL | 2.8789 mL |
| 50 mM | 0.023 mL | 0.1152 mL | 0.2303 mL | 0.4606 mL | 0.5758 mL |
| 100 mM | 0.0115 mL | 0.0576 mL | 0.1152 mL | 0.2303 mL | 0.2879 mL |
| 产品名称 | 产品编号 | CAS编号 | 分子式 = 分子量 | 位单 | 联系QQ |
| 3,29-二苯甲酰基栝楼仁二醇; 3,29-O-Dibenzoyloxykarounidiol | CFN91175 | 389122-01-4 | C44H56O4 = 648.9 | 10mg | QQ客服:3004468091 |
| 樱桃甙; 洋李甙; Prunin | CFN98878 | 529-55-5 | C21H22O10 = 434.4 | 20mg | QQ客服:3004468091 |
| Odoratin-7-O-beta-D-glucopyranoside; Odoratin-7-O-beta-D-glucopyranoside | CFN91882 | 210413-47-1 | C23H24O11 = 476.43 | 5mg | QQ客服:3004468091 |
| 岩大戟内酯E; Jolkinolide E | CFN92872 | 54494-34-7 | C20H28O2 = 300.4 | 5mg | QQ客服:3004468091 |