蛇根亭碱

Serpentinine

	产品编号	CFN98499
	CAS编号	36519-42-3
	分子式 = 分子量	C₄₂H₄₄N₄O₅ = 684.8
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Alkaloids
	植物来源	The roots of Rauvolfia verticillata (Lour.) Baill.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
蛇根亭碱	CFN98499	36519-42-3	1mg	QQ客服：1457312923
蛇根亭碱	CFN98499	36519-42-3	5mg	QQ客服：1457312923
蛇根亭碱	CFN98499	36519-42-3	10mg	QQ客服：1457312923
蛇根亭碱	CFN98499	36519-42-3	20mg	QQ客服：1457312923

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Universite Libre de Bruxelles (Belgium)

Indian Institute of Science (India)

Stanford University (USA)

Heidelberg University (Germany)

China Medical University (Taiwan)

Mahatma Gandhi University (India)

Worcester Polytechnic Institute (USA)

VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)

Kyung Hee University (Korea)

Universidade de Franca (Brazil)

Martin Luther University of Halle-Wittenberg (Germany)

Washington State University (USA)

Chulalongkorn University (Thailand)

Subang Jaya Medical Centre (Malaysia)

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Description:

Serpentinine may have antihypertensive effect.

In vitro:

Current Hypertension Reviews,2010, 6(3):190-8.

Resurgence of Herbal Antihypertensives in Management of Hypertension.[Reference: WebLink]

Hypertension is one of the major cardiovascular problems and causes a number of vascular disorders. Until the 1940s majority of the diseases were treated by traditional drugs obtained from plants/herbs only. Even the first potent herbal antihypertensive was obtained from root of Rauwolfia serpentina, a famous Ayurvedic plant but soon the modern antihypertensives took the center-stage because of their precise, defined and fast action. However, due to their growing adverse effects, interest in the use of these drugs also gradually started waning. This has lead to the resurgence of marked awareness about traditional medicines and a considerable renewed global interest in the plant based drugs. Much emphasis is now being given to validate the extract/fraction as well as single molecules obtained from plant resources based on their traditional claims.
METHODS AND RESULTS:
In this review, we have laid emphasis on the mechanistic aspect of antihypertensive effect of some medicinal plants and their therapeutic use. We have further tried to shed light on the attempts being made for the validation and documentation of traditional plants and herbs for their future development as potential therapy in hypertension. What's already known? • The herbal medications had been used since long to treat various cardiovascular disorders including high blood pressure before the arrival of modern therapy. • Global interest has now been renewed in herbal medicines but need authentication and validation in support of their therapeutic value. What this article may add? • This review emphasizes the mechanistic aspect of herbal medicines, their therapeutic values in clinical situation as well as present measures and recent approaches to validate and document their antihypertensive efficacies.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
Rauvotetraphylline E; Rauvotetraphylline E	CFN96746	1422506-53-3	C₂₀H₁₉N₂O₃ = 335.4	5mg	QQ客服：215959384
鸭脚木碱; Alstonine	CFN97709	642-18-2	C₂₁H₂₁N₂O₃ = 349.4	5mg	QQ客服：215959384
阿枯米精; Akuammigine	CFN97710	642-17-1	C₂₁H₂₄N₂O₃ = 352.43	5mg	QQ客服：215959384
Serpentinic acid; Serpentinic acid	CFN97721	605-14-1	C₂₀H₁₉N₂O₃ = 335.38	5mg	QQ客服：2159513211
19-表阿马碱; Mayumbine	CFN98283	25532-45-0	C₂₁H₂₄N₂O₃ = 352.4	5mg	QQ客服：2159513211
蛇根亭碱; Serpentinine	CFN98499	36519-42-3	C₄₂H₄₄N₄O₅ = 684.8	5mg	QQ客服：1457312923
(4R)-阿马碱N-氧化物; 4,R-ajmalicine N-oxide	CFN98652	41590-29-8	C₂₁H₂₄N₂O₄ = 368.4	5mg	QQ客服：215959384
阿立新碱; Aricine	CFN98760	482-91-7	C₂₂H₂₆N₂O₄ = 382.5	5mg	QQ客服：1457312923
萝巴新；阿吗碱; Ajmalicine	CFN98761	483-04-5	C₂₁H₂₄N₂O₃ = 352.4	5mg	QQ客服：3257982914
蛇纹石素; Serpentine	CFN99867	18786-24-8	C₂₁H₂₁N₂O₃ = 349.4	5mg	QQ客服：2159513211

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.4603 mL	7.3014 mL	14.6028 mL	29.2056 mL	36.507 mL
5 mM	0.2921 mL	1.4603 mL	2.9206 mL	5.8411 mL	7.3014 mL
10 mM	0.146 mL	0.7301 mL	1.4603 mL	2.9206 mL	3.6507 mL
50 mM	0.0292 mL	0.146 mL	0.2921 mL	0.5841 mL	0.7301 mL
100 mM	0.0146 mL	0.073 mL	0.146 mL	0.2921 mL	0.3651 mL