脯氨酸
Proline
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| 脯氨酸 |
CFN99612 |
147-85-3 |
10mg |
QQ客服：2056216494 |
| 脯氨酸 |
CFN99612 |
147-85-3 |
20mg |
QQ客服：2056216494 |
| 脯氨酸 |
CFN99612 |
147-85-3 |
50mg |
QQ客服：2056216494 |
| 脯氨酸 |
CFN99612 |
147-85-3 |
100mg |
QQ客服：2056216494 |
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ChemFaces的产品在许多优秀和顶级科学期刊中被引用
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
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Universidade de Franca (Brazil)
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Regional Crop Research Institute (Korea)
More...
国外学术期刊发表的引用ChemFaces产品的部分文献
| Description: |
L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.Proline accumulates in many plant species in response to environmental stress, it can act as a signaling molecule to modulate mitochondrial functions, influence cell proliferation or cell death and trigger specific gene expression, which can be essential for plant recovery from stress, the engineering of proline metabolism could lead to new opportunities to improve plant tolerance of environmental stresses. |
| Targets: |
p38MAPK | HIF |
| In vitro: |
| Science. 2001 Apr 20;292(5516):464-8. | | HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.[Pubmed: 11292862 ] | | HIF (hypoxia-inducible factor) is a transcription factor that plays a pivotal role in cellular adaptation to changes in oxygen availability. In the presence of oxygen, HIF is targeted for destruction by an E3 ubiquitin ligase containing the von Hippel-Lindau tumor suppressor protein (pVHL). We found that human pVHL binds to a short HIF-derived peptide when a conserved proline residue at the core of this peptide is hydroxylated. Because proline hydroxylation requires molecular oxygen and Fe(2+), this protein modification may play a key role in mammalian oxygen sensing. |
|
| In vivo: |
| Trends Plant Sci. 2010 Feb;15(2):89-97. | | Proline: a multifunctional amino acid.[Pubmed: 20036181 ] | | Proline accumulates in many plant species in response to environmental stress. Although much is now known about proline metabolism, some aspects of its biological functions are still unclear. Here, we discuss the compartmentalization of proline biosynthesis, accumulation and degradation in the cytosol, chloroplast and mitochondria. We also describe the role of proline in cellular homeostasis, including redox balance and energy status. Proline can act as a signaling molecule to modulate mitochondrial functions, influence cell proliferation or cell death and trigger specific gene expression, which can be essential for plant recovery from stress. Although the regulation and function of proline accumulation are not yet completely understood, the engineering of proline metabolism could lead to new opportunities to improve plant tolerance of environmental stresses. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
8.6881 mL |
43.4405 mL |
86.881 mL |
173.7619 mL |
217.2024 mL |
| 5 mM |
1.7376 mL |
8.6881 mL |
17.3762 mL |
34.7524 mL |
43.4405 mL |
| 10 mM |
0.8688 mL |
4.344 mL |
8.6881 mL |
17.3762 mL |
21.7202 mL |
| 50 mM |
0.1738 mL |
0.8688 mL |
1.7376 mL |
3.4752 mL |
4.344 mL |
| 100 mM |
0.0869 mL |
0.4344 mL |
0.8688 mL |
1.7376 mL |
2.172 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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