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  • N-反式咖啡酰酪胺

    N-trans-caffeoyltyramine

    N-反式咖啡酰酪胺
    产品编号 CFN95265
    CAS编号 103188-48-3
    分子式 = 分子量 C17H17NO4 = 299.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 The roots of Litsea hypophaea
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    N-反式咖啡酰酪胺 CFN95265 103188-48-3 1mg QQ客服:2932563308
    N-反式咖啡酰酪胺 CFN95265 103188-48-3 5mg QQ客服:2932563308
    N-反式咖啡酰酪胺 CFN95265 103188-48-3 10mg QQ客服:2932563308
    N-反式咖啡酰酪胺 CFN95265 103188-48-3 20mg QQ客服:2932563308
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Jour. of Stored Pro & Postharvest Res.2016, 7(3):32-36
  • Biochem Biophys Res Commun.2020, 522(1):40-46
  • Biosci Biotechnol Biochem.2020, 84(3):621-632
  • Agriculture2022, 12(2),227.
  • Research on Crops.2017, 18(3):569
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  • Food Chem.2022, 373(Pt B):131364.
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  • Pharmaceuticals.2022, 15(4), 402.
  • Molecules.2018, 23(11):E2837
  • Foods.2021, 10(12):2929.
  • Nutr Res Pract.2020, 14(5):478-489.
  • J Hematol Oncol.2018, 11(1):112
  • Korean Herb. Med. Inf. 2016, 4(1):35-42
  • Phytomedicine.2022, 100:154036.
  • Chem Res Toxicol. 2022, acs.chemrestox.2c00049.
  • Mediators Inflamm. 2016, 2016:6189590
  • J Appl Biol Chem2021, 64(3):245-251.
  • J of Physics Conference Series2019, 1349(1)
  • Int J Mol Sci.2022, 23(13):7115.
  • Nutrients.2019, 11(4):E936
  • ...
  • 生物活性
    Description: N-trans-caffeoyltyramine is a novel and potent modulator of inflammatory responses.
    In vitro:
    International Journal of Molecular Medicine, 2015,3:1042-1048.
    N‑trans‑ρ‑caffeoyl tyramine isolated from Tribulus terrestris exerts anti‑inflammatory effects in lipopolysaccharide‑stimulated RAW 264.7 cells.[Reference: WebLink]
    Inflammation is induced by the expression of cyclooxygenase‑2 (COX‑2), which is an important mediator of chronic inflammatory diseases, such as rheumatoid arthritis, asthma and inflammatory bowel disease. Tribulus terrestris (T. terrestris) is known to have a beneficial effect on inflammatory diseases.
    METHODS AND RESULTS:
    In this study, we investigated the effects of N‑trans‑ρ‑caffeoyltyramine (N-trans-caffeoyltyramine,CT) isolated from T. terrestris on the production of nitric oxide (NO), and the expression of pro‑inflammatory cytokines and COX‑2 in lipopolysaccharide (LPS)‑stimulated RAW 264.7 cells. We also aimed to elucidate the molecular mechanisms involved. We found that the ethanolic extract of T. terrestris (EETT) and CT inhibited the production of NO, tumor necrosis factor‑α (TNF‑α), interleukin (IL)‑6 and IL‑10 in the LPS‑stimulated RAW 264.7 cells in a dose‑dependent manner. They were determined by reverse transcription-polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA). In addition, CT markedly suppressed the expression of COX‑2 and the production of prostaglandin E2 (PGE2) in response to LPS stimulation. Furthermore, CT markedly decreased p‑c‑Jun N‑terminal kinase (p‑JNK) protein expression in LPS‑stimulated RAW 264.7 cells. COX-2 and p-JNK were measured by western blot analysis.
    CONCLUSIONS:
    Taken together, these findings indicate that CT isolated from T. terrestris is a novel and potent modulator of inflammatory responses. Thus, it may prove benefiical to further evaluate CT as a possible treatment for chronic inflammatory diseases.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.3411 mL 16.7056 mL 33.4113 mL 66.8226 mL 83.5282 mL
    5 mM 0.6682 mL 3.3411 mL 6.6823 mL 13.3645 mL 16.7056 mL
    10 mM 0.3341 mL 1.6706 mL 3.3411 mL 6.6823 mL 8.3528 mL
    50 mM 0.0668 mL 0.3341 mL 0.6682 mL 1.3365 mL 1.6706 mL
    100 mM 0.0334 mL 0.1671 mL 0.3341 mL 0.6682 mL 0.8353 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    3,4-二羟基肉桂酰胺; 3,4-Dihydroxycinnamamide CFN99316 1202-41-1 C9H9NO3 = 179.2 5mg QQ客服:1413575084
    3-[3,4-双(乙酰氧基)苯基]-2-丙烯酰胺; 3,4-Diacetoxycinnamamide CFN99390 129488-34-2 C13H13NO5 = 263.3 5mg QQ客服:1148253675
    阿魏酸酰胺; Ferulamide CFN97041 61012-31-5 C10H11NO3 = 193.2 5mg QQ客服:1148253675
    印枳碱; Aegeline CFN91133 456-12-2 C18H19NO3 = 297.4 20mg QQ客服:2159513211
    N-咖啡酰O-甲基酪胺; N-Caffeoyl O-methyltyramine CFN70295 189307-47-9 C18H19NO4 = 313.4 5mg QQ客服:2159513211
    N-反式咖啡酰真蛸胺; N-trans-caffeoyloctopamine CFN95264 1378868-10-0 C17H17NO5 = 315.3 5mg QQ客服:1148253675
    N-反式咖啡酰酪胺; N-trans-caffeoyltyramine CFN95265 103188-48-3 C17H17NO4 = 299.3 5mg QQ客服:1413575084
    N-反式阿魏酰酪胺; N-trans-Feruloyltyramine CFN97135 66648-43-9 C18H19NO4 = 313.4 10mg QQ客服:2159513211
    N-反式-阿魏酰-3-甲氧基酪胺; N-trans-Feruloyl-3-methoxytyramine CFN97268 78510-19-7 C19H21NO5 = 343.4 5mg QQ客服:1413575084
    芥子酰酪胺; N-trans-Sinapoyltyramine CFN91137 200125-11-7 C19H21NO5 = 343.4 10mg QQ客服:2932563308

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