3'-二甲基烯丙基染料木黄酮
Isowighteone
|
|
产品编号 |
CFN97166 |
| CAS编号 |
68436-47-5 |
| 分子式 = 分子量 |
C20H18O5 = 338.4 |
| 产品纯度 |
>=98% |
| 物理属性 |
Yellow powder |
| 化合物类型 |
Flavonoids |
| 植物来源 |
The roots of Sophora flavescens. |
| ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 |
|
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| 3'-二甲基烯丙基染料木黄酮 |
CFN97166 |
68436-47-5 |
1mg |
QQ客服：2056216494 |
| 3'-二甲基烯丙基染料木黄酮 |
CFN97166 |
68436-47-5 |
5mg |
QQ客服：2056216494 |
| 3'-二甲基烯丙基染料木黄酮 |
CFN97166 |
68436-47-5 |
10mg |
QQ客服：2056216494 |
| 3'-二甲基烯丙基染料木黄酮 |
CFN97166 |
68436-47-5 |
20mg |
QQ客服：2056216494 |
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Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
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Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
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国外学术期刊发表的引用ChemFaces产品的部分文献
| Description: |
Isowighteone, a compound that is not naturally produced in this species, accumulated by medicago truncatula hairy roots expressing LaPT1, indicates a strategy for metabolic engineering of novel antimicrobial compounds in legumes; it may have antimicrobial activity against fungal pathogens of plants. |
| Targets: |
Antifection |
| In vitro: |
| Plant Physiol. 2012 May;159(1):70-80. | | Characterization of an isoflavonoid-specific prenyltransferase from Lupinus albus.[Pubmed: 22430842] | Prenylated flavonoids and isoflavonoids possess antimicrobial activity against fungal pathogens of plants. However, only a few plant flavonoid and isoflavonoid prenyltransferase genes have been identified to date.
METHODS AND RESULTS:
In this study, an isoflavonoid prenyltransferase gene, designated as LaPT1, was identified from white lupin (Lupinus albus). The deduced protein sequence of LaPT1 shared high homologies with known flavonoid and isoflavonoid prenyltransferases. The LaPT1 gene was mainly expressed in roots, a major site for constitutive accumulation of prenylated isoflavones in white lupin. LaPT1 is predicted to be a membrane-bound protein with nine transmembrane regions and conserved functional domains similar to other flavonoid and isoflavonoid prenyltransferases; it has a predicted chloroplast transit peptide and is plastid localized. A microsomal fraction containing recombinant LaPT1 prenylated the isoflavone genistein at the B-ring 3' position to produce Isowighteone. The enzyme is also active with 2'-hydroxygenistein but has no activity with other flavonoid substrates. The apparent K(m) of recombinant LaPT1 for the dimethylallyl diphosphate prenyl donor is in a similar range to that of other flavonoid prenyltransferases, but the apparent catalytic efficiency with genistein is considerably higher. Removal of the transit peptide increased the apparent overall activity but also increased the K(m).
CONCLUSIONS:
Medicago truncatula hairy roots expressing LaPT1 accumulated Isowighteone, a compound that is not naturally produced in this species, indicating a strategy for metabolic engineering of novel antimicrobial compounds in legumes. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.9551 mL |
14.7754 mL |
29.5508 mL |
59.1017 mL |
73.8771 mL |
| 5 mM |
0.591 mL |
2.9551 mL |
5.9102 mL |
11.8203 mL |
14.7754 mL |
| 10 mM |
0.2955 mL |
1.4775 mL |
2.9551 mL |
5.9102 mL |
7.3877 mL |
| 50 mM |
0.0591 mL |
0.2955 mL |
0.591 mL |
1.182 mL |
1.4775 mL |
| 100 mM |
0.0296 mL |
0.1478 mL |
0.2955 mL |
0.591 mL |
0.7388 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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