灵芝酸F

Ganoderic acid F

	产品编号	CFN92055
	CAS编号	98665-15-7
	分子式 = 分子量	C₃₂H₄₂O₉ = 570.7
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Triterpenoids
	植物来源	The fruiting bodys of Ganoderma lucidum
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
灵芝酸F	CFN92055	98665-15-7	10mg	QQ客服：1457312923
灵芝酸F	CFN92055	98665-15-7	20mg	QQ客服：1457312923
灵芝酸F	CFN92055	98665-15-7	50mg	QQ客服：1457312923
灵芝酸F	CFN92055	98665-15-7	100mg	QQ客服：1457312923

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Amity University (India)

The Institute of Cancer Research (United Kingdom)

Donald Danforth Plant Science Center (USA)

University of Mysore (India)

Monash University Sunway Campus (Malaysia)

Charles Sturt University (Denmark)

Universiti Malaysia Pahang (Malaysia)

University of Otago (New Zealand)

Weizmann Institute of Science (Israel)

Vin?a Institute of Nuclear Sciences (Serbia)

University of Padjajaran (Indonesia)

National Cancer Institute (USA)

University of Amsterdam (Netherlands)

Institute of Tropical Disease Universitas Airlangga (Indonesia)

More...

Description:

Ganoderic acid F has anti-hepatitis B, anti-inflammatory, and anti-tumor-promoting activities.

Targets:

HBV | Immunology & Inflammation related

In vivo:

Evid Based Complement Alternat Med. 2012;2012:780892.

Pharmacokinetics of ganoderic acids a and f after oral administration of ling zhi preparation in healthy male volunteers.[Pubmed: 22577465]

The objectives of this paper were to evaluate the pharmacokinetics of ganoderic acid A and Ganoderic acid F after a single oral dose of the water extract of MG2-strain Ling Zhi (MG2FB-WE) and to assess the influence of food on the pharmacokinetics in 12 healthy male volunteers.
METHODS AND RESULTS:
This study was a single-dose, open-label, randomized, two-phase crossover study with at least 2 wk washout period. Each subject was randomly assigned to receive a single oral dose of 3,000 mg of MG2FB-WE in granular formulation dissolved in 200 mL of warm water, either under a fasting condition, or immediately after a standard breakfast (fed condition). Blood samples were collected immediately before and at specific time points until 8 h after MG2FB-WE administration. Plasma ganoderic acid A and Ganoderic acid F concentrations were determined by using liquid chromatography-mass spectrometry (LC-MS) technique.
CONCLUSIONS:
In conclusion, the pharmacokinetic profile of both ganoderic acids under a fasting condition was characterized by rapid absorption from the gastrointestinal tract (T(max) at approximately 30 min) and a short elimination half-life (<40 min). Food significantly decreased C(max) and delayed T(max), but did not affect the extent of ganoderic acid A absorption. However, concomitant food intake markedly impeded both rate and extent of Ganoderic acid F absorption.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
灵芝酸H; Ganoderic acid H	CFN92056	98665-19-1	C₃₂H₄₄O₉ = 572.7	10mg	QQ客服：2159513211
灵芝酸H甲酯; Methyl ganoderate H	CFN92291	98665-11-3	C₃₃H₄₆O₉ = 586.7	5mg	QQ客服：1457312923
Ganoweberianic acid E; Ganoweberianic acid E	CFN95504	1309931-90-5	C₃₂H₄₄O₉ = 572.7	5mg	QQ客服：3257982914
12beta-Acetoxy-3beta-hydroxy-7,11,15,23-tetraoxo-lanost-8,20-diene-26-oic acid; 12beta-Acetoxy-3beta-hydroxy-7,11,15,23-tetraoxo-lanost-8,20-diene-26-oic acid	CFN95468	1085338-75-5	C₃₂H₄₂O₉ = 570.7	5mg	QQ客服：2056216494
12beta-Acetoxy-3,7,11,15,23-pentaoxo-lanost-8,20-dien-26-oic acid; 12beta-Acetoxy-3,7,11,15,23-pentaoxo-lanost-8,20-dien-26-oic acid	CFN95505	1309931-91-6	C₃₂H₄₀O₉ = 568.7	5mg	QQ客服：2159513211
去乙酰基灵芝酸F; Deacetyl ganoderic acid F	CFN90746	100665-44-9	C₃₀H₄₀O₈ = 528.6	5mg	QQ客服：1413575084
灵芝酸F; Ganoderic acid F	CFN92055	98665-15-7	C₃₂H₄₂O₉ = 570.7	20mg	QQ客服：215959384
灵芝酸F甲酯; Methyl ganoderate F	CFN95584	98665-08-8	C₃₃H₄₄O₉ = 584.7	5mg	QQ客服：1413575084
12beta-Acetoxy-7beta-hydroxy-3,11,15,23-tetraoxo-5alpha-lanosta-8,20-dien-26-oic acid; 12beta-Acetoxy-7beta-hydroxy-3,11,15,23-tetraoxo-5alpha-lanosta-8,20-dien-26-oic acid	CFN95515	1245946-62-6	C₃₂H₄₂O₉ = 570.7	5mg	QQ客服：2159513211
灵芝烯酸K; Ganoderenic acid K	CFN95469	942950-94-9	C₃₂H₄₄O₉ = 572.7	10mg	QQ客服：1457312923

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.7522 mL	8.7612 mL	17.5223 mL	35.0447 mL	43.8059 mL
5 mM	0.3504 mL	1.7522 mL	3.5045 mL	7.0089 mL	8.7612 mL
10 mM	0.1752 mL	0.8761 mL	1.7522 mL	3.5045 mL	4.3806 mL
50 mM	0.035 mL	0.1752 mL	0.3504 mL	0.7009 mL	0.8761 mL
100 mM	0.0175 mL	0.0876 mL	0.1752 mL	0.3504 mL	0.4381 mL