Eriosemation

	产品编号	CFN92835
	CAS编号	162616-72-0
	分子式 = 分子量	C₁₉H₂₂O₄ = 314.4
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Flavonoids
	植物来源	The roots of Lupinus luteus
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

提供自定义包装

产品名称	产品编号	CAS编号	包装	QQ客服
Eriosemation	CFN92835	162616-72-0	1mg	QQ客服：2056216494
Eriosemation	CFN92835	162616-72-0	5mg	QQ客服：2056216494
Eriosemation	CFN92835	162616-72-0	10mg	QQ客服：2056216494
Eriosemation	CFN92835	162616-72-0	20mg	QQ客服：2056216494

存储与注意事项

1. 在您收到产品后请检查产品。如无问题，请将产品存入冰霜并且样品瓶保持密封，产品可以存放长达24个月（2-8摄氏度）。

2. 只要有可能，产品溶解后，您应该在同一天应用于您的实验。但是，如果您需要提前做预实验，或者需要全部溶解，我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。通常，这些可用于长达两周。使用前，打开样品瓶前，我们建议您将产品平衡至室温至少1小时。

3. 需要更多关于溶解度，使用和处理的建议？请发送电子邮件至：service@chemfaces.com

订购流程

1. 在线订购

请联系我们QQ客服

2. 电话订购

请拨打电话：
027-84237683 或 027-84237783

3. 邮件或传真订购

发送电子邮件到: manager@chemfaces.com 或
发送传真到：027-84254680

提供订购信息

为了方便客户的订购，请需要订购ChemFaces产品的客户，在下单的时候请提供下列信息，以供我们快速为您建立发货信息。

1. 产品编号（CAS No.或产品名称）

2. 发货地址

3. 联系方法 (联系人，电话）

4. 开票抬头 (如果需要发票的客户）

5. 发票地址（发货地址与发票地址不同）

发货时间

1. 付款方式为100%预付款客户，我们将在确认收到货款后当天或1-3个工作日发货。

2. 付款方式为月结的客户，我们承诺在收到订单后当天或1-3个工作日内发货。

3. 如果客户所需要的产品，需要重新生产，我们有权告知客户，交货时间需要延期。

ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

University of Mysore (India)

Macau University of Science and Technology (China)

VIT University (India)

National Cancer Center Research Institute (Japan)

Almansora University (Egypt)

Chulalongkorn University (Thailand)

CSIRO - Agriculture Flagship (Australia)

Amity University (India)

University of Amsterdam (Netherlands)

Max Rubner-Institut (MRI) (Germany)

Kazusa DNA Research Institute (Japan)

Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)

University of Zurich (Switzerland)

Centrum Menselijke Erfelijkheid (Belgium)

More...

Description:

Eriosemation significant androgen receptor (AR) inhibition activity, suggests that it could be a promising candidate for further evaluation for prostate cancer prevention or management.

Targets:

Androgen Receptor

In vitro:

Sci Rep. 2017 May 16;7(1):1955.

Structure Based docking studies towards exploring potential anti-androgen activity of selected phytochemicals against Prostate Cancer.[Pubmed: 28512306 ]

Prostate cancer (PCa) is the second most common malignancy amongst men worldwide. Under PCa maintenance therapy drugs acting as antagonists/partial agonists of hormone receptors against the prostate tissue are used in clinical practices. Prominent drugs being Cyproterone acetate, Flutamide, Bicalutamide, they not only cause acute and long-term toxicity, but also develops drug resistance among patients.Our focus has been on phytochemicals which do not exhibit any cytotoxicity and have significant androgen receptor (AR) inhibition activity.
METHODS AND RESULTS:
As Protein- Ligand interactions play a key role in structure based drug design, so by using molecular docking, we screened 803 phytochemicals and investigated their binding affinity against AR. The three dimensional (3D) structure of AR was retrieved from Protein Data Bank, and docked with 3D Pubchem structures of 803 phytochemicals using Argus Lab. Molecular docking and drug likeness studies were made using ADMET properties while Lipinski's rule of five was performed for the phytochemicals to evaluate their anti-prostate cancer activity.
CONCLUSIONS:
The results showed that Isobavachin exhibited best binding affinity of -13.73 kcal/mol with AR followed by Glabranin, Anthocyanin and Eriosemation. Our studies therefore reveal that these four phytochemicals could be promising candidates for further evaluation for PCa prevention or management.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
白屈菜酸; Chelidonic acid	CFN94111	99-32-1	C₇H₄O₆ = 184.10	20mg	QQ客服：2159513211
去甲氧基茵陈色原酮; Demethoxycapillarisin	CFN97716	61854-36-2	C₁₅H₁₀O₆ = 286.24	5mg	QQ客服：3257982914
7-O-去甲氧基茵陈色原酮; Demethoxy-7-O-methylcapillarisin	CFN96209	61854-37-3	C₁₆H₁₂O₆ = 300.3	5mg	QQ客服：1457312923
茵陈色原酮; Capillarisin	CFN90317	56365-38-9	C₁₆H₁₂O₇ = 316.26	5mg	QQ客服：3257982914
Epimedonin B; Epimedonin B	CFN92907	1616061-69-8	C₂₀H₁₆O₆ = 352.34	5mg	QQ客服：1413575084
5,7-二羟基色原酮; 5,7-Dihydroxychromone	CFN97761	31721-94-5	C₉H₆O₄ = 178.14	20mg	QQ客服：3257982914
5,7-二羟基色原酮 7-芸香糖苷; 5,7-Dihydroxychromone 7-rutinoside	CFN92369	52538-46-2	C₂₁H₂₆O₁₃ = 486.4	5mg	QQ客服：2159513211
3,5,7-三羟基色原酮; 3,5,7-Trihydroxychromone	CFN89191	31721-95-6	C₉H₆O₅ = 194.14	5mg	QQ客服：215959384
Eriosematin A; Eriosematin A	CFN92552	175448-02-9	C₁₄H₁₄O₄ = 246.3	5mg	QQ客服：215959384
Eriosemation; Eriosemation	CFN92835	162616-72-0	C₁₉H₂₂O₄ = 314.4	5mg	QQ客服：2159513211

信息支持

公司简介
订购流程
付款方式
退换货政策

ChemFaces提供的产品仅用于科学研究使用，不用于诊断或治疗程序。

联系方式

电机：027-84237783
传真：027-84254680
在线QQ: 1413575084
E-Mail：manager@chemfaces.com

湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房

ChemFaces为科学家，科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产。

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.1807 mL	15.9033 mL	31.8066 mL	63.6132 mL	79.5165 mL
5 mM	0.6361 mL	3.1807 mL	6.3613 mL	12.7226 mL	15.9033 mL
10 mM	0.3181 mL	1.5903 mL	3.1807 mL	6.3613 mL	7.9517 mL
50 mM	0.0636 mL	0.3181 mL	0.6361 mL	1.2723 mL	1.5903 mL
100 mM	0.0318 mL	0.159 mL	0.3181 mL	0.6361 mL	0.7952 mL