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  • 乙酸二聚松柏酯

    Dimeric coniferyl acetate

    乙酸二聚松柏酯
    产品编号 CFN99853
    CAS编号 184046-40-0
    分子式 = 分子量 C24H26O8 = 442.5
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Lignans
    植物来源 The herbs of Jatropha integerrima
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    乙酸二聚松柏酯 CFN99853 184046-40-0 1mg QQ客服:3257982914
    乙酸二聚松柏酯 CFN99853 184046-40-0 5mg QQ客服:3257982914
    乙酸二聚松柏酯 CFN99853 184046-40-0 10mg QQ客服:3257982914
    乙酸二聚松柏酯 CFN99853 184046-40-0 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Mysore (India)
  • Universidade da Beira Interior (Germany)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • University of Liège (Belgium)
  • Agricultural Research Organization (ARO) (Israel)
  • Universidade Federal de Pernambuco (UFPE) (Brazil)
  • Universit?t Basel (Switzerland)
  • Mendel University in Brno (Czech Republic)
  • Universidade Católica Portuguesa (Portugal)
  • University of Eastern Finland (Finland)
  • University of Vigo (Spain)
  • Utrecht University (Netherlands)
  • Universidade Federal de Goias (UFG) (Brazil)
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Front Plant Sci.2022, 13:982771.
  • J Biol Chem.2014, 289(3):1723-31
  • Pharmacognosy Magazine2018, 14(56):418-424
  • Korean Herb. Med. Inf.2021, 9(2):231-239.
  • J Nat Med.2021, doi: 10.1007.
  • Sci Rep.2019, 9(1):6429
  • Antioxidants.2022, 11(3):592.
  • Iranian J. Pharm. Res.2021, 20(4):59-70
  • Evidence-based Compl.&Alternative Med.2023, 5417813
  • Biochem Biophys Res Commun.2021, 534:802-807.
  • Cancers (Basel).2023, 15(1):37.
  • BMC Pharmacol Toxicol.2018, 19(1):5
  • Int J Pharm.2022, 618:121636.
  • Pharmacogn J.2022, 14(2):350-357
  • Int J Oncol.2016, 49(4):1497-504
  • Front Pharmacol.2018, 9:756
  • Antioxidants (Basel).2021, 10(10):1620.
  • J Ethnopharmacol.2016, 192:370-381
  • Molecules.2019, 24(11):E2044
  • J Sci Food Agric.2017, 97(5):1656-1662
  • Sci Rep.2021, 11(1):21038.
  • Molecules.2020, 25(21):5087.
  • JPC-Journal of Planar Chromatography2023, 36:179-190
  • ...
  • 生物活性
    Description: Dimeric coniferyl acetate has anti-inflammary activity, it shows strong NO inhibition with IC50 values of 27.1 uM in lipopolysacchalide (LPS)-activated murine macrophage-like J774.1 cells. It exhibits significant inhibitory effects on the nitric oxide production in lipopolysaccharide activated C57BL6/J mouse macrophages.
    Targets: NO
    In vitro:
    Journal of Traditional Medicines, 2003, 20: 22-9.
    Inhibitors of nitric oxide (NO) production in murine macrophage-like J774.1 cells from Brazilian propolis[Reference: WebLink]

    METHODS AND RESULTS:
    Water and MeOH extracts of Brazilian propolis showed dose-dependent inhibition toward nitric oxide (NO) production in lipopolysacchalide (LPS)-activated murine macrophage-like J774.1 cells. From the water extract, 17 phenolic compounds were isolated and among them 15 are new for the water extract of propolis. Moreover, methyl ρ-hydroxydihydrocinnamate (9) and 1-(4-hydroxyphenyl)butane-1,3-dione (11) were isolated, for the first time, from propolis.
    CONCLUSIONS:
    Labdane-type diterpenes, flavonoids and some phenolic compounds possessed potent NO inhibitory activity. Coniferyl aldehyde (23) and Dimeric coniferyl acetate (33) showed the strongest NO inhibition with IC_50 values of 18.0 and 27.1 μM, respectively, which were stronger than the positive control, N^G-monomethyl-L-arginine (L-NMMA ; IC_50, 44.5 μM).
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2599 mL 11.2994 mL 22.5989 mL 45.1977 mL 56.4972 mL
    5 mM 0.452 mL 2.2599 mL 4.5198 mL 9.0395 mL 11.2994 mL
    10 mM 0.226 mL 1.1299 mL 2.2599 mL 4.5198 mL 5.6497 mL
    50 mM 0.0452 mL 0.226 mL 0.452 mL 0.904 mL 1.1299 mL
    100 mM 0.0226 mL 0.113 mL 0.226 mL 0.452 mL 0.565 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    芦荟新甙D; Aloeresin D CFN90717 105317-67-7 C29H32O11 = 556.56 20mg QQ客服:1413575084
    Tetrahymanol acetate; Tetrahymanol acetate CFN96624 2130-22-5 C32H54O2 = 470.79 5mg QQ客服:215959384
    去甲斑蝥素; Norcantharidin CFN99791 5442-12-6 C8H8O4 = 168.15 20mg QQ客服:1457312923
    Nigracin; Nigracin CFN99857 18463-25-7 C20H22O9 = 406.4 5mg QQ客服:1457312923

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