氯化失车菊素-3-O-桑布双糖苷

Cyanidin-3-O-sambubioside chloride

	产品编号	CFN92173
	CAS编号	33012-73-6
	分子式 = 分子量	C₂₆H₂₉ClO₁₅ = 617.0
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Flavonoids
	植物来源	The fruits of Vaccinium myrtillus
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

提供自定义包装

产品名称	产品编号	CAS编号	包装	QQ客服
氯化失车菊素-3-O-桑布双糖苷	CFN92173	33012-73-6	1mg	QQ客服：1413575084
氯化失车菊素-3-O-桑布双糖苷	CFN92173	33012-73-6	5mg	QQ客服：1413575084
氯化失车菊素-3-O-桑布双糖苷	CFN92173	33012-73-6	10mg	QQ客服：1413575084
氯化失车菊素-3-O-桑布双糖苷	CFN92173	33012-73-6	20mg	QQ客服：1413575084

存储与注意事项

1. 在您收到产品后请检查产品。如无问题，请将产品存入冰霜并且样品瓶保持密封，产品可以存放长达24个月（2-8摄氏度）。

2. 只要有可能，产品溶解后，您应该在同一天应用于您的实验。但是，如果您需要提前做预实验，或者需要全部溶解，我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。通常，这些可用于长达两周。使用前，打开样品瓶前，我们建议您将产品平衡至室温至少1小时。

3. 需要更多关于溶解度，使用和处理的建议？请发送电子邮件至：service@chemfaces.com

订购流程

1. 在线订购

请联系我们QQ客服

2. 电话订购

请拨打电话：
027-84237683 或 027-84237783

3. 邮件或传真订购

发送电子邮件到: manager@chemfaces.com 或
发送传真到：027-84254680

提供订购信息

为了方便客户的订购，请需要订购ChemFaces产品的客户，在下单的时候请提供下列信息，以供我们快速为您建立发货信息。

1. 产品编号（CAS No.或产品名称）

2. 发货地址

3. 联系方法 (联系人，电话）

4. 开票抬头 (如果需要发票的客户）

5. 发票地址（发货地址与发票地址不同）

发货时间

1. 付款方式为100%预付款客户，我们将在确认收到货款后当天或1-3个工作日发货。

2. 付款方式为月结的客户，我们承诺在收到订单后当天或1-3个工作日内发货。

3. 如果客户所需要的产品，需要重新生产，我们有权告知客户，交货时间需要延期。

ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Instituto Politécnico de Bragan?a (Portugal)

Warszawski Uniwersytet Medyczny (Poland)

Universidad de La Salle (Mexico)

St. Jude Children Research Hospital (USA)

Northeast Normal University Changchun (China)

Universit?t Basel (Switzerland)

Universidade Católica Portuguesa (Portugal)

Korea Intitute of Science and Technology (KIST) (Korea)

Instituto de Investigaciones Agropecuarias (Chile)

University of Fribourg (Switzerland)

University of Sao Paulo (Brazil)

Monash University Sunway Campus (Malaysia)

University Medical Center Mainz (Germany)

University of Wisconsin-Madison (USA)

More...

Description:

Cyanidin-3-O-sambubioside chloride is inhibitors of BPDE-induced NFκB activity. It inhibits the enzyme activity by competing with the substrate for the active site. Cyanidin-3-O-sambubioside chloride has antioxidant activity and free-radical-scavenging property.

Targets:

NF-kB | ROS

In vitro:

J Biomol Struct Dyn . 2018 Dec;36(16):4255-4269.

The inhibitory performance of flavonoid cyanidin-3-sambubiocide against H274Y mutation in H1N1 influenza virus[Pubmed: 29199545]

Abstract Oseltamivir (Tamiflu) is the most accepted antiviral drug that targets the neuraminidase (NA) protein to inhibit the viral release from the host cell. Few H1N1 influenza strains with the H274Y mutation creates drug resistance to oseltamivir. In this study, we report that flavonoid cyanidin-3-sambubiocide (C3S) compound acts as a potential inhibitor against H274Y mutation. The drug resistance mechanism and inhibitory activity of C3S and oseltamivir against wild-type (WT) and H274Y mutant-type (MT) have been studied and compared based on the results of molecular docking, molecular dynamics, and quantum chemical methods. Oseltamivir has been found less binding affinity with MT. C3S has more binding affinity with WT and MT proteins. From the dynamical study, the 150th loop of the MT protein has found more deformation than WT. A single H274Y mutation induces the conformational changes in the 150th loop which leads to produce more resistance to oseltamivir. The 150th cavity is more attractive target for C3S to stop the conformational changes in the MT, than 430th cavity of NA protein. The C3S is stabilized with MT by more number of hydrogen bonds than oseltamivir. The electrostatic interaction energy shows a stronger C3S binding with MT and this compound may be more effective against oseltamivir-resistant virus strains. Keywords: H274Y mutation; Influenza virus; drug resistance; molecular docking; molecular dynamic simulation.

Planta Med . 2013 Nov;79(17):1636-40.

Cyanidin-3-O-sambubioside from Acanthopanax sessiliflorus fruit inhibits metastasis by downregulating MMP-9 in breast cancer cells MDA-MB-231[Pubmed: 24214832]

Abstract Anthocyanins play an important role in physiological functions related to human health. This study aimed to investigate the inhibitory effect of cyanidin-3-O-sambubioside isolated from Acanthopanax sessiliflorus fruit on cancer cell metastasis. The inhibitory effect of cyanidin-3-O-sambubioside on angiogenesis was assessed by chorioallantoic membrane and tube formation assays. Cyanidin-3-O-sambubioside interrupted the formation of neovasculature and tube-like structures in a dose-dependent manner. It inhibited the wound healing migration and invasion of MDA-MB-231 cells through reconstituted extracellular matrix (Matrigel). Gelatin zymography revealed that cyanidin-3-O-sambubioside significantly decreased the secretion of matrix metalloproteinase-9 and inhibited matrix metalloproteinase-9 expression. In additional, cyanidin-3-O-sambubioside exerted an inhibitory effect on Akt phosphorylation. These results suggest that cyanidin-3-O-sambubioside inhibits metastasis processes, such as angiogenesis and invasion, in breast cancer cells through regulation of matrix metalloproteinase-9 activity. Georg Thieme Verlag KG Stuttgart · New York.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
矢车菊素-3-O-桑布双糖苷-5-O-葡萄糖苷; Cyanidin-3-O-sambubioside-5-O-glucoside chloride	CFN91865	53925-33-0	C₃₂H₃₉ClO₂₀ = 779.1	10mg	QQ客服：1457312923
Tricetinidin chloride; Tricetinidin chloride	CFN91190	65618-21-5	C₁₅H₁₁ClO₆ = 322.7	5mg	QQ客服：215959384
氯化矢车菊素; Cyanidin Chloride	CFN99741	528-58-5	C₁₅H₁₁O₆Cl = 322.70	20mg	QQ客服：2056216494
氯化矢车菊素-3-O-阿拉伯糖苷; Cyanidin-3-O-arabinoside chloride	CFN92041	111613-04-8	C₂₀H₁₉ClO₁₀ = 454.8	10mg	QQ客服：2056216494
矢车菊素-3-O-鼠李糖苷氯化物; Cyanidin-3-O-rhamnoside chloride	CFN91188	38533-30-1	C₂₁H₂₁ClO₁₀ = 468.8	5mg	QQ客服：1413575084
氯化失车菊素-3-O-半乳糖苷; Cyanidin-3-O-galactoside chloride	CFN92040	27661-36-5	C₂₁H₂₁ClO₁₁ = 484.9	10mg	QQ客服：1413575084
氯化失车菊素-3-O-葡萄糖苷; Cyanidin-3-O-glucoside chloride	CFN99740	7084-24-4	C₂₁H₂₁ClO₁₁ = 484.8	20mg	QQ客服：2056216494
氯化矢车菊素-3-O-(6''-丙二酰葡糖苷); Cyanidin-3-O-(6''-malonylglucoside) chloride	CFN91864	171828-62-9	C₂₄H₂₃ClO₁₄ = 570.9	5mg	QQ客服：3257982914
氯化失车菊素-3,5-O-双葡萄糖苷; Cyanidin-3,5-O-diglucoside chloride	CFN92138	2611-67-8	C₂₇H₃₁O₁₆Cl = 647.0	10mg	QQ客服：1457312923
氯化失车菊素-3-O-桑布双糖苷; Cyanidin-3-O-sambubioside chloride	CFN92173	33012-73-6	C₂₆H₂₉ClO₁₅ = 617.0	10mg	QQ客服：2056216494

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.6207 mL	8.1037 mL	16.2075 mL	32.4149 mL	40.5186 mL
5 mM	0.3241 mL	1.6207 mL	3.2415 mL	6.483 mL	8.1037 mL
10 mM	0.1621 mL	0.8104 mL	1.6207 mL	3.2415 mL	4.0519 mL
50 mM	0.0324 mL	0.1621 mL	0.3241 mL	0.6483 mL	0.8104 mL
100 mM	0.0162 mL	0.081 mL	0.1621 mL	0.3241 mL	0.4052 mL

氯化失车菊素-3-O-桑布双糖苷

Cyanidin-3-O-sambubioside chloride

信息支持

联系方式