黄芩素 7-O-beta-D-葡萄糖醛酸乙酯

Baicalein 7-O-beta-D-ethylglucuronide

	产品编号	CFN91993
	CAS编号	675624-38-1
	分子式 = 分子量	C₂₃H₂₂O₁₁ = 474.41
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Flavonoids
	植物来源	The roots of Scutellaria baicalensis Georgi
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
黄芩素 7-O-beta-D-葡萄糖醛酸乙酯	CFN91993	675624-38-1	1mg	QQ客服：3257982914
黄芩素 7-O-beta-D-葡萄糖醛酸乙酯	CFN91993	675624-38-1	5mg	QQ客服：3257982914
黄芩素 7-O-beta-D-葡萄糖醛酸乙酯	CFN91993	675624-38-1	10mg	QQ客服：3257982914
黄芩素 7-O-beta-D-葡萄糖醛酸乙酯	CFN91993	675624-38-1	20mg	QQ客服：3257982914

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

University of Wuerzburg (Germany)

Instituto Politécnico de Bragan?a (Portugal)

Funda??o Universitária de Desenvolvimento (Brazil)

Kazusa DNA Research Institute (Japan)

Universidade Católica Portuguesa (Portugal)

Texas A&M University (USA)

University of Bonn (Germany)

Sanford Burnham Medical Research Institute (USA)

Auburn University (USA)

Calcutta University (India)

Charles Sturt University (Denmark)

Universidade de Franca (Brazil)

Mahidol University (Thailand)

Medical University of Gdansk (Poland)

More...

Description:

Baicalein 7-O-beta-D-ethylglucuronide is a natural product from Scutellaria baicalensis Georgi.

In vitro:

Nat Prod Res. 2014;28(20):1772-6.

A new antioxidant flavone glycoside from Scutellaria baicalensis Georgi.[Pubmed: 24995563 ]

METHODS AND RESULTS:
A new flavone glycoside, wogonin 7-O-β-D-ethylglucuronide (1), together with a new natural flavone glycoside baicalein 7-O-β-D-ethylglucuronide (Baicalein 7-O-beta-D-ethylglucuronide,2) and four known analogues, wogonoside (3), wogonin (4), oroxylin A 7-O-β-D-methylglucuronide (5) and oroxylin A (6), was isolated from the roots of Scutellaria baicalensis Georgi. The structure elucidation of the new compound was primarily based on HR-ESI-MS, 1D and 2D NMR analyses.
CONCLUSIONS:
Compounds 1 and 3 inhibited FeSO4-Cys-induced liver homogenate lipid peroxidation with IC50 at 18.2 μM and 24.9 μM, respectively, and exhibited strong cytoprotective effects against H2O2-induced oxidative damage in human umbilical vein endothelial cells at low concentrations of 10.0 μM and 3.0 μM.

In vivo:

Journal of Applied Pharmaceutical Science, 2013, 3(12):46-51.

Evaluation of wound healing activity of baicalein-7-O- β-Dglucuronide isolated from Leucas aspera[Reference: WebLink]

Leucas aspera (Willd.) Linn. (Lamiaceae), commonly known as "Thumbai," is distributed throughout India. This study includes the isolation and characterization of flavonoids present in Leucas aspera flowers were compared wound healing activity with standard soframycin ointment.
METHODS AND RESULTS:
The plant materials were extracted with 95% methanol, petroleum ether, ethyl acetate, and were subjected to column and TLC chromatographic separation analysis. The chemical constituents isolated from the flowers of L. aspera were characterized based on chemical tests and spectral analysis such as UV and NMR spectroscopy. The structure of the isolated compound was confirmed as baicalein-7-O- β-D-glucuronide (baicalin). It has been investigated for wound healing activity by applying on the albino rats. A slow rate of healing was observed earlier which turns to very rapid on the 12th day. The histopathological examination provided additional evidence for the experimental wound healing studies. Protease is a biochemical marker and pH measured to support the wound healing activity.
CONCLUSIONS:
We conclude that the baicalin isolated with the flowers of L. aspera has better wound healing activity.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
去甲汉黄芩素-8-O-葡萄糖醛酸苷; Norwogonin-8-O-glucuronide	CFN95423	118525-47-6	C₂₁H₁₈O₁₁ = 446.4	5mg	QQ客服：3257982914
汉黄芩苷; Wogonoside	CFN99710	51059-44-0	C₂₂H₂₀O₁₁ = 460.39	20mg	QQ客服：1413575084
穿心莲黄酮苷C; Andrographidine C	CFN97852	113963-39-6	C₂₃H₂₄O₁₀ = 460.44	5mg	QQ客服：2159513211
5-Hydroxy-7,8-dimethoxy (2R)-flavanone-5-O-beta-D-glucopyranoside; 5-Hydroxy-7,8-dimethoxy (2R)-flavanone-5-O-beta-D-glucopyranoside	CFN95209	942626-74-6	C₂₃H₂₆O₁₀ = 462.5	10mg	QQ客服：1413575084
穿心莲黄酮苷A; Andrographidine A	CFN95210	113963-37-4	C₂₃H₂₆O₁₀ = 462.5	10mg	QQ客服：2159513211
白杨素-7-O-龙胆二糖苷; Chrysin 7-O-beta-gentiobioside	CFN90833	88640-89-5	C₂₇H₃₀O₁₄ = 578.5	5mg	QQ客服：1457312923
木蝴蝶苷A; Oroxin A	CFN99712	57396-78-8	C₂₁H₂₀O₁₀ = 432.38	20mg	QQ客服：1413575084
黄芩苷; Baicalin	CFN99111	21967-41-9	C₂₁H₁₈O₁₁ = 446.37	20mg	QQ客服：215959384
黄芩苷甲酯; Baicalin methyl ester	CFN92283	82475-03-4	C₂₂H₂₀O₁₁ = 460.4	20mg	QQ客服：3257982914
黄芩素 7-O-beta-D-葡萄糖醛酸乙酯; Baicalein 7-O-beta-D-ethylglucuronide	CFN91993	675624-38-1	C₂₃H₂₂O₁₁ = 474.41	5mg	QQ客服：1413575084

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.1079 mL	10.5394 mL	21.0788 mL	42.1576 mL	52.697 mL
5 mM	0.4216 mL	2.1079 mL	4.2158 mL	8.4315 mL	10.5394 mL
10 mM	0.2108 mL	1.0539 mL	2.1079 mL	4.2158 mL	5.2697 mL
50 mM	0.0422 mL	0.2108 mL	0.4216 mL	0.8432 mL	1.0539 mL
100 mM	0.0211 mL	0.1054 mL	0.2108 mL	0.4216 mL	0.527 mL