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  • 绣球酚

    Hydrangenol

    绣球酚
    产品编号 CFN98745
    CAS编号 480-47-7
    分子式 = 分子量 C15H12O4 = 256.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Hydrangea hortensia
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    绣球酚 CFN98745 480-47-7 1mg QQ客服:1413575084
    绣球酚 CFN98745 480-47-7 5mg QQ客服:1413575084
    绣球酚 CFN98745 480-47-7 10mg QQ客服:1413575084
    绣球酚 CFN98745 480-47-7 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • National Hellenic Research Foundation (Greece)
  • Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)
  • Wroclaw Medical University (Poland)
  • University of Wollongong (Australia)
  • Universidad de Buenos Aires (Argentina)
  • Universidad Veracuzana (Mexico)
  • Utrecht University (Netherlands)
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  • University of Virginia (USA)
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  • University of Ioannina (Greece)
  • Texas A&M University (USA)
  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
  • University of Pretoria (South Africa)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Int J Biol Macromol.2018, 112:1093-1103
  • ACS Pharmacol. Transl. Sci.2023, 3c00129.
  • PLoS One.2021, 16(6):e0248479.
  • Regul Toxicol Pharmacol.2023, 142:105433.
  • J Cell Physiol.2021, 236(3):1950-1966.
  • Appl. Sci. 2021, 11(1),14.
  • Pathogens.2018, 7(3):E62
  • bioRxiv2021, 462065.
  • Heliyon.2022, 8(12):e12031.
  • The Journal of Animal & Plant Sciences.2020, 30(6):1366-1373
  • Enzyme Microb Technol.2022, 153:109941.
  • Molecules.2021, 26(6):1738.
  • Evid Based Complement Alternat Med.2018, 2018:1073509
  • bioRxiv - Molecular Biology2023, 535548.
  • J Cell Biochem.2018, 119(2):2231-2239
  • J Pharm Anal.2016, 6(6):363-373
  • Cell Metab.2020, S1550-4131(20)30002-4
  • Int J Mol Sci.2018, 19(9):E2601
  • Industrial Crops and Products2018, 353-362
  • Biochem Biophys Res Commun.2020, 522(4):1052-1058
  • Int J Mol Sci.2021, 22(17):9400.
  • Anal Bioanal Chem. 2016, 408(15)
  • Biomolecules.2023, 13(2):227.
  • ...
  • 生物活性
    Description: Hydrangenol is a strong contact sensitizer found in hydrangea (Hydrangea sp.; Hydrangeaceae), it can significantly inhibit the passive cutaneous anaphylaxis (PCA) reaction, it has antiallergic activity. Hydrangenol has anti-inflammatory, and antifungal activities,it can attenuate NO production and inducible NO synthase expression in lipopolysaccharide (LPS)-stimulated BV2 microglial cells by inhibiting NF-κB activation and by stimulating the Nrf2-mediated HO-1 signaling pathway. Hydrangenol has antifungal activity.
    Targets: NO | NOS | NF-kB | HO-1 | Nrf2 | Antifection
    In vitro:
    Biol Pharm Bull. 1999 Aug;22(8):870-2.
    Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats.[Pubmed: 10480329]

    METHODS AND RESULTS:
    We examined the antiallergic effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F isolated from the processed leaves (Hydrangeae Dulcis Folium) and dried leaves of Hydrangea macrophylla SERINGE var. thunbergii MAKINO using the passive cutaneous anaphylaxis (PCA) reaction. With the exception of phyllodulcin, these constituents were found to significantly inhibit the PCA reaction.
    CONCLUSIONS:
    Although thunberginol A showed the most potent inhibitory effect, hydrangenol was considered to be the principal antiallergic component in the processed leaves, after taking into account their contents.
    Chem Pharm Bull (Tokyo). 1981 Sep;29(9):2689-91.
    Antifungal activity of oosponol, oospolactone, phyllodulcin, hydrangenol, and some other related compounds.[Pubmed: 7349286]

    METHODS AND RESULTS:
    Antifungal activity of oosponol, oospolactone, phyllodulcin, hydrangenol, and some other related compounds.
    Contact Dermatitis. 1991 Mar;24(3):233-5.
    Hydrangenol, a strong contact sensitizer found in hydrangea (Hydrangea sp.; Hydrangeaceae).[Pubmed: 1868712]

    METHODS AND RESULTS:
    Hydrangenol, a strong contact sensitizer found in hydrangea (Hydrangea sp.; Hydrangeaceae).
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.9017 mL 19.5084 mL 39.0168 mL 78.0336 mL 97.5419 mL
    5 mM 0.7803 mL 3.9017 mL 7.8034 mL 15.6067 mL 19.5084 mL
    10 mM 0.3902 mL 1.9508 mL 3.9017 mL 7.8034 mL 9.7542 mL
    50 mM 0.078 mL 0.3902 mL 0.7803 mL 1.5607 mL 1.9508 mL
    100 mM 0.039 mL 0.1951 mL 0.3902 mL 0.7803 mL 0.9754 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    绣球酚; Hydrangenol CFN98745 480-47-7 C15H12O4 = 256.3 5mg QQ客服:3257982914
    绣球酚8-O-葡萄糖甙; Hydrangenol 8-O-glucoside CFN97153 67600-94-6 C21H22O9 = 418.4 5mg QQ客服:1457312923
    (3R)-绣球酚8-O-葡萄糖甙五乙酸酯; (3R)-Hydrangenol 8-O-glucoside pentaacetate CFN99230 113270-98-7 C31H32O14 = 628.6 5mg QQ客服:1457312923
    (3S)-绣球酚8-O-葡萄糖甙五乙酸酯; (3S)-Hydrangenol 8-O-glucoside pentaacetate CFN99231 113270-99-8 C31H32O14 = 628.6 5mg QQ客服:3257982914
    Thunberginol C; Thunberginol C CFN99610 147517-06-4 C15H12O5 = 272.3 5mg QQ客服:215959384
    仙鹤草内酯; Agrimonolide CFN98073 21499-24-1 C18H18O5 = 314.3 5mg QQ客服:3257982914
    仙鹤草内酯-6-O-葡萄糖甙; Agrimonolide 6-O-glucoside CFN99374 126223-29-8 C24H28O10 = 476.5 5mg QQ客服:1413575084
    5,6-Desmethylenedioxy-5-methoxyaglalactone; 5,6-Desmethylenedioxy-5-methoxyaglalactone CFN89361 922169-96-8 C17H16O5 = 300.30 5mg QQ客服:1413575084
    6,8-Di-O-methylcitreoisocoumarin; 6,8-Di-O-methylcitreoisocoumarin CFN89086 908098-80-6 C16H18O6 = 306.31 5mg QQ客服:3257982914

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