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  • 绣球酚8-O-葡萄糖甙

    Hydrangenol 8-O-glucoside

    绣球酚8-O-葡萄糖甙
    产品编号 CFN97153
    CAS编号 67600-94-6
    分子式 = 分子量 C21H22O9 = 418.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Hydrangea paniculata
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    绣球酚8-O-葡萄糖甙 CFN97153 67600-94-6 1mg QQ客服:3257982914
    绣球酚8-O-葡萄糖甙 CFN97153 67600-94-6 5mg QQ客服:3257982914
    绣球酚8-O-葡萄糖甙 CFN97153 67600-94-6 10mg QQ客服:3257982914
    绣球酚8-O-葡萄糖甙 CFN97153 67600-94-6 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Maryland School of Medicine (USA)
  • University of Leipzig (Germany)
  • Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)
  • Universidad de Buenos Aires (Argentina)
  • Worcester Polytechnic Institute (USA)
  • Universidade Federal de Goias (UFG) (Brazil)
  • University of Pretoria (South Africa)
  • Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
  • Washington State University (USA)
  • Warszawski Uniwersytet Medyczny (Poland)
  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
  • Seoul National University of Science and Technology (Korea)
  • Osmania University (India)
  • National Cancer Institute (USA)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Journal of Chromatography A2020, 460942
  • Int J Mol Sci.2022, 23(5):2796.
  • J Inflamm Res.2022, 15:5347-5359.
  • Antioxidants (Basel).2022, 11(1):171.
  • J Sep Sci.2018, 41(9):1938-1946
  • Microchemical Journal2022, 182: 107874.
  • Bull. Natl. Mus. Nat. Sci.2021, 47(2),109-114.
  • Plant Cell Tiss Org2020, 1-16
  • J of Physics Conference Series2019, 1349(1)
  • Phytochem Anal.2022, doi: 10.1002
  • Int J Immunopathol Pharmacol.2019, 33:2058738419857537
  • Chin J Appl. Physiol.2019, 35(3):283-288
  • Appl. Sci.2022, 12(4), 2032.
  • J Ethnopharmacol.2022, 291:115159.
  • J of App. Res. on Med&Aromatic Plants2020, 100291.
  • Int J Mol Sci.2022, 23(15):8687.
  • Inflammation.2022, 45(6):2529-2543.
  • GENENCELL2023, 25:4356740
  • Front Pharmacol.2021, 12:744624.
  • Nutrients.2021, 13(8):2901.
  • Front Plant Sci.2022, 12:811166.
  • Environ Toxicol Pharmacol.2019, 66:109-115
  • Int J Mol Sci.2021, 22(12):6466.
  • ...
  • 生物活性
    Description: Hydrangenol 8-O-glucoside may have anti-inflammary activity.
    Targets: NF-kB | TNF-α | IL Receptor
    In vitro:
    Molecules. 2015 Dec 30;21(1):E43.
    Turkish Scorzonera Species Extracts Attenuate Cytokine Secretion via Inhibition of NF-κB Activation, Showing Anti-Inflammatory Effect in Vitro.[Pubmed: 26729082]
    Scorzonera species are used in different folk medicines to combat many diseases, including the illnesses connected with inflammation. Previous experiments showed anti-inflammatory activity of Scorzonera extracts in vivo. S. latifolia, S. cana var. jacquiniana, S. tomentosa, S. mollis ssp. szowitsii, S. eriophora, S. incisa, S. cinerea, and S. parviflora extracts were, therefore, evaluated for their inhibitory activities of TNF-α and IL-1β production, and NF-κB nuclear translocation in THP-1 macrophages.
    METHODS AND RESULTS:
    The HPLC analysis was carried out to elucidate and to compare the composition of these extracts. Major compounds of the tested extracts have been isolated using different chromatographic techniques and further tested for their inhibitory activities on TNF-α and IL-1β production. Several extracts showed promising anti-inflammatory activity in these in vitro tests. Results of HPLC analysis revealed chlorogenic acid as a compound present in all tested extracts. Hyperoside, quercetin-3-O-β-d-glucoside and rutin were also present in varying amount in some Scorzonera species analyzed. Furthermore, eight phenolics which were identified as quercetin-3-O-β-d-glucoside (1), hyperoside (2), Hydrangenol 8-O-glucoside (3), swertisin (4), 7-methylisoorientin (5), 4,5-O-dicaffeoyl-quinic acid (6), 3,5-di-O-caffeoyl-quinic acid (7), and chlorogenic acid (8) have been isolated as major phenolic compounds of the tested extracts and, together with eight terpenoids (9-16) previously obtained from different Scorzonera species, have been tested for the inhibition of TNF-α production, unfortunately with no activity comparable with standard.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.3901 mL 11.9503 mL 23.9006 mL 47.8011 mL 59.7514 mL
    5 mM 0.478 mL 2.3901 mL 4.7801 mL 9.5602 mL 11.9503 mL
    10 mM 0.239 mL 1.195 mL 2.3901 mL 4.7801 mL 5.9751 mL
    50 mM 0.0478 mL 0.239 mL 0.478 mL 0.956 mL 1.195 mL
    100 mM 0.0239 mL 0.1195 mL 0.239 mL 0.478 mL 0.5975 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    绣球酚; Hydrangenol CFN98745 480-47-7 C15H12O4 = 256.3 5mg QQ客服:215959384
    绣球酚8-O-葡萄糖甙; Hydrangenol 8-O-glucoside CFN97153 67600-94-6 C21H22O9 = 418.4 5mg QQ客服:1457312923
    (3R)-绣球酚8-O-葡萄糖甙五乙酸酯; (3R)-Hydrangenol 8-O-glucoside pentaacetate CFN99230 113270-98-7 C31H32O14 = 628.6 5mg QQ客服:1413575084
    (3S)-绣球酚8-O-葡萄糖甙五乙酸酯; (3S)-Hydrangenol 8-O-glucoside pentaacetate CFN99231 113270-99-8 C31H32O14 = 628.6 5mg QQ客服:3257982914
    Thunberginol C; Thunberginol C CFN99610 147517-06-4 C15H12O5 = 272.3 5mg QQ客服:2159513211
    仙鹤草内酯; Agrimonolide CFN98073 21499-24-1 C18H18O5 = 314.3 5mg QQ客服:3257982914
    仙鹤草内酯-6-O-葡萄糖甙; Agrimonolide 6-O-glucoside CFN99374 126223-29-8 C24H28O10 = 476.5 5mg QQ客服:3257982914
    5,6-Desmethylenedioxy-5-methoxyaglalactone; 5,6-Desmethylenedioxy-5-methoxyaglalactone CFN89361 922169-96-8 C17H16O5 = 300.30 5mg QQ客服:2056216494
    6,8-Di-O-methylcitreoisocoumarin; 6,8-Di-O-methylcitreoisocoumarin CFN89086 908098-80-6 C16H18O6 = 306.31 5mg QQ客服:3257982914

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