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  • 二氢甘草异黄酮

    Dihydrolicoisoflavone

    二氢甘草异黄酮
    产品编号 CFN95073
    CAS编号 164163-92-2
    分子式 = 分子量 C20H20O6 = 356.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The roots of Glycyrrhiza uralensis.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    二氢甘草异黄酮 CFN95073 164163-92-2 1mg QQ客服:3257982914
    二氢甘草异黄酮 CFN95073 164163-92-2 5mg QQ客服:3257982914
    二氢甘草异黄酮 CFN95073 164163-92-2 10mg QQ客服:3257982914
    二氢甘草异黄酮 CFN95073 164163-92-2 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Helsinki (Finland)
  • University of Brasilia (Brazil)
  • Chungnam National University (Korea)
  • Charles University in Prague (Czech Republic)
  • University of Zurich (Switzerland)
  • Martin Luther University of Halle-Wittenberg (Germany)
  • Ateneo de Manila University (Philippines)
  • Harvard University (USA)
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  • Lund University (Sweden)
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  • University of Wuerzburg (Germany)
  • Universidade Católica Portuguesa (Portugal)
  • University of Pretoria (South Africa)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Foods.2022, 11(6):882.
  • Nutr Cancer.2022, 1-13.
  • Int J Cosmet Sci.2023, 45(2):155-165.
  • FASEB J.2022, 36(7):e22387.
  • Chem Biol Interact.2019, 315:108910
  • Saudi Pharm J.2019, 27(1):145-153
  • Life Sci.2021, 286:120019.
  • Evid Based Complement Alternat Med.2021, 8855980.
  • Nat Prod Sci.2016, 22(2)
  • Phytomedicine.2022, 99:153997.
  • Pharmaceutics.2021, 13(7):1028.
  • Curr Issues Mol Biol.2023, 45(3):2136-2156.
  • J Agric Food Chem.2019, 67(27):7748-7754
  • Front Pharmacol.2023, 14:1095083.
  • Drug Des Devel Ther.2020, 14:969-976.
  • Evid Based Complement Alternat Med.2017, 2017:1401279
  • J. Food Composition and Anal.2022, V 109:104482.
  • Industrial Crops and Products2021, 163:113313.
  • Separation Science Plus2022, sscp.202200048.
  • J of Dentistry & Oral Health2019, 2641-1962
  • J AOAC Int.2023, 106(1):56-64.
  • J Breast Cancer.2015, 18(2):112-118
  • Chin Med.2022, 17(1):66.
  • ...
  • 生物活性
    Description: Dihydrolicoisoflavone A possesses weaker anti-H. pylori activity, it may be useful chemopreventive agents for peptic ulcer or gastric cancer in H. pylori-infected individuals.
    Targets: Antifection
    In vitro:
    Life Sci. 2002 Aug 9;71(12):1449-63.
    Anti-Helicobacter pylori flavonoids from licorice extract.[Pubmed: 12127165]
    Licorice is the most used crude drug in Kampo medicines (traditional Chinese medicines modified in Japan). The extract of the medicinal plant is also used as the basis of anti-ulcer medicines for treatment of peptic ulcer. Among the chemical constituents of the plant, glabridin and glabrene (components of Glycyrrhiza glabra), licochalcone A (G. inflata), licoricidin and licoisoflavone B (G. uralensis) exhibited inhibitory activity against the growth of Helicobacter pylori in vitro. These flavonoids also showed anti-H. pylori activity against a clarithromycin (CLAR) and amoxicillin (AMOX)-resistant strain. We also investigated the methanol extract of G. uralensis. From the extract, three new isoflavonoids (3-arylcoumarin, pterocarpan, and isoflavan) with a pyran ring, gancaonols A[bond]C, were isolated together with 15 known flavonoids.
    CONCLUSIONS:
    Among these compounds, vestitol, licoricone, 1-methoxyphaseollidin and gancaonol C exhibited anti-H. pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. Glycyrin, formononetin, isolicoflavonol, glyasperin D, 6,8-diprenylorobol, gancaonin I, dihydrolicoisoflavone A, and gancaonol B possessed weaker anti-H. pylori activity. These compounds may be useful chemopreventive agents for peptic ulcer or gastric cancer in H. pylori-infected individuals.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8058 mL 14.0292 mL 28.0584 mL 56.1167 mL 70.1459 mL
    5 mM 0.5612 mL 2.8058 mL 5.6117 mL 11.2233 mL 14.0292 mL
    10 mM 0.2806 mL 1.4029 mL 2.8058 mL 5.6117 mL 7.0146 mL
    50 mM 0.0561 mL 0.2806 mL 0.5612 mL 1.1223 mL 1.4029 mL
    100 mM 0.0281 mL 0.1403 mL 0.2806 mL 0.5612 mL 0.7015 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Lupinalbin A; Lupinalbin A CFN80045 98094-87-2 C15H8O6 = 284.03 5mg QQ客服:2159513211
    2-羟基异樱黄素; Barpisoflavone A CFN97861 101691-27-4 C16H12O6 = 300.27 5mg QQ客服:1413575084
    木豆异黄酮; 2',4',5-三羟基-7-甲氧基异黄酮; Cajanin CFN98419 32884-36-9 C16H12O6 = 300.3 5mg QQ客服:2159513211
    高淝任素; Homoferreirin CFN97891 482-01-9 C17H16O6 = 316.3 5mg QQ客服:2056216494
    砂生槐异黄酮 A; Sophoraisoflavone A CFN96513 117204-81-6 C20H16O6 = 352.34 5mg QQ客服:2056216494
    甘草异黄烷酮; Licoisoflavanone CFN96544 66067-26-3 C20H18O6 = 354.36 5mg QQ客服:1457312923
    粗毛甘草素F; Glyasperin F CFN94013 145382-61-2 C20H18O6 = 354.35 5mg QQ客服:1457312923
    二氢甘草异黄酮; Dihydrolicoisoflavone CFN95073 164163-92-2 C20H20O6 = 356.4 5mg QQ客服:1413575084
    5,7,2',4'-Tetrahydroxy-8,3'-di(γ,γ-dimethylallyl)-isoflavanone; 5,7,2',4'-Tetrahydroxy-8,3'-di(gamma,gamma-dimethylallyl)-isoflavanone CFN95084 141846-47-1 C25H28O6 = 424.5 5mg QQ客服:2159513211
    2',4'-二羟基-7-甲氧基异黄酮; 5-Deoxycajanin CFN97240 7622-53-9 C16H12O5 = 284.3 5mg QQ客服:215959384

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