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  • Lupinalbin A

    Lupinalbin A

    Lupinalbin A
    产品编号 CFN80045
    CAS编号 98094-87-2
    分子式 = 分子量 C15H8O6 = 284.03
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Lupinus albus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Lupinalbin A CFN80045 98094-87-2 1mg QQ客服:1457312923
    Lupinalbin A CFN80045 98094-87-2 5mg QQ客服:1457312923
    Lupinalbin A CFN80045 98094-87-2 10mg QQ客服:1457312923
    Lupinalbin A CFN80045 98094-87-2 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Ioannina (Greece)
  • Indian Institute of Science (India)
  • Universidad de Buenos Aires (Argentina)
  • Harvard University (USA)
  • Center for protein Engineering (CIP) (Belgium)
  • University of Padjajaran (Indonesia)
  • Utrecht University (Netherlands)
  • University of Canterbury (New Zealand)
  • Cornell University (USA)
  • University of Wollongong (Australia)
  • University of Leipzig (Germany)
  • University of Queensland (Australia)
  • University of Pretoria (South Africa)
  • The University of Newcastle (Australia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Phytomedicine.2022, 100:154036.
  • Antioxidants (Basel).2021, 10(11):1831.
  • Kasetsart University2022, ethesis.1144.
  • Molecules2021, 26(1),230
  • Journal of Functional Foods2022, 96: 105216.
  • Sci Rep.2018, 8(1)
  • Plos One.2020, 10.1371
  • Sci Rep.2021, 11(1):10931.
  • Vietnam Journal of Food Control2022, 5(3):pp.390-401.
  • Nat Prod Communications2018, 10.1177
  • Food Funct.2021, 12(13):5892-5902.
  • Int J Mol Sci.2020, 21(19):7209.
  • J Integr Plant Biol.2023, 13564.
  • In Vitro Cellular & Developmental Biology - Plant2022, 58:972-988.
  • PLoS One.2020, 15(2):e0220084.
  • Foods.2021, 10(6):1378.
  • SRM Institute of Sci&Tech2022, 34(1): 32-37
  • African J. Agricultural Research 2017, 12(13):1164-1168
  • Antioxidants (Basel).2022, 11(12):2496.
  • J Nat Med.2018, 72(3):734-744
  • Journal of Food Hygiene and Safety2019, 34(5):413-420
  • Phytother Res.2018, 32(5):923-932
  • J Cell Mol Med.2021, 25(5):2645-2654.
  • ...
  • 生物活性
    Description: Lupinalbin A as the most potent estrogen receptor α- and aryl hydrocarbon receptor agonist in Eriosema laurentii de Wild. (Leguminosae). It exerts anti-inflammatory effects via the inhibition of pro-inflammatory cytokines and blocking of IFN-β/STAT1 pathway activation.
    Targets: STAT | IFN-γ | IL Receptor | Estrogen receptor | Progestogen receptor
    In vitro:
    Molecules. 2018 Mar 6;23(3). pii: E583.
    Anti-Inflammatory Effect of Lupinalbin A Isolated from Apios americana on Lipopolysaccharide-Treated RAW264.7 Cells.[Pubmed: 29509670 ]
    Apios americana, a leguminous plant, is used as food in some countries. Although the biological activities of Apios extract have been reported, there have been no reports about the anti-inflammatory mechanism of Lupinalbin A on the RAW264.7 cells.
    METHODS AND RESULTS:
    In this study, we investigated the anti-inflammatory effect of A. americana Lupinalbin A on lipopolysaccharide (LPS)-treated RAW264.7 cells. Lupinalbin A significantly inhibited nitric oxide production and inducible nitric oxide synthase expression in LPS-treated RAW264.7 cells. The expression of cytokines, including interleukin-6, tumor necrosis factor-α, and chemokine of monocyte chemoattractant protein, was reduced under Lupinalbin A exposure in LPS-treated RAW264.7 cells. In addition, Lupinalbin A significantly decreased LPS-induced interferon (IFN)-β production and STAT1 protein levels in RAW264.7 cells.
    CONCLUSIONS:
    Taken together, these results suggest that A. americana Lupinalbin A exerts anti-inflammatory effects via the inhibition of pro-inflammatory cytokines and blocking of IFN-β/STAT1 pathway activation.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.5208 mL 17.6038 mL 35.2075 mL 70.4151 mL 88.0189 mL
    5 mM 0.7042 mL 3.5208 mL 7.0415 mL 14.083 mL 17.6038 mL
    10 mM 0.3521 mL 1.7604 mL 3.5208 mL 7.0415 mL 8.8019 mL
    50 mM 0.0704 mL 0.3521 mL 0.7042 mL 1.4083 mL 1.7604 mL
    100 mM 0.0352 mL 0.176 mL 0.3521 mL 0.7042 mL 0.8802 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    砂生槐异黄酮 A; Sophoraisoflavone A CFN96513 117204-81-6 C20H16O6 = 352.34 5mg QQ客服:215959384
    甘草异黄烷酮; Licoisoflavanone CFN96544 66067-26-3 C20H18O6 = 354.36 5mg QQ客服:3257982914
    粗毛甘草素F; Glyasperin F CFN94013 145382-61-2 C20H18O6 = 354.35 5mg QQ客服:1413575084
    二氢甘草异黄酮; Dihydrolicoisoflavone CFN95073 164163-92-2 C20H20O6 = 356.4 5mg QQ客服:2159513211
    5,7,2',4'-Tetrahydroxy-8,3'-di(γ,γ-dimethylallyl)-isoflavanone; 5,7,2',4'-Tetrahydroxy-8,3'-di(gamma,gamma-dimethylallyl)-isoflavanone CFN95084 141846-47-1 C25H28O6 = 424.5 5mg QQ客服:3257982914
    2',4'-二羟基-7-甲氧基异黄酮; 5-Deoxycajanin CFN97240 7622-53-9 C16H12O5 = 284.3 5mg QQ客服:2056216494
    2',4',5,7-四羟基异黄烷酮; Dalbergioidin CFN97931 30368-42-4 C15H12O6 = 288.3 5mg QQ客服:3257982914
    2'-羟基染料木素; 2'-Hydroxygenistein CFN99257 1156-78-1 C15H10O6 = 286.2 5mg QQ客服:2056216494
    Lupinalbin A; Lupinalbin A CFN80045 98094-87-2 C15H8O6 = 284.03 5mg QQ客服:215959384
    2-羟基异樱黄素; Barpisoflavone A CFN97861 101691-27-4 C16H12O6 = 300.27 5mg QQ客服:3257982914

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