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  • D(+)-阿拉伯糖醇

    D-arabinitol

    D(+)-阿拉伯糖醇
    产品编号 CFN98779
    CAS编号 488-82-4
    分子式 = 分子量 C5H12O5 = 152.1
    产品纯度 >=98%
    物理属性 Cryst.
    化合物类型 Miscellaneous
    植物来源 The barks of Eucommia ulmoides Oliver
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    D(+)-阿拉伯糖醇 CFN98779 488-82-4 10mg QQ客服:1457312923
    D(+)-阿拉伯糖醇 CFN98779 488-82-4 20mg QQ客服:1457312923
    D(+)-阿拉伯糖醇 CFN98779 488-82-4 50mg QQ客服:1457312923
    D(+)-阿拉伯糖醇 CFN98779 488-82-4 100mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • Nanjing University of Chinese Medicine (China)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J of Essential Oil Research2019, 1677272
  • Cancer Lett. 2023, 18:216584.
  • Oncotarget.2015, 6(31):30831-49
  • J Ethnopharmacol.2017, 198:205-213
  • Mediators Inflamm. 2016, 2016:6189590
  • Analytical Letters.2020, doi 10.1008
  • 2023, 24(6):5769.Int J Mol Sci.
  • Food Funct.2021, 12(4):1469-1481.
  • J Ginseng Res.2022, 46(1):104-114.
  • Evid Based Complement Alternat Med.2021, 2021:5319584.
  • Evid Based Complement Alternat Med.2017, 2017:1583185
  • Cells.2023, 12(1):168.
  • J Med Food.2019, 22(10):1067-1077
  • J Colloid Interface Sci.2022, 622:298-308.
  • J of Applied Biological Chem.2020, 63(2):147-152
  • Int J Mol Sci.2020, 21(22):8816.
  • Theranostics.2023, 13(9):3103-3116.
  • Fitoterapia.2021, 153:104995.
  • Nat Prod Commun.2014, 9(5):679-82
  • Pharmaceuticals (Basel).2021, 14(6):588.
  • Onco Targets Ther.2017, 10:3467-3474
  • Food Funct.2020, 11(2):1322-1333.
  • Mol Cells.2018, 41(8):771-780
  • ...
  • 生物活性
    Description: D-arabinitol is a marker for the diagnosis of disseminated candidiasis and for monitoring response to antifungal therapy.
    In vivo:
    J Med Vet Mycol. 1994;32(3):205-15.
    Serum D-arabinitol measured by automated quantitative enzymatic assay for detection and therapeutic monitoring of experimental disseminated candidiasis: correlation with tissue concentrations of Candida albicans.[Pubmed: 7965491]
    In order to further understand serum D-arabinitol (DA) as a marker for the diagnosis of disseminated candidiasis and for monitoring response to antifungal therapy, we studied the serum levels of this Candida carbohydrate metabolite by rapid automated enzymatic assay in rabbits with experimental disseminated candidiasis. As a correction for renal impairment, data were expressed as serum D-arabinitol/creatinine ratio (D-arabinitol/Cr). Serum creatinine concentrations were determined from the same sample with the same instrument, thereby allowing rapid determination of the D-arabinitol/Cr within one laboratory.
    METHODS AND RESULTS:
    The D-arabinitol/Cr was determined in 321 samples from 132 rabbits. The mean serum D-arabinitol/Cr in 31 normal non-infected rabbits was 1.51 +/- 0.2 microM mg-1 dl-1. Among 84 rabbits with disseminated candidiasis and pre-terminal samples, there was a direct correlation between D-arabinitol/Cr and tissue concentration of Candida albicans (r = 0.80; P < 0.001). A threshold of elevated D-arabinitol/Cr (> or = 3.0 microM mg-1 dl-1) was evident in rabbits with a tissue concentration of C. albicans > or = 3 x 10(4) colony forming units (CFU) g-1. Elevated D-arabinitol/Cr was detected in 48 (89%) of 54 rabbits at a C. albicans tissue concentration of > or = 3 x 10(4) CFU g-1 vs. The relationship between the tissue response to antifungal therapy and change in D-arabinitol/Cr was then further analysed. Ten (91%) of 11 rabbits with a tissue-proven response to antifungal therapy (defined as > or = 10(2)-fold reduction of CFU g-1 in comparison to untreated controls) had a > 50% reduction in elevated D-arabinitol/Cr levels. By comparison, 10 (83%) of 12 treated rabbits with no response to therapy had persistently elevated D-arabinitol/Cr levels (P < 0.001).
    CONCLUSIONS:
    These findings provide an experimental basis for understanding the patterns of expression of serum D-arabinitol in disseminated candidiasis and further indicate that serial D-arabinitol/Cr measurements may be useful for diagnosis and therapeutic monitoring of disseminated candidiasis.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 6.5746 mL 32.8731 mL 65.7462 mL 131.4924 mL 164.3655 mL
    5 mM 1.3149 mL 6.5746 mL 13.1492 mL 26.2985 mL 32.8731 mL
    10 mM 0.6575 mL 3.2873 mL 6.5746 mL 13.1492 mL 16.4366 mL
    50 mM 0.1315 mL 0.6575 mL 1.3149 mL 2.6298 mL 3.2873 mL
    100 mM 0.0657 mL 0.3287 mL 0.6575 mL 1.3149 mL 1.6437 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    N-乙酰神经氨酸; N-Acetylneuraminic acid CFN90045 131-48-6 C11H19NO9 = 309.27 20mg QQ客服:2056216494
    甘露醇; D-Mannitol CFN90046 69-65-8 C6H14O6 = 182.17 20mg QQ客服:1413575084
    卫矛醇; Dulcitol CFN80242 608-66-2 C6H14O6 = 182.07 5mg QQ客服:2159513211
    蒜糖醇; Allitol CFN98777 488-44-8 C6H14O6 = 182.2 5mg QQ客服:2159513211
    D(+)-阿拉伯糖醇; D-arabinitol CFN98779 488-82-4 C5H12O5 = 152.1 20mg QQ客服:1413575084
    硫酸氨基葡萄糖; Glucosamine sulfate CFN99193 29031-19-4 C6H15NO9S = 277.25 20mg QQ客服:1457312923
    木糖醇; Xylitol CFN99510 87-99-0 C5H12O5 = 152.15 20mg QQ客服:215959384
    赤藓糖醇; Erythritol CFN99620 149-32-6 C4H10O4 = 122.1 20mg QQ客服:1413575084
    D-甘露糖; D-Mannose CFN91717 3458-28-4 C6H12O6 = 180.16 20mg QQ客服:3257982914

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