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  • α-蒎烯

    Alpha-pinene

    α-蒎烯
    产品编号 CFN93285
    CAS编号 80-56-8
    分子式 = 分子量 C10H16 = 136.2
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Monoterpenoids
    植物来源 The heartwoods of Pinus armandii Franch.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
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    α-蒎烯 CFN93285 80-56-8 10mg QQ客服:2159513211
    α-蒎烯 CFN93285 80-56-8 20mg QQ客服:2159513211
    α-蒎烯 CFN93285 80-56-8 50mg QQ客服:2159513211
    α-蒎烯 CFN93285 80-56-8 100mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Aveiro University (Portugal)
  • Heinrich-Heine-University Düsseldorf (Germany)
  • Chungnam National University (Korea)
  • University of Dicle (Turkey)
  • Complutense University of Madrid (Spain)
  • Agricultural Research Organization (ARO) (Israel)
  • Shanghai Institute of Organic Chemistry (China)
  • Universiti Malaysia Pahang (Malaysia)
  • Leibniz Institute of Plant Biochemistry (Germany)
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  • University of Auckland (New Zealand)
  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
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  • Cornell University (USA)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Proc Natl Acad Sci USA.2016, 113(30):E4407-1
  • J Med Food.2016, 19(12):1155-1165
  • J Ethnopharmacol.2016, 192:370-381
  • Biochem Systematics and Ecology2017, 11-18
  • PLoS One.2017, 12(3):e0173585
  • Semyung University2017, 149407
  • J Ethnopharmacol.2017, 197:157-164
  • The Japan Society for Analy. Chem.2017, 66(8):613-617
  • Sci Rep. 2018, 10590
  • Neuropharmacology.2018, 131:68-82
  • Chemistry of Natural Compounds2018, 204–206
  • Life Sci.2018, 209:498-506
  • RSC Adv.2018, 32621-32636
  • Wageningen University & Research2018, January 2018
  • J Cancer.2019, 10(23):5843-5851
  • Pharmacognosy Journal2019, 11(2): 369-373
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1126-1127:121743
  • BMC Complement Altern Med.2019, 19(1):339
  • Molecules.2019, 24(10):E1930
  • Food Chem.2019, 275:746-753
  • Int Immunopharmacol.2019, 71:361-371
  • Psychopharmacology (Berl).2020, 10.1007
  • J Mol Recognit.2020, 33(2):e2819
  • ...
  • 生物活性
    Description: Alpha-pinene inhibits the nuclear translocation of NF-kappa B induced by LPS in THP-1 cells, and this effect is partly due to the upregulation of I kappa B alpha expression. Alpha-pinene inhibits early root growth and causes oxidative damage in root tissue through enhanced generation of ROS, as indicated by increased lipid peroxidation, disruption of membrane integrity and elevated antioxidant enzyme levels.
    Targets: NF-kB | p65 | ROS
    In vitro:
    Acta Pharmacol Sin. 2004 Apr;25(4):480-4.
    Effect of alpha-pinene on nuclear translocation of NF-kappa B in THP-1 cells.[Pubmed: 15066217]

    METHODS AND RESULTS:
    To study the effects of Alpha-pinene on nuclear translocation of nuclear factor-kappa B (NF-kappa B) and the expression of the inhibitThe majority of FITC-labelled NF-kappa B/p65 was located in the nuclei being stimulated with LPS. Whereas, no such fluorescence was seen in the nuclei of the groups pretreated with Alpha-pinene or control cells. Alpha-pinene pretreatment decreased the NF-kappa B/p65 nuclear translocation in LPS-stimulated THP-1 cells, and this effect was dose-dependent, but there was no reaction in LPS-unstimulated THP-1 cells. Alpha-pinene pretreatment increased I kappa B alpha protein level in cytoplasm, compared with that in LPS-stimulated THP-1 cells.
    CONCLUSIONS:
    In a dose-related fashion, Alpha-pinene inhibits the nuclear translocation of NF-kappa B induced by LPS in THP-1 cells, and this effect is partly due to the upregulation of I kappa B alpha expression.or of NF-kappa B (I kappa B alpha) in human monocyte THP-1 cell line.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 7.3421 mL 36.7107 mL 73.4214 mL 146.8429 mL 183.5536 mL
    5 mM 1.4684 mL 7.3421 mL 14.6843 mL 29.3686 mL 36.7107 mL
    10 mM 0.7342 mL 3.6711 mL 7.3421 mL 14.6843 mL 18.3554 mL
    50 mM 0.1468 mL 0.7342 mL 1.4684 mL 2.9369 mL 3.6711 mL
    100 mM 0.0734 mL 0.3671 mL 0.7342 mL 1.4684 mL 1.8355 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    地芰普内酯; Loliolid CFN92750 5989-02-6 C11H16O3 = 196.2 5mg QQ客服:1413575084
    异地芰普内酯; Isololiolide CFN95106 38274-00-9 C11H16O3 = 196.2 5mg QQ客服:2159513211
    4-羟基-2,6,6-三甲基-1-环己烯羧酸; 4-Hydroxy-2,6,6-trimethyl-1-cyclohexenecarboxylic acid CFN97070 62218-55-7 C10H16O3 = 184.2 5mg QQ客服:2932563308
    地黄苦苷; Rehmapicroside CFN90760 104056-82-8 C16H26O8 = 346.4 5mg QQ客服:1413575084
    苦番红花素; Picrocrocin CFN91177 138-55-6 C16H26O7 = 330.4 5mg QQ客服:2159513211
    β-蒎烯; Beta-pinene CFN93287 18172-67-3 C10H16 = 136.2 20mg QQ客服:1148253675
    α-蒎烯; Alpha-pinene CFN93285 80-56-8 C10H16 = 136.2 20mg QQ客服:1148253675

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