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    1,3,6-三没食子酰葡萄糖

    1,3,6-Tri-O-galloylglucose

    1,3,6-三没食子酰葡萄糖
    产品编号 CFN95043
    CAS编号 18483-17-5
    分子式 = 分子量 C27H24O18 = 636.5
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The peels of Punica granatum L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    1,3,6-三没食子酰葡萄糖 CFN95043 18483-17-5 1mg QQ客服:2056216494
    1,3,6-三没食子酰葡萄糖 CFN95043 18483-17-5 5mg QQ客服:2056216494
    1,3,6-三没食子酰葡萄糖 CFN95043 18483-17-5 10mg QQ客服:2056216494
    1,3,6-三没食子酰葡萄糖 CFN95043 18483-17-5 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

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    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
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    IF=12.804(2019)

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  • Research on Crops.2017, 18(2)
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  • Molecules.2017, 22(11)
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  • Natural Product Communications2020, doi: 10.1177.
  • Institut Pasteur Korea2020, doi: 10.21203.
  • ...
  • 生物活性
    Description: 1,3,6-Tri-O-galloylglucose shows anti-inflammatory activity.
    Targets: Immunology & Inflammation related
    In vitro:
    Chinese Pharmaceutical Journal, 2015,50(19):1673-7.
    Study on the anti-inflammatory active constituents of Mangifera indica L. seed kernel.[Reference: WebLink]
    To study the anti-inflammatory active constituents of Mangifera indica L. seed kernel.
    METHODS AND RESULTS:
    The compounds were isolated by silica gel column chromatography, Sephadex LH-20 column chromatography and ODS column chromatography.Their structures were elucidated by spectral analyses and physicochemical properties. The anti-inflammatory activities of selected isolated compounds were evaluated as inhibitory activities against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cell lines by Griess reaction. Eight compounds were obtained from n-butanol fraction oi Mangifera indica L. seed kernel, whose structures were elucidated as 4-O-ethylgallic acid (1), gallic acid (2), citric acid(3), 1,2,3,4,6-penta-O-galloylglucose(4),1,3,6-Tri-O-galloylglucose(5), hyperoside(6), quercetin-3-O-rhamnopyranoside(7), and mangiferin(8). Compounds 1, 2 and 4-8 exhibited potent inhibitory effect on NO production in LPS-induced macrophages, especially compounds 6 and 8 showed the best inhibitory activity with IC50 values of 16.5 and 19.5 μmol·L-1, respectively.
    CONCLUSIONS:
    Compounds 1 and 3-8 were obtained from Mangifera indica L.seed kernel for the first time.Compounds 1, 2 and 4-8 are the anti-inflammatory active constituents oi Mangifera indica L.seed kernel.Compounds 6 and 8 are the most potent anti-inflammatory active constituents.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5711 mL 7.8555 mL 15.7109 mL 31.4218 mL 39.2773 mL
    5 mM 0.3142 mL 1.5711 mL 3.1422 mL 6.2844 mL 7.8555 mL
    10 mM 0.1571 mL 0.7855 mL 1.5711 mL 3.1422 mL 3.9277 mL
    50 mM 0.0314 mL 0.1571 mL 0.3142 mL 0.6284 mL 0.7855 mL
    100 mM 0.0157 mL 0.0786 mL 0.1571 mL 0.3142 mL 0.3928 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    1,2,3,4,6-五没食子酰葡萄糖; 1,2,3,4,6-O-Pentagalloylglucose CFN90192 14937-32-7 C41H32O26 = 940.68 20mg QQ客服:1457312923
    单宁酸; Tannic acid CFN90501 1401-55-4 C76H52O46 = 1701.2 20mg QQ客服:2932563308
    柯里拉京; Corilagin CFN90176 23094-69-1 C27H22O18 = 634.45 20mg QQ客服:2056216494
    诃子宁; Chebulanin CFN92294 166833-80-3 C27H24O19 = 652.5 5mg QQ客服:3257982914
    Thonningianin A; Thonningianin A CFN90633 271579-11-4 C42H34O21 = 874.7 10mg QQ客服:3257982914
    Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose; Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose CFN90881 205370-59-8 C42H32O21 = 872.7 10mg QQ客服:2159513211
    老鹳草素; Geraniin CFN90256 60976-49-0 C41H28O27 = 952.64 20mg QQ客服:3257982914
    诃子鞣酸; Chebulagic acid CFN92295 23094-71-5 C41H30O27 = 954.7 5mg QQ客服:2159513211
    诃子林鞣酸; Chebulinic acid CFN92296 18942-26-2 C41H32O27 = 956.7 10mg QQ客服:1413575084
    新诃黎勒鞣花酸甲酯; Methyl neochebulinate CFN95201 1236310-34-1 C42H36O28 = 988.7 5mg QQ客服:2932563308

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