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  • 芫花素-5-O-茜黄苷

    Yuankanin

    芫花素-5-O-茜黄苷
    产品编号 CFN95128
    CAS编号 77099-20-8
    分子式 = 分子量 C27H30O14 = 578.5
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Daphne genkwa
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    芫花素-5-O-茜黄苷 CFN95128 77099-20-8 1mg QQ客服:1148253675
    芫花素-5-O-茜黄苷 CFN95128 77099-20-8 5mg QQ客服:1148253675
    芫花素-5-O-茜黄苷 CFN95128 77099-20-8 10mg QQ客服:1148253675
    芫花素-5-O-茜黄苷 CFN95128 77099-20-8 20mg QQ客服:1148253675
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Leipzig (Germany)
  • Imperial College London (United Kingdom)
  • University of Zurich (Switzerland)
  • Aarhus University (Denmark)
  • Institute of Tropical Disease Universitas Airlangga (Indonesia)
  • Georgia Institute of Technology (USA)
  • Texas A&M University (USA)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • Weizmann Institute of Science (Israel)
  • University of East Anglia (United Kingdom)
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  • Korea Food Research Institute(KFRI) (Korea)
  • Kyushu University (Japan)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Chromatogr B Analyt Technol Biomed Life Sci. 2017, 1064:115-123
  • Russian J Bioorganic Chemistry 2021, 47:1411-1417.
  • Vojnosanit Pregl2016, 75(00):391-391
  • Acta Biochim Pol.2015, 62(2):253-8
  • The University of Manitoba2021, 35690.
  • Anal Biochem.2019, 569:10-15
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1113:1-13
  • Cell Metab.2020, S1550-4131(20)30002-4
  • Braz J Med Biol Res. 2016, 49(7)
  • Int J Mol Sci.2017, 18(5)
  • Saudi Pharm J2020, 10.1016
  • Front Aging Neurosci.2019, 11:230
  • Natural Product Communications2020, doi: 10.1177.
  • Acta Chromatographica2016, 29(3)
  • Phytomedicine.2021, 93:153789.
  • Biomed Sci Letters.2020, 26:319-326
  • Curr Res Virol Sci.2022, 3:100019.
  • PLoS One.2021, 16(9):e0257243.
  • Nutrients.2019, 12(1):E40
  • Sci Rep. 2017, 8207(7)
  • Current Traditional Medicine, 2021, 7:326-335(10).
  • Biochem Biophys Res Commun.2020, 527(4):889-895.
  • Molecules.2017, 22(2)
  • ...
  • 生物活性
    Description: Reference standards.
    In vitro:
    Phytochemistry. 2008 Jan;69(2):541-5.
    Flavones from Struthiola argentea with anthelmintic activity in vitro.[Pubmed: 17923139 ]
    Parasitic diseases caused by helminthes lead to significant health hazards to animals resulting in enormous economic impact. While a number of anthelmintics are currently available, all are encountering resistance and ones with a mode of action are needed.
    METHODS AND RESULTS:
    We report herein bioassay-guided isolation of three anthelmintic flavones 1-3, including the flavone, 5,6,2',5',6'-pentamethoxy-3',4'-methylenedioxyflavone (3) from the methanol extract of Struthiola argentea (Thymelaeaceae). The structure of 3 was elucidated by analysis of its 1D and 2D NMR and MS data. The two major flavones produced by this plant were also isolated and identified as yuankanin (4) and amentoflavone (5). A number of flavones related to the compounds isolated from S. argentea were acquired and tested to ascertain structure activity relationships. The isolation, structure, anthelmintic activity and structure activity relationships of the flavones are described.
    CONCLUSIONS:
    Compound 3 exhibited the most potent in vitro activity with 90% inhibition of larval motility at 3.1 microg/mL and compound 15 showed modest in vivo activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7286 mL 8.643 mL 17.2861 mL 34.5722 mL 43.2152 mL
    5 mM 0.3457 mL 1.7286 mL 3.4572 mL 6.9144 mL 8.643 mL
    10 mM 0.1729 mL 0.8643 mL 1.7286 mL 3.4572 mL 4.3215 mL
    50 mM 0.0346 mL 0.1729 mL 0.3457 mL 0.6914 mL 0.8643 mL
    100 mM 0.0173 mL 0.0864 mL 0.1729 mL 0.3457 mL 0.4322 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    5-羟基-7,8,2',5'-四甲氧基黄酮 5-O-葡萄糖苷; 5-Hydroxy-7,8,2',5'-tetramethoxyflavone 5-O-glucoside CFN97595 942626-75-7 C25H28O12 = 520.49 5mg QQ客服:1148253675
    木犀草苷; 木犀草素-7-O-葡萄糖苷; Luteolin-7-O-glucoside CFN98565 5373-11-5 C21H20O11 = 448.38 20mg QQ客服:1148253675
    木犀草素-7-O-葡萄糖醛酸苷; Luteolin-7-O-glucuronide CFN98512 29741-10-4 C21H18O12 = 462.36 20mg QQ客服:1148253675
    忍冬苷; Lonicerin CFN95055 25694-72-8 C27H30O15 = 594.5 10mg QQ客服:1413575084
    木犀草素 7-芸香糖苷; Luteolin 7-rutinoside CFN93556 20633-84-5 C27H30O15 = 594.52 10mg QQ客服:3257982914
    木犀草素 5-葡萄糖苷; Luteollin 5-glucoside CFN98568 20344-46-1 C21H20O11 = 448.38 5mg QQ客服:2932563308
    芫花叶苷; Yuanhuanin CFN95127 83133-14-6 C22H22O11 = 462.4 5mg QQ客服:1413575084
    芫花素-5-O-茜黄苷; Yuankanin CFN95128 77099-20-8 C27H30O14 = 578.5 5mg QQ客服:3257982914
    木犀草素-3'-葡萄糖醛酸苷; Luteolin-3-O-beta-D-glucuronide CFN93187 53527-42-7 C21H18O12 = 462.4 10 mg QQ客服:3257982914
    木犀草素-7-二葡萄糖苷酸; Luteolin 7-diglucuronide CFN70468 96400-45-2 C27H26O18 = 638.5 5mg QQ客服:2932563308

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