大豆皂苷Bd
Soyasaponin Bd
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| 大豆皂苷Bd |
CFN90775 |
135272-91-2 |
1mg |
QQ客服：2056216494 |
| 大豆皂苷Bd |
CFN90775 |
135272-91-2 |
5mg |
QQ客服：2056216494 |
| 大豆皂苷Bd |
CFN90775 |
135272-91-2 |
10mg |
QQ客服：2056216494 |
| 大豆皂苷Bd |
CFN90775 |
135272-91-2 |
20mg |
QQ客服：2056216494 |
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Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
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国外学术期刊发表的引用ChemFaces产品的部分文献
| Description: |
1. Soyasaponins has chemoprevention activities, it prevent H₂O₂-induced inhibition of gap junctional intercellular communication by scavenging reactive oxygen species in rat liver cells.
2. Soyasaponins can significantly decrease blood glucose, improve atherosclerotic index, and inhibit lipid peroxidation and platelet aggregation in diabetic rats, which may be useful in prevention and control of diabetes mellitus and diabetes-associated atherosclerosis.
3. Soyasaponins abundant in soybean have anti-inflammatory activities, low-dose SSs alleviated contact hypersensitivity (CHS) symptoms by attenuating inflammation and improving the intestinal microbiota composition, suggesting that dietary SSs may have beneficial effects on allergic contact dermatitis (ACD).
4. Dietary soyasaponin has inhibitory effects on 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice.
|
| Targets: |
ROS | Immunology & Inflammation related |
| In vitro: |
| J Enzyme Inhib Med Chem . 2019 Dec;34(1):350-360. | | Soyasaponins from Zolfino bean as aldose reductase differential inhibitors[Pubmed: 30734590] | | Abstract
Seven triterpenoid saponins were identified in methanolic extracts of seeds of the Zolfino bean landrace (Phaseolus vulgaris L.) by HPLC fractionation, revealing their ability to inhibit highly purified human recombinant aldose reductase (hAKR1B1). Six of these compounds were associated by MS analysis with the following saponins already reported in different Phaseolus vulgaris varieties: soyasaponin Ba (V), soyasaponin Bb, soyasaponin Bd (sandosaponin A), soyasaponin αg, 3-O-[R-l-rhamnopyranosyl(1 → 2)-α-d-glucopyranosyl(1 → 2)-α-d-glucuronopyranosyl]olean-12-en-22-oxo-3α,-24-diol, and soyasaponin βg. The inhibitory activity of the collected fractions containing the above compounds was tested for hAKR1B1-dependent reduction of both l-idose and 4-hydroxynonenal, revealing that some are able to differentially inhibit the enzyme. The present work also highlights the difficulties in the search for aldose reductase differential inhibitors (ARDIs) in mixtures due to the masking effect on ARDIs exerted by the presence of conventional aldose reductase inhibitors. The possibility of differential inhibition generated by a different inhibitory model of action of molecules on different substrates undergoing transformation is also discussed.
Keywords: Saponins; Zolfino bean; aldose reductase; differential inhibitors. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.0448 mL |
5.2241 mL |
10.4482 mL |
20.8965 mL |
26.1206 mL |
| 5 mM |
0.209 mL |
1.0448 mL |
2.0896 mL |
4.1793 mL |
5.2241 mL |
| 10 mM |
0.1045 mL |
0.5224 mL |
1.0448 mL |
2.0896 mL |
2.6121 mL |
| 50 mM |
0.0209 mL |
0.1045 mL |
0.209 mL |
0.4179 mL |
0.5224 mL |
| 100 mM |
0.0104 mL |
0.0522 mL |
0.1045 mL |
0.209 mL |
0.2612 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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