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  • 常春藤皂甙元-3-O-(2-O-乙酰基-α-L-吡喃阿拉伯糖甙)

    Hederagenin 3-O-(2-O-acetyl-alpha-L-arabinopyranoside)

    常春藤皂甙元-3-O-(2-O-乙酰基-α-L-吡喃阿拉伯糖甙)
    产品编号 CFN95355
    CAS编号 87562-05-8
    分子式 = 分子量 C37H58O9 = 646.9
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The herbs of Caulophyllum robustum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    常春藤皂甙元-3-O-(2-O-乙酰基-α-L-吡喃阿拉伯糖甙) CFN95355 87562-05-8 1mg QQ客服:3257982914
    常春藤皂甙元-3-O-(2-O-乙酰基-α-L-吡喃阿拉伯糖甙) CFN95355 87562-05-8 5mg QQ客服:3257982914
    常春藤皂甙元-3-O-(2-O-乙酰基-α-L-吡喃阿拉伯糖甙) CFN95355 87562-05-8 10mg QQ客服:3257982914
    常春藤皂甙元-3-O-(2-O-乙酰基-α-L-吡喃阿拉伯糖甙) CFN95355 87562-05-8 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of British Columbia (Canada)
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  • University of Bonn (Germany)
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  • Universiti Malaysia Pahang (Malaysia)
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  • Martin Luther University of Halle-Wittenberg (Germany)
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  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Antibiotics.2022, 11(4), 510.
  • J. Traditional Thai Medical Res. 2022,8(1):1-14.
  • Vietnam Journal of Science2022,64(2):69-75.
  • Nutr Cancer.2022, 1-13.
  • J Microbiol Biotechnol.2022, 32(2):141-148.
  • Food Research International2020, 108987
  • Pharmaceuticals (Basel).2020, 13(10):302.
  • Compounds.2023, 3(1), 169-179.
  • J Nat Med.2020, 74(3):550-560.
  • Sci Rep.2021, 11(1):11936.
  • Plant Cell, Tissue and Organ Culture (PCTOC)2020, 143, 45-60(2020)
  • Pharmaceutics.2021, 13(7):1028.
  • Research Square2020, doi: 10.21203.
  • Applied Biological Chem. 2020, 26(63).
  • BMC Plant Biol.2020, 20(1):214.
  • International J of Green Pharmacy2019, 13(3)
  • Chem Biol Interact.2016, 258:59-68
  • Appl. Sci. 2021, 11(17),7829
  • JPC-Journal of Planar Chromatography2023, 36:179-190
  • Biochem Biophys Res Commun.2021, 534:802-807.
  • Agronomy2023, 13(6), 1435.
  • Front Pharmacol.2021, 12:770667.
  • TCI CO.2019, US20190151257A1
  • ...
  • 生物活性
    Description: Hederagenin 3-O-(2-O-acetyl-α-L-arabinopyranoside) significantly increased alkaline phosphatase (ALP) activity and the level of protein expression of bone sialoprotein (BSP) and osteocalcin (OC) .
    In vitro:
    Biosci Biotechnol Biochem . 2011;75(1):13-19.
    Effects of the dichloromethane fraction of Dipsaci Radix on the osteoblastic differentiation of human alveolar bone marrow-derived mesenchymal stem cells[Pubmed: 21228489]
    Dipsaci Radix is the dried root of Dipsacus asper Wall. It has been used in Korean herbal medicine to treat bone fractures. In this study, we examined the effect of the dichloromethane fraction of Dipsaci Radix (DR(DM)) on the osteoblastic differentiation of human alveolar bone marrow-derived MSCs (ABM-MSCs). The ABM-MSCs were isolated from healthy subjects and cultured in vitro, followed by phenotypic characterization. They showed a fibroblast-like morphology and expressed CD29, CD44, CD73, and CD105, but not CD34. Calcified nodules were generated in response to both dexamethasone (DEX) and DR(DM). There was a significant increase in the alkaline phosphatase (ALP) activity and protein expression of bone sialoprotein (BSP) and osteocalcin (OC) in response to DEX and DR(DM) as compared to control. These results provide evidence for the osteogenic potential of cultured ABM-MSCs in response to DR(DM). Also, an active single compound was additionally isolated from DR(DM). The single compound (hederagenin 3-O-(2-O-acetyl)-α-L-arabinopyranoside) also significantly increased ALP activity and the level of protein expression of BSP and OC. These results highlight the possible clinical applications of DR(DM) and hederagenin 3-O-(2-O-acetyl)-α-L-arabinopyranoside in bone regeneration.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5458 mL 7.7292 mL 15.4583 mL 30.9167 mL 38.6458 mL
    5 mM 0.3092 mL 1.5458 mL 3.0917 mL 6.1833 mL 7.7292 mL
    10 mM 0.1546 mL 0.7729 mL 1.5458 mL 3.0917 mL 3.8646 mL
    50 mM 0.0309 mL 0.1546 mL 0.3092 mL 0.6183 mL 0.7729 mL
    100 mM 0.0155 mL 0.0773 mL 0.1546 mL 0.3092 mL 0.3865 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    川续断皂苷IX; Dipsacussaponin C CFN95353 152406-43-4 C64H104O30 = 1353.5 5mg QQ客服:2056216494
    白头翁皂苷E2; Pulchinenoside E2 CFN80362 244202-36-6 C53H86O21 = 1059.24 5mg QQ客服:2056216494
    Dipsacobioside; Dipsacobioside CFN94827 123350-57-2 C41H66O12 = 750.96 5mg QQ客服:2159513211
    丝石竹皂苷元; Gypsogenin CFN91485 639-14-5 C30H46O4 = 470.7 5mg QQ客服:1457312923
    丝石竹皂苷元-3-O-β-D-葡萄糖醛酸甲酯; Methyl gypsogenin 3-O-beta-D-glucuronopyranoside CFN90727 96553-02-5 C37H56O10 = 660.9 20mg QQ客服:2159513211
    贝萼皂苷元 3-O-beta-D-吡喃葡萄糖苷; Bayogenin 3-O-beta-D-glucopyranoside CFN90996 104513-86-2 C36H58O10 = 650.84 5mg QQ客服:215959384
    细叶远志皂苷; Tenuifolin CFN98157 20183-47-5 C36H56O12 = 680.37 20mg QQ客服:1413575084
    红背银莲花皂甙20; Raddeanoside 20 CFN90659 335354-79-5 C47H76O17 = 913.1 5mg QQ客服:215959384
    刺五加皂苷B; Ciwujianoside B CFN99983 114902-16-8 C58H92O25 = 1189.35 20mg QQ客服:3257982914
    Eupteleasaponin I; Eupteleasaponin I CFN90959 290809-29-9 C52H82O21 = 1043.21 5mg QQ客服:215959384

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