DL-α-生育酚乙酸酯

DL-alpha-Tocopherylacetate

	产品编号	CFN90785
	CAS编号	7695-91-2
	分子式 = 分子量	C₃₁H₅₂O₃ = 472.74
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Phenols
	植物来源	The herbs of Isodon adenantha
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
DL-α-生育酚乙酸酯	CFN90785	7695-91-2	1mg	QQ客服：215959384
DL-α-生育酚乙酸酯	CFN90785	7695-91-2	5mg	QQ客服：215959384
DL-α-生育酚乙酸酯	CFN90785	7695-91-2	10mg	QQ客服：215959384
DL-α-生育酚乙酸酯	CFN90785	7695-91-2	20mg	QQ客服：215959384

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

University of Hawaii Cancer Center (USA)

University of Helsinki (Finland)

Johannes Gutenberg University Mainz (JGU) (Germany)

Complutense University of Madrid (Spain)

Pennsylvania State University (USA)

Donald Danforth Plant Science Center (USA)

Instytut Nawozów Sztucznych w Pu?awach (Poland)

Kyoto University (Japan)

University of Beira Interior (Portugal)

Utrecht University (Netherlands)

John Innes Centre (United Kingdom)

Siksha O Anusandhan University (India)

Monash University Malaysia (Malaysia)

University of Parma (Italy)

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Description:

Dl-alpha-tocopheryl acetate is a dietary supplement. Dl-alpha-Tocopherylacetate shows anti-inflammatory and analgesic activity, it acts synergistically with aspirin towards reducing inflammation and pain as well as the former reduced the gastric ulcerogenic potential of the latter. Dl-alpha-Tocopherylacetate induces hypocoagulability and platelet hypoaggregability in rats.

Targets:

Immunology & Inflammation related

In vivo:

J Agric Food Chem. 2006 Jan 25;54(2):568-73.

Incorporation of alpha-tocopherol and linoleic acid in fresh lambs by feeding chemically treated dietary supplements containing dl-alpha-tocopheryl acetate and sunflower oil.[Pubmed: 16417322 ]

The effects of feeding chemically treated dietary supplements (CTDS) containing sunflower oil and dl-alpha-tocopheryl acetate (TA) on alpha-tocopherol content and fatty acid profile in edible tissues of lambs were estimated.
METHODS AND RESULTS:
Compared with lambs fed control diet (CD), lambs fed CD plus 250 IU of either TA or CTDS increased serum alpha-tocopherol. The CTDS-fed lambs further increased serum alpha-tocopherol by 29% over those fed CD plus 250 IU of TA. Lambs supplemented with TA or CTDS increased alpha-tocopherol in muscle and adipose tissues as compared with lambs fed CD. The CTDS-fed lambs had higher levels of alpha-tocopherol in gluteus medius (7.55 vs 6.05 mug/g), psoas major (7.43 vs 6.02 mug/g), and subcutaneous fat (12.6 vs 9.98 mug/g) compared with the TA-fed lambs.
CONCLUSIONS:
Feeding lambs CTDS also substantially increased levels of linoleic acid in the adipose tissues while decreasing the content of palmitic and oleic acids.

Int J Vitam Nutr Res. 1987;57(4):375-9.

dl-alpha-Tocopheryl acetate induces hypocoagulability and platelet hypoaggregability in rats.[Pubmed: 3440712]

METHODS AND RESULTS:
Rats receiving daily IP injections of DL-alpha-Tocopherylacetate (50 mg/kg) for 4 days showed levels of plasma alpha-tocopherol slightly increased and normal platelet count but platelet aggregation (induced by ADP or adrenaline) was significantly decreased when compared with the control animals. In addition, both platelet-rich plasma and platelet-poor plasma-thromboelastograms from treated rats showed thromboplastine-formation times significantly higher than those from control animals. Serum biochemical parameters showed several minor modifications in treated rats with respect the control ones.
CONCLUSIONS:
It suggests that vitamin E could be considered as a possible useful tool for the therapy of several hyperaggregable or hypercoagulable states.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
帕比司他; Panobinostat (LBH589)	CFN60033	404950-80-7	C₂₁H₂₃N₃O₂ = 349.43	5mg	QQ客服：2056216494
Chamaemeloside; Chamaemeloside	CFN70289	173356-77-9	C₂₇H₂₈O₁₄ = 576.5	5mg	QQ客服：1413575084
3-Keto-齐墩果酸-28-甲酯; 3-Oxo-olean-12-en-28-oic acid methyl ester	CFN91814	1721-58-0	C₃₁H₄₈O₃ = 468.7	5mg	QQ客服：3257982914
高三尖杉酯碱; Homoharringtonine	CFN98110	26833-87-4	C₂₉H₃₉NO₉ = 545.61	20mg	QQ客服：3257982914

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.1153 mL	10.5766 mL	21.1533 mL	42.3066 mL	52.8832 mL
5 mM	0.4231 mL	2.1153 mL	4.2307 mL	8.4613 mL	10.5766 mL
10 mM	0.2115 mL	1.0577 mL	2.1153 mL	4.2307 mL	5.2883 mL
50 mM	0.0423 mL	0.2115 mL	0.4231 mL	0.8461 mL	1.0577 mL
100 mM	0.0212 mL	0.1058 mL	0.2115 mL	0.4231 mL	0.5288 mL