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  • 郁金二酮

    Curcumadione

    郁金二酮
    产品编号 CFN92617
    CAS编号 116425-36-6
    分子式 = 分子量 C15H22O2 = 234.3
    产品纯度 >=98%
    物理属性 Cryst.
    化合物类型 Sesquiterpenoids
    植物来源 The rhizomes of Curcuma wenyujin
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    郁金二酮 CFN92617 116425-36-6 1mg QQ客服:2056216494
    郁金二酮 CFN92617 116425-36-6 5mg QQ客服:2056216494
    郁金二酮 CFN92617 116425-36-6 10mg QQ客服:2056216494
    郁金二酮 CFN92617 116425-36-6 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Res Rep Urol.2022, 14:313-326.
  • Tokyo Pharmaceutical University2020, 500001431953.
  • Biochem Biophys Res Commun.2018, 495(1):1271-1277
  • Food Chem Toxicol.2023, 176:113785.
  • Vojnosanit Pregl2016, 75(00):391-391
  • Mol Plant Pathol.2022, 10.1111:mpp.13280.
  • Microchemical Journal2018, 137:168-173
  • Molecules.2022, 27(21):7643.
  • Biomolecules.2022, 12(12):1754.
  • Molecules.2018, 23(3):E615
  • J Agric Food Chem.2017, 65(13):2670-2676
  • Sustainable Chemistry & Pharmacy2022, 30:100883.
  • Applied Biological Chemistry2022, 71:s13765-022-00743-5.
  • Antibiotics.2022, 11(4), 510.
  • Analytical Letters.2020, doi 10.1008
  • Foods. 2022, 11(23):3905.
  • J of Advanced Scientific R.2020, 11(3), p109-120.
  • LWT2020, 110397
  • J Biochem Mol Toxicol.2021, 35(5):e22731.
  • J.Pharm. & Biome. Anal.2023, 2: 100018.
  • Nutrients.2022, 14(16):3393.
  • J Biochem Mol Toxicol.2022, e23211.
  • Anal Bioanal Chem.2018, 410(5):1561-1569
  • ...
  • 生物活性
    Description: Curcumadione shows certain acetylcholinesterase inhibitory activity.
    Targets: AChR
    In vitro:
    Journal of Shandong University, 2013,48(7):20-3.
    Chemical constituents of Curcuma xanthorrhiza Roxb. and their acetylcholinesterase inhibitory activity[Reference: WebLink]

    METHODS AND RESULTS:
    Chemical constituents from Curcuma xanthorrhiza Roxb. (Zingiberaceae) rhizome were isolated and purified by column chromatography (silica gel, RP silica gel MPLC, HPLC) and their structures were elucidated on the basis of spectral analyses. Six compounds were identified by MS and NMR spectroscopy as zederone(I), beta-sitosterol(II), Guai-1(10),3,5,7(11),8-pentaen-2-on-11,8-olide(III), Curcumadione(IV), Curcumenone (V), Cuparenol (VI). Compound III and VI were isolated for the first time from the plants of Zingiberaceae, and compound IV and V were isolated from Curcuma xanthorrhiza Roxb. for the first time. Meanwhile, the acetylcholinesterase inhibitory activity of the isolated compounds was evaluated.
    CONCLUSIONS:
    Compounds IV and VI showed certain inhibitory activity, the minimum inhibitory quantity of IV on TLC bioautography test was 95ug.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.268 mL 21.3402 mL 42.6803 mL 85.3606 mL 106.7008 mL
    5 mM 0.8536 mL 4.268 mL 8.5361 mL 17.0721 mL 21.3402 mL
    10 mM 0.4268 mL 2.134 mL 4.268 mL 8.5361 mL 10.6701 mL
    50 mM 0.0854 mL 0.4268 mL 0.8536 mL 1.7072 mL 2.134 mL
    100 mM 0.0427 mL 0.2134 mL 0.4268 mL 0.8536 mL 1.067 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    叶黄制菌素; Xanthatin CFN98315 26791-73-1 C15H18O3 = 246.3 5mg QQ客服:1413575084
    8-Epixanthatin; 8-Epixanthatin CFN89507 30890-35-8 C15H18O3 = 246.30 5mg QQ客服:215959384
    6alpha-Hydroxytomentosin; 6alpha-Hydroxytomentosin CFN89001 1232676-22-0 C15H20O4 = 264.32 5mg QQ客服:3257982914
    黄质宁; Xanthinin CFN99644 153483-31-9 C17H22O5 = 306.4 5mg QQ客服:215959384
    旋覆花内酯; Britannilactone CFN92601 33620-72-3 C15H22O4 = 266.3 20mg QQ客服:1413575084
    1-O-乙酰旋覆花内酯; 1-O-Acetyl britannilactone CFN90219 681457-46-5 C17H24O5 = 266.34 20mg QQ客服:3257982914
    1,6-O,O-二乙酰大花旋覆花内酯; 1,6-O,O-Diacetylbritannilactone CFN89518 1286694-67-4 C19H26O6 = 350.40 5mg QQ客服:3257982914
    1-O-乙酰-6β-O-异丁酰旋覆花内酯; 1-O-Acetyl-6beta-O-Isobutyrylbritannilactone CFN92598 1087072-50-1 C21H30O6 = 378.5 5mg QQ客服:1413575084
    1-O-乙酰基-6alpha-O-(2-甲基丁酰)大花旋覆花内酯; 1-O-Acetyl-6alpha-O-(2-methylbutyryl)britannilactone CFN89470 1932687-71-2 C22H32O6 = 392.48 5mg QQ客服:2056216494
    二大花旋覆花内酯 B; Dibritannilactone B CFN89501 1829580-18-8 C34H46O9 = 598.72 5mg QQ客服:215959384

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