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  • 咖啡酸4-O-葡糖苷酸

    Caffeic acid 4-O-glucuronide

    咖啡酸4-O-葡糖苷酸
    产品编号 CFN95382
    CAS编号 1093679-71-0
    分子式 = 分子量 C15H16O10 = 356.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    咖啡酸4-O-葡糖苷酸 CFN95382 1093679-71-0 1mg QQ客服:2932563308
    咖啡酸4-O-葡糖苷酸 CFN95382 1093679-71-0 5mg QQ客服:2932563308
    咖啡酸4-O-葡糖苷酸 CFN95382 1093679-71-0 10mg QQ客服:2932563308
    咖啡酸4-O-葡糖苷酸 CFN95382 1093679-71-0 20mg QQ客服:2932563308
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • National Cancer Institute (USA)
  • University of Stirling (United Kingdom)
  • Universiti Sains Malaysia (Malaysia)
  • Seoul National University of Science and Technology (Korea)
  • Universidade Federal de Santa Catarina (Brazil)
  • Aarhus University (Denmark)
  • Universiti Putra Malaysia(UPM) (Malaysia)
  • Heinrich-Heine-University Düsseldorf (Germany)
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • Semmelweis Unicersity (Hungary)
  • Monash University Sunway Campus (Malaysia)
  • Monash University (Australia)
  • Nanjing University of Chinese Medicine (China)
  • Nicolaus Copernicus Uniwersity (Poland)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Proc Natl Acad Sci USA.2016, 113(30):E4407-1
  • J Ethnopharmacol.2019, 244:112074
  • Korean Journal of Pharmacognosy2018, 49(4):349-361
  • Asian J of Pharmaceutical&Clinical 2018, 11(2)
  • Journal of Apiculture2019, 34(2):131-136
  • Int J Mol Sci.2021, 22(10):5181.
  • Asian Journal of Chemistry2014, 26(8):2425
  • Sci Rep.2017, 7:40345
  • Universidade Estadual Paulista2017, 42785
  • Food and Chemical Toxicology2020, 111221
  • Antioxidants (Basel).2021, 10(8):1300.
  • Enzyme Microb Technol.2022, 153:109941.
  • Phytochemistry2018, 15:83-92
  • Front Pharmacol.2018, 9:236
  • Exp Parasitol.2017, 183:160-166
  • Preprints2022, 2022030063.
  • Biomed Pharmacother.2021, 144:112300.
  • Antioxidants (Basel).2019, 8(8):E307
  • J Nat Med.2022, 76(1):59-67.
  • Biomed Pharmacother.2022, 145:112474.
  • Ind Crops Prod.2014, 62:173-178
  • Mie University2019, 10076.
  • Plants (Basel).2021, 10(6):1192.
  • ...
  • 生物活性
    In vivo:
    Pharmaceutics . 2018 Sep 2;10(3):143.
    Simultaneous Determination of Chlorogenic Acid Isomers and Metabolites in Rat Plasma Using LC-MS/MS and Its Application to A Pharmacokinetic Study Following Oral Administration of Stauntonia Hexaphylla Leaf Extract (YRA-1909) to Rats[Pubmed: 30200538]
    Stauntonia hexaphylla leaf extract (YRA-1909), which is widely used for the antirheumatic properties, has been under phase 2 clinical trials in patients with rheumatoid arthritis since April 2017. Liquid chromatography-tandem mass spectrometric method while using liquid⁻liquid extraction with ethyl acetate was validated for the simultaneous determination of the major active components of YRA-1909, including chlorogenic acid (CGA), neochlorogenic acid (NCGA), cryptochlorogenic acid (CCGA), and their metabolites (i.e., caffeic acid (CA), caffeic acid 3-O-glucuronide (CA-3-G), caffeic acid 4-O-glucuronide (CA-4-G), and ferulic acid (FA)) in rat plasma and applied to a pharmacokinetic study of YRA-1909 in rats. Seven analytes were separated on Halo C18 while using gradient elution of formic acid and methanol, and then quantified in selected reaction monitoring mode whle using negative electrospray ionization. Following oral administration of YRA-1909 at doses of 25, 50, and 100 mg/kg to male Sprague-Dawley rats, CGA, NCGA, and CCGA were rapidly absorbed and metabolized to CA, CA-3-G, and CA-4-G. The area under the plasma concentration-time curve (AUClast) of CGA, NCGA, CCGA, and three metabolites linearly increased as the YRA-1909 dose increased. Other pharmacokinetic parameters were comparable among three doses studied. AUClast values for CA, CA-3-G, and CA-4-G exceeded those for CGA, NCGA, and CCGA.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8066 mL 14.0331 mL 28.0662 mL 56.1325 mL 70.1656 mL
    5 mM 0.5613 mL 2.8066 mL 5.6132 mL 11.2265 mL 14.0331 mL
    10 mM 0.2807 mL 1.4033 mL 2.8066 mL 5.6132 mL 7.0166 mL
    50 mM 0.0561 mL 0.2807 mL 0.5613 mL 1.1226 mL 1.4033 mL
    100 mM 0.0281 mL 0.1403 mL 0.2807 mL 0.5613 mL 0.7017 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    9-O-阿魏酰基-5,5'-二甲氧基落叶松树脂醇; 9-O-Feruloyl-5,5'-dimethoxylariciresinol CFN99700 166322-14-1 C32H36O11 = 596.6 5mg QQ客服:2159513211
    Corylifol A; Corylifol A CFN92226 775351-88-7 C25H26O4 = 390.5 20mg QQ客服:2159513211
    Luminespib (NVP-AUY922); Luminespib (NVP-AUY922) CFN60199 747412-49-3 C26H31N3O5 = 465.54 5mg QQ客服:3257982914
    Oxyphyllenone A; Oxyphyllenone A CFN96801 363610-34-8 C12H18O3 = 210.27 5mg QQ客服:3257982914

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