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  • 中药标准品生产商,产品定制服务
  • 鸦胆亭醇B

    Bruceantinol B

    鸦胆亭醇B
    产品编号 CFN95216
    CAS编号 1822332-33-1
    分子式 = 分子量 C27H34O12 = 550.6
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Diterpenoids
    植物来源 The fruits of Brucea javanica
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    鸦胆亭醇B CFN95216 1822332-33-1 1mg QQ客服:1413575084
    鸦胆亭醇B CFN95216 1822332-33-1 5mg QQ客服:1413575084
    鸦胆亭醇B CFN95216 1822332-33-1 10mg QQ客服:1413575084
    鸦胆亭醇B CFN95216 1822332-33-1 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Otago (New Zealand)
  • Biotech R&D Institute (USA)
  • University of Bonn (Germany)
  • The Vancouver Prostate Centre (VPC) (Canada)
  • University of Bordeaux (France)
  • Medical University of Gdansk (Poland)
  • Wroclaw Medical University (Poland)
  • Korea Institute of Oriental Medicine (Korea)
  • Massachusetts General Hospital (USA)
  • Universitas islam negeri Jakarta (Indonesia)
  • University of Fribourg (Switzerland)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Johannes Gutenberg University Mainz (JGU) (Germany)
  • Chinese University of Hong Kong (China)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Chem Biol Interact.2019, 298:1-7
  • Int J Mol Sci.2019, 20(21):E5488
  • J Agric Food Chem.2015, 63(44):9869-78
  • Molecules.2022, 27(7):2360.
  • Molecules.2017, 22(6)
  • Antioxidants (Basel).2021, 10(8):1300.
  • Phytomedicine.2022, 99:153997.
  • Int J Biol Macromol.2019, 126:653-661
  • Food Funct.2022, 13(14):7638-7649.
  • RSC Adv.2018, 32621-32636
  • Phytomedicine.2022, 96:153877.
  • Life Sci.2021, 286:120019.
  • J Sci Food Agric.2022, 102(4):1628-1639
  • Analytical sci. & Tech2016, 186-193
  • J Chem Inf Model.2021, 61(11):5708-5718.
  • Crystals2020, 10(3), 206.
  • FEMS Microbiol Lett.2017, 364(11)
  • Naunyn Schmiedebergs Arch Pharmacol.2017, 390(10):1073-1083
  • J Adv Res.2019, 17:85-94
  • Front Cell Infect Microbiol.2018, 8:292
  • Legume Science2021, 3(4): e101.
  • Processes2021, 9(1), 153;
  • Int J Mol Sci.2020, 21(6):2190.
  • ...
  • 生物活性
    Description: Reference standards.
    In vitro:
    J Nat Prod. 2007 Oct;70(10):1654-7.
    Screening of Indonesian medicinal plant extracts for antibabesial activity and isolation of new quassinoids from Brucea javanica.[Pubmed: 17896817 ]
    Boiled extracts derived from 28 Indonesian medicinal plants were screened for their antibabesial activity against Babesia gibsoni in vitro.
    METHODS AND RESULTS:
    Of these extracts, the fruit of Brucea javanica was the most active in inhibiting parasite growth at a concentration of 10 microg/mL. Bioassay-guided fractionation of the fruit extract of Br. javanica led to the isolation of two new quassinoids, bruceantinol B and bruceine J, and the structures of these compounds were elucidated on the basis of their spectroscopic data and by chemical transformation to known compounds. In addition, the known quassinoids bruceines A-D, bruceantinol, and yadanziolide A were isolated.
    CONCLUSIONS:
    Antibabesial activities were also examined in vitro, and bruceine A and bruceantinol were shown to be more potent than diminazene aceturate, a drug (IC50 = 103 ng/mL) used clinically against B. gibsoni, with IC50 values of 4 and 12 ng/mL, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8162 mL 9.081 mL 18.162 mL 36.324 mL 45.405 mL
    5 mM 0.3632 mL 1.8162 mL 3.6324 mL 7.2648 mL 9.081 mL
    10 mM 0.1816 mL 0.9081 mL 1.8162 mL 3.6324 mL 4.5405 mL
    50 mM 0.0363 mL 0.1816 mL 0.3632 mL 0.7265 mL 0.9081 mL
    100 mM 0.0182 mL 0.0908 mL 0.1816 mL 0.3632 mL 0.4541 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    13,18-二氢乐园树酮; 13,18-Dehydroglaucarubinone CFN92980 68703-94-6 C25H32O10 = 492.52 5mg QQ客服:2932563308
    (+)-乐园树酮; (+)-Glaucarubinone CFN92979 1259-86-5 C25H34O10 = 494.53 5mg QQ客服:2932563308
    鸦胆子素B; Bruceine B CFN89335 25514-29-8 C23H28O11 = 480.46 5mg QQ客服:215959384
    鸦胆子素C; Bruceine C CFN91974 25514-30-1 C28H36O12 = 564.58 5mg QQ客服:1413575084
    鸦胆醇; Bruceantinol CFN89336 53729-52-5 C30H38O13 = 606.62 5mg QQ客服:2932563308
    鸦胆亭醇B; Bruceantinol B CFN95216 1822332-33-1 C27H34O12 = 550.6 5mg QQ客服:2932563308
    鸦胆亭醇; Bruceantinol A CFN91971 948038-36-6 C29H36O13 = 592.59 5mg QQ客服:2159513211
    鸦胆子素J; Bruceine J CFN91973 948038-38-8 C25H32O11 = 508.51 5mg QQ客服:215959384
    鸦胆子素A; Bruceine A CFN89338 25514-31-2 C26H34O11 = 522.54 5mg QQ客服:2159513211
    鸦胆子苦醇; Brusatol CFN93119 14907-98-3 C26H32O11 = 520.53 20mg QQ客服:1148253675

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