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  • Annphenone

    Annphenone

    Annphenone
    产品编号 CFN95426
    CAS编号 61775-18-6
    分子式 = 分子量 C15H20O9 = 344.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The herbs of Oxyria sinensis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Annphenone CFN95426 61775-18-6 1mg QQ客服:3257982914
    Annphenone CFN95426 61775-18-6 5mg QQ客服:3257982914
    Annphenone CFN95426 61775-18-6 10mg QQ客服:3257982914
    Annphenone CFN95426 61775-18-6 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Technical University of Denmark (Denmark)
  • University of Illinois at Chicago (USA)
  • University of Pretoria (South Africa)
  • University of Maryland (USA)
  • University of Fribourg (Switzerland)
  • Massachusetts General Hospital (USA)
  • Pennsylvania State University (USA)
  • University of Malaya (Malaysia)
  • Seoul National University of Science and Technology (Korea)
  • University of Perugia (Italy)
  • Universite Libre de Bruxelles (Belgium)
  • Macau University of Science and Technology (China)
  • Utah State University (USA)
  • Celltrion Chemical Research Institute (Korea)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Environ Toxicol.2020, doi: 10.1002
  • Pharmaceuticals (Basel).2021, 14(7):633.
  • J Agric Food Chem.2020, 68(51):15164-15175
  • J Agric Food Chem.2018, 66(1):351-358
  • Biol Pharm Bull.2018, 41(1):65-72
  • Mol Immunol. 2016, 78:121-132
  • Int J Mol Sci.2020, 21(19):7209.
  • Curr Res Virol Sci.2022, 3:100019.
  • Food Research2021, 5(1):65-71
  • Arch Biochem Biophys.2018, 644:93-99
  • Appl. Sci. 2021, 11(23),11099.
  • Environ Toxicol Pharmacol.2019, 66:109-115
  • Fitoterapia.2022, 157:105130.
  • Molecules.2017, 22(11)
  • Molecules. 2013, 18(7):7376-88
  • J Agric Food Chem.2020, 68(43):12164-12172.
  • J Clin Med.2019, 8(10):E1664
  • Anticancer Res.2018, 38(4):2127-2135
  • BMB Rep.2020, 53(4):218-222.
  • Anat Rec (Hoboken).2021, 304(2):323-332.
  • Exp Neurobiol.2018, 27(3):200-209
  • Vietnam J. Chemistry2022, 60(2):211-222
  • Journal of Ginseng Research2021, 3 June.
  • ...
  • 生物活性
    Description: Annphenone exhibits antioxidant properties by inhibiting ROS generation and thus protecting cells from H2O2-induced cell damage.
    In vitro:
    Cell Biol Int. 2008 Sep;32(9):1099-1107.
    Cytoprotective activity of annphenone against oxidative stress-induced apoptosis in V79-4 lung fibroblast cells[Pubmed: 18550394]
    We have elucidated the cytoprotective effect of annphenone (2,4-dihyroxy-6-methoxy-acetophenone 4-O-beta-D-glucopyranoside) against oxidative stress-induced apoptosis. Annphenone scavenged intracellular reactive oxygen species (ROS) and increased antioxidant enzyme activities. It thereby prevented lipid peroxidation and DNA damage, which was demonstrated by the inhibition of the formation of thiobarbituric acid reactive substance (TBARS), inhibition of the comet tail and decreased phospho-H2A.X expression. Annphenone protected Chinese hamster lung fibroblast (V79-4) cells from cell death via the inhibition of apoptosis induced by hydrogen peroxide (H2O2), as shown by decreased apoptotic nuclear fragmentation, decreased sub-G1 cell population and inhibited mitochondrial membrane potential (Deltapsi) loss. Taken together, these findings suggest that annphenone exhibits antioxidant properties by inhibiting ROS generation and thus protecting cells from H2O2-induced cell damage.
    Zhongguo Zhong Yao Za Zhi . 2021 Mar;46(5):1160-1167.
    [Research on chemical constituents from Artemisia annua Ⅰ][Pubmed: 33787111]
    Chemical constituents were isolated and purified from the water extract of Artemisia annua by column chromatography of HP-20 macroporous resin, silica gel, ODS, Sephadex LH-20, HW-40, and semi-preparative RP-HPLC. Their structures were elucidated by physicochemical properties and spectral analyses. As a result, Fifteen compounds were isolated and identified as vitexnegheteroin M(1), sibricose A5(2), securoside A(3), citrusin D(4), annphenone(5), E-melilotoside(6), esculetin(7), scopoletin-7-O-β-D-glucoside(8), eleutheroside B_1(9), chrysosplenol D(10), patuletin-3-O-β-D-glucopyranoside(11), quercetin-7-O-β-D-glucoside(12), rutin(13), apigenin 6,8-di-C-β-D-glucopyranoside(14), isoschaftoside(15), among them, compounds 1-4 were identified from Artemisia for the first time. Additionally, the isolates were evaluated for their inhibitory effects on the production of PGE_2 in LPS-simulated RAW264.7 macrophages. The results showed that compounds 1, 2, 8, and 10-15 could reduce PGE_2 levels, to a certain extent.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9044 mL 14.5222 mL 29.0444 mL 58.0889 mL 72.6111 mL
    5 mM 0.5809 mL 2.9044 mL 5.8089 mL 11.6178 mL 14.5222 mL
    10 mM 0.2904 mL 1.4522 mL 2.9044 mL 5.8089 mL 7.2611 mL
    50 mM 0.0581 mL 0.2904 mL 0.5809 mL 1.1618 mL 1.4522 mL
    100 mM 0.029 mL 0.1452 mL 0.2904 mL 0.5809 mL 0.7261 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    2,3-二羟基-4-甲氧基苯甲酸; 2,3-Dihydroxy-4-methoxybenzoic acid CFN94481 3934-81-4 C8H8O5 = 184.1 5mg QQ客服:3257982914
    2-羟基-3,4-二甲氧基苯甲酸; 2-Hydroxy-3,4-dimethoxybenzoic acid CFN94461 5653-46-3 C9H10O5 = 198.17 5mg QQ客服:2159513211
    3,4-二甲氧基-2-羟基苯甲酸甲酯; Methyl 2-hydroxy-3,4-dimethoxybenzoate CFN95383 6395-23-9 C10H12O5 = 212.2 5mg QQ客服:1148253675
    没食子酸; 3,4,5-三羟基苯甲酸; Gallic acid CFN99624 149-91-7 C7H6O5 = 170.1 20mg QQ客服:1413575084
    没食子酸甲酯; Methyl gallate CFN93180 99-24-1 C8H8O5 = 184.15 20mg QQ客服:215959384
    丁香酸; Syringic acid CFN98884 530-57-4 C9H10O5 = 198.2 20mg QQ客服:1413575084
    丁香酸甲酯; Methyl syringate CFN97450 884-35-5 C10H12O5 = 212.2 20mg QQ客服:2932563308
    葡萄糖基丁香酸; Glucosyringic acid CFN98426 33228-65-8 C15H20O10 = 360.3 5mg QQ客服:2159513211
    灯盏花苷C; Erigeside C CFN99227 112667-09-1 C15H20O10 = 360.3 5mg QQ客服:1148253675
    拉帕醇; Tecomin CFN92856 31002-27-4 C15H20O9 = 344.3 5mg QQ客服:1148253675

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