5-Deoxystrigol

	产品编号	CFN89416
	CAS编号	151716-18-6
	分子式 = 分子量	C₁₉H₂₂O₅ = 330.37
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Sesquiterpenoids
	植物来源	The root exudate of Striga hermonthica (Del.) Benth.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

提供自定义包装

产品名称	产品编号	CAS编号	包装	QQ客服
5-Deoxystrigol	CFN89416	151716-18-6	1mg	QQ客服：3004468091
5-Deoxystrigol	CFN89416	151716-18-6	5mg	QQ客服：3004468091
5-Deoxystrigol	CFN89416	151716-18-6	10mg	QQ客服：3004468091
5-Deoxystrigol	CFN89416	151716-18-6	20mg	QQ客服：3004468091

存储与注意事项

1. 在您收到产品后请检查产品。如无问题，请将产品存入冰霜并且样品瓶保持密封，产品可以存放长达24个月（2-8摄氏度）。

2. 只要有可能，产品溶解后，您应该在同一天应用于您的实验。但是，如果您需要提前做预实验，或者需要全部溶解，我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。通常，这些可用于长达两周。使用前，打开样品瓶前，我们建议您将产品平衡至室温至少1小时。

3. 需要更多关于溶解度，使用和处理的建议？请发送电子邮件至：service@chemfaces.com

订购流程

1. 在线订购

请联系我们QQ客服

2. 电话订购

请拨打电话：
027-84237683 或 027-84237783

3. 邮件或传真订购

发送电子邮件到: manager@chemfaces.com 或
发送传真到：027-84254680

提供订购信息

为了方便客户的订购，请需要订购ChemFaces产品的客户，在下单的时候请提供下列信息，以供我们快速为您建立发货信息。

1. 产品编号（CAS No.或产品名称）

2. 发货地址

3. 联系方法 (联系人，电话）

4. 开票抬头 (如果需要发票的客户）

5. 发票地址（发货地址与发票地址不同）

发货时间

1. 付款方式为100%预付款客户，我们将在确认收到货款后当天或1-3个工作日发货。

2. 付款方式为月结的客户，我们承诺在收到订单后当天或1-3个工作日内发货。

3. 如果客户所需要的产品，需要重新生产，我们有权告知客户，交货时间需要延期。

ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Cornell University (USA)

Univerzita Karlova v Praze (Czech Republic)

Celltrion Chemical Research Institute (Korea)

Calcutta University (India)

University of Liège (Belgium)

Rio de Janeiro State University (Brazil)

Research Unit Molecular Epigenetics (MEG) (Germany)

FORTH-IMBB (Greece)

University Medical Center Mainz (Germany)

Nanjing University of Chinese Medicine (China)

Universite de Lille1 (France)

National Chung Hsing University (Taiwan)

University of Virginia (USA)

Universidade Federal de Goias (UFG) (Brazil)

More...

Description:

5-Deoxystrigol is a highly active Striga germination stimulant. It has a protective effect on D-galactosamine (D-GalN) induced mice acute liver injury and has a protective effect on CCl4 induced mice acute liver injury.

In vitro:

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4471-4476.

Mutation in sorghum LOW GERMINATION STIMULANT 1 alters strigolactones and causes Striga resistance.[Pubmed: 28396420]

Striga is a major biotic constraint to sorghum production in semiarid tropical Africa and Asia. Genetic resistance to this parasitic weed is the most economically feasible control measure. Mutant alleles at the LGS1 (LOW GERMINATION STIMULANT 1) locus drastically reduce Striga germination stimulant activity.
METHODS AND RESULTS:
We provide evidence that the responsible gene at LGS1 codes for an enzyme annotated as a sulfotransferase and show that functional loss of this gene results in a change of the dominant strigolactone (SL) in root exudates from 5-Deoxystrigol, a highly active Striga germination stimulant, to orobanchol, an SL with opposite stereochemistry. Orobanchol, although not previously reported in sorghum, functions in the multiple SL roles required for normal growth and environmental responsiveness but does not stimulate germination of Striga.
CONCLUSIONS:
This work describes the identification of a gene regulating Striga resistance and the underlying protective chemistry resulting from mutation.

In vivo:

CN 105287502 A[P]. 2016.

Application of 5-deoxystrigol in preparation of medicines for preventing and treating liver injury[Reference: WebLink]

METHODS AND RESULTS:
The inventor discloses 5-Deoxystrigol which has a protective effect on D-galactosamine (D-GalN) induced mice acute liver injury and has a protective effect on CCl4 induced mice acute liver injury.
CONCLUSIONS:
Thus, 5-Deoxystrigol can be used in preparation of medicines for preventing and treating liver injury or hepatitis and is disclosed for the first time. As the skeleton type belongs to a brand-new skeleton type and 5-Deoxystrigol has strong therapeutic activity on liver injury, 5-Deoxystrigol has outstanding substantial characteristics and obviously has prominent progress when used in anti-liver injury.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
GSK2334470; GSK2334470	CFN60273	1227911-45-6	C₂₅H₃₄N₈O = 462.59	5mg	QQ客服：3004468088
氧氟草苷D; Oxytroflavoside D	CFN95491	1391144-83-4	C₂₈H₃₀O₁₅ = 606.5	10mg	QQ客服：3004468091
4-甲氧基香豆素; 4-Methoxycoumarine	CFN94403	20280-81-3	C₁₀H₈O₃ = 176.17	20mg	QQ客服：3004468091
海罂粟碱; Glaucine	CFN90408	475-81-0	C₂₁H₂₅NO₄ = 355.43	20mg	QQ客服：3004468091

信息支持

公司简介
订购流程
付款方式
退换货政策

ChemFaces提供的产品仅用于科学研究使用，不用于诊断或治疗程序。

联系方式

电机：18607101326
传真：027-84254680
在线QQ: 3004468088
E-Mail：manager@chemfaces.com

湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房

ChemFaces为科学家，科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产。

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.0269 mL	15.1345 mL	30.2691 mL	60.5382 mL	75.6727 mL
5 mM	0.6054 mL	3.0269 mL	6.0538 mL	12.1076 mL	15.1345 mL
10 mM	0.3027 mL	1.5135 mL	3.0269 mL	6.0538 mL	7.5673 mL
50 mM	0.0605 mL	0.3027 mL	0.6054 mL	1.2108 mL	1.5135 mL
100 mM	0.0303 mL	0.1513 mL	0.3027 mL	0.6054 mL	0.7567 mL