红粉苔酸

Lecanoric acid

	产品编号	CFN98746
	CAS编号	480-56-8
	分子式 = 分子量	C₁₆H₁₄O₇ = 318.3
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Phenols
	植物来源	The herbs of Parmelia tinctorum Despr.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
红粉苔酸	CFN98746	480-56-8	1mg	QQ客服：215959384
红粉苔酸	CFN98746	480-56-8	5mg	QQ客服：215959384
红粉苔酸	CFN98746	480-56-8	10mg	QQ客服：215959384
红粉苔酸	CFN98746	480-56-8	20mg	QQ客服：215959384

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Osmania University (India)

University of Auckland (New Zealand)

Imperial College London (United Kingdom)

Yale University (USA)

University of Indonesia (Indonesia)

University of Helsinki (Finland)

Tokyo Woman's Christian University (Japan)

University of Illinois (USA)

St. Jude Children Research Hospital (USA)

Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)

Mahatma Gandhi University (India)

Universidad de Ciencias y Artes de Chiapas (Mexico)

University of Amsterdam (Netherlands)

The Ohio State University (USA)

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Description:

Lecanoric acid shows antioxidant activity with an IC50 value of 79-95 ug/ml, it at 100 ug/ml conc. shows high growth stimulating activity in terms of increased dry matter of biomass (56.08 mg) of L. casei.Lecanoric acid analogues antagonize several enzymic and cellular effects of the tumour promoter. Lecanoric acid analogues also inhibit prostaglandin synthetase and delayed-type hypersensitivity responses against sheep red blood cells in mice.

Targets:

GSK-3 | P450 (e.g. CYP17)

In vitro:

Biochem Biophys Res Commun. 1983 Feb 10;110(3):733-9.

Inhibition of histidine decarboxylase and tumour promoter-induced arachidonic acid release by lecanoric acid analogues.[Pubmed: 6404261]

METHODS AND RESULTS:
Lecanoric acid analogues containing benzanilide structure inhibited histidine decarboxylase and arachidonic acid release from the cell membrane phospholipids induced by a tumour promoter, 12-O-tetradecanoylphorbol-13-acetate. But they did not inhibit cellular binding of phorbol-12,13-dibutylate. Lecanoric acid analogues also inhibited prostaglandin synthetase and delayed-type hypersensitivity responses against sheep red blood cells in mice.
CONCLUSIONS:
Thus, Lecanoric acid analogues antagonized several enzymic and cellular effects of the tumour promoter.

J Food Sci Technol. 2014 Oct;51(10):2624-31.

Growth promoting effects of some lichen metabolites on probiotic bacteria.[Pubmed: 25328204]

METHODS AND RESULTS:
The lichen metabolites showed antioxidant activity with an IC50 values (μg/ml); Lecanoric acid 79-95, salazinic 88-108, atranorin 100-116 and consalazinic acid 119-125. As far as the growth promoting effects of lichen metabolites on L. casei is concerned, Lecanoric acid at 100 μg/ml conc. showed high growth stimulating activity in terms of increased dry matter of biomass (56.08 mg) of L. casei. Other lichen metabolites; salazinic acid, atranorin and consalazinic acid produced relatively less dry biomass 43.98 mg, 41.1 mg, 40.68 mg, respectively. However, standard antioxidants butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and Trolox after 36 h produced 39.04-47.81 mg dry biomass.
CONCLUSIONS:
At lower pH the growth promoting activity of lichen metabolites was found stable.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
2,4-二羟基-6-甲基苯甲酸甲酯; Methyl orsellinate	CFN98406	3187-58-4	C₉H₁₀O₄ = 182.2	5mg	QQ客服：3257982914
红粉苔酸; Lecanoric acid	CFN98746	480-56-8	C₁₆H₁₄O₇ = 318.3	5mg	QQ客服：3257982914
扁枝衣二酸; Evernic acid	CFN70402	537-09-7	C₁₇H₁₆O₇ = 332.3	5mg	QQ客服：215959384
石耳酸; Gyrophoric acid	CFN98919	548-89-0	C₂₄H₂₀O₁₀ = 468.4	5mg	QQ客服：1457312923
2,4-二羟基-3,6-二甲基苯甲酸甲酯; Atraric acid	CFN98703	4707-47-5	C₁₀H₁₂O₄ = 196.2	20mg	QQ客服：215959384
巴美灵; Atranorin	CFN98728	479-20-9	C₁₉H₁₈O₈ = 374.4	10mg	QQ客服：3257982914

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.1417 mL	15.7085 mL	31.4169 mL	62.8338 mL	78.5423 mL
5 mM	0.6283 mL	3.1417 mL	6.2834 mL	12.5668 mL	15.7085 mL
10 mM	0.3142 mL	1.5708 mL	3.1417 mL	6.2834 mL	7.8542 mL
50 mM	0.0628 mL	0.3142 mL	0.6283 mL	1.2567 mL	1.5708 mL
100 mM	0.0314 mL	0.1571 mL	0.3142 mL	0.6283 mL	0.7854 mL