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  • 5-苄氧基吲哚-3-乙醛酰胺

    Indole-3-glyoxylamide

    5-苄氧基吲哚-3-乙醛酰胺
    产品编号 CFN96487
    CAS编号 5548-10-7
    分子式 = 分子量 C10H8N2O2 = 188.18
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Alkaloids
    植物来源
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    5-苄氧基吲哚-3-乙醛酰胺 CFN96487 5548-10-7 1mg QQ客服:2056216494
    5-苄氧基吲哚-3-乙醛酰胺 CFN96487 5548-10-7 5mg QQ客服:2056216494
    5-苄氧基吲哚-3-乙醛酰胺 CFN96487 5548-10-7 10mg QQ客服:2056216494
    5-苄氧基吲哚-3-乙醛酰胺 CFN96487 5548-10-7 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Nanjing University of Chinese Medicine (China)
  • Semmelweis Unicersity (Hungary)
  • CSIRO - Agriculture Flagship (Australia)
  • Seoul National University of Science and Technology (Korea)
  • Universidade Católica Portuguesa (Portugal)
  • Lund University (Sweden)
  • Universiti Malaysia Pahang (Malaysia)
  • University of Bordeaux (France)
  • Siksha O Anusandhan University (India)
  • MTT Agrifood Research Finland (Finland)
  • Osmania University (India)
  • Georgia Institute of Technology (USA)
  • Universidad de Ciencias y Artes de Chiapas (Mexico)
  • Celltrion Chemical Research Institute (Korea)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Front Plant Sci.2022, 13: 905275.
  • Phytomedicine2022, 104:154337.
  • Molecules.2018, 23(11):E2837
  • Heliyon.2022, 8(12):e12031.
  • Evid Based Complement Alternat Med.2021, 8855980.
  • Turkish Journal of Pharmaceutical Sciences2022, DOI: 10.4274
  • Metabolites.2023, 13(5):625.
  • Molecules.2021, 26(9):2765.
  • Nutraceutical Research . 2021, 19(1),p90-105.
  • J Clin Med.2019, 8(10):E1664
  • Srinagarind Medical Journal2019, 34(1)
  • Int J Mol Sci.2022, 23(23):14826.
  • Br J Pharmacol.2020, 10.1111
  • J Appl Pharm Sci.2022, 12(04):044-053
  • J Appl Biol Chem2023, 66:455−461
  • Acta Pharm Sin B.2015, 5(4):323-9.
  • PLoS One.2017, 12(8):e0181191
  • Front Aging Neurosci.2018, 10:269
  • Toxins (Basel).2020, 12(4):210.
  • Journal of Phytopathology2021, 169,Issue11-12.
  • Food Addit Contam Part A Chem Anal Control Expo Risk Assess.2020, 37(9):1437-1448.
  • J Pharmaceutical and Biomedical Analysis2022, 114631.
  • Food Research2022, 6(6): 30-38.
  • ...
  • 生物活性
    Description: Indole-3-glyoxylamides are an attractive lead series for continuing development as potential therapeutic agents against prion disease. A number of Indole-3-glyoxylamides have previously been reported as tubulin polymerization inhibitors, exert a cytotoxic effect against multiple cancer cell lines.
    Targets: Antifection
    In vitro:
    J Nat Prod. 2011 Apr 25;74(4):888-92.
    Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian Didemnum sp.[Pubmed: 21348447 ]

    METHODS AND RESULTS:
    Two new indole spermidine alkaloids, didemnidines A (1) and B (2), have been isolated from the New Zealand ascidian Didemnum sp. The structures of the metabolites, determined by analysis of 2D NMR spectra and confirmed via synthesis, embody an Indole-3-glyoxylamide moiety linked to the N(1) position of spermidine, the latter motif being particularly rare among marine natural products.
    CONCLUSIONS:
    Didemnidine B and a synthetic precursor exhibited mild in vitro growth inhibition of Plasmodium falciparum with IC(50)'s of 15 and 8.4 μM, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.3141 mL 26.5703 mL 53.1406 mL 106.2812 mL 132.8515 mL
    5 mM 1.0628 mL 5.3141 mL 10.6281 mL 21.2562 mL 26.5703 mL
    10 mM 0.5314 mL 2.657 mL 5.3141 mL 10.6281 mL 13.2852 mL
    50 mM 0.1063 mL 0.5314 mL 1.0628 mL 2.1256 mL 2.657 mL
    100 mM 0.0531 mL 0.2657 mL 0.5314 mL 1.0628 mL 1.3285 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    圆锥定C; Paniculidine C CFN97554 97399-95-6 C13H17NO = 203.3 5mg QQ客服:3257982914
    吲哚-3-丙烯酸甲酯; Indole-3-acrylic acid methyl ester CFN99899 19626-92-7 C12H11NO2 = 201.2 5mg QQ客服:1413575084
    3-吲哚乙酸; Indolelactic acid CFN95263 1821-52-9 C11H11NO3 = 205.2 20mg QQ客服:1413575084
    3-咔唑羧酸甲酯; Methyl 3-carbazolecarboxylate CFN97559 97931-41-4 C14H11NO2 = 225.2 5mg QQ客服:3257982914
    吲哚-3-甲酸; 1H-Indole-3-carboxylic acid CFN97256 771-50-6 C9H7NO2 = 161.2 20mg QQ客服:3257982914
    吲哚-3-甲酸甲酯; Methyl 3-indolecarboxylate CFN97515 942-24-5 C10H9NO2 = 175.2 20mg QQ客服:1457312923
    2-(1H-Indole-3-carboxamido)benzoic acid; 2-(1H-Indole-3-carboxamido)benzoic acid CFN96192 171817-95-1 C16H12N2O3 = 280.3 5mg QQ客服:1413575084
    Cephalandole B; Cephalandole B CFN91534 915315-44-5 C17H14N2O3 = 294.3 5mg QQ客服:3257982914
    5-苄氧基吲哚-3-乙醛酰胺; Indole-3-glyoxylamide CFN96487 5548-10-7 C10H8N2O2 = 188.18 5mg QQ客服:1457312923
    圆锥定A; Paniculidine A CFN97552 97399-93-4 C14H17NO2 = 231.3 5mg QQ客服:3257982914

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