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  • Delaminomycin A

    Delaminomycin A

    Delaminomycin A
    产品编号 CFN00113
    CAS编号 149779-38-4
    分子式 = 分子量 C29H43NO6 = 501.66
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 From Streptomyces albulus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Delaminomycin A CFN00113 149779-38-4 1mg QQ客服:1457312923
    Delaminomycin A CFN00113 149779-38-4 5mg QQ客服:1457312923
    Delaminomycin A CFN00113 149779-38-4 10mg QQ客服:1457312923
    Delaminomycin A CFN00113 149779-38-4 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Utah State University (USA)
  • Sri Ramachandra University (India)
  • Florida A&M University (USA)
  • Monash University Sunway Campus (Malaysia)
  • Harvard University (USA)
  • University of Leipzig (Germany)
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • University of Eastern Finland (Finland)
  • Semmelweis Unicersity (Hungary)
  • Hamdard University (India)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • Wageningen University (Netherlands)
  • Sant Gadge Baba Amravati University (India)
  • Utrecht University (Netherlands)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Antioxidants (Basel).2020, 9(4):326.
  • Process Biochemistry2019, 85:106-115
  • LWT2021, 150:112021.
  • Food Funct.2022, 13(14):7638-7649.
  • J Nat Prod.2022, doi: 10.1021
  • Food and Chemical Toxicology2020, 111221
  • J Neuroinflammation.2020, 17(1):75.
  • Environ Toxicol.2022, 37(3):514-526.
  • Molecules.2020, 25(7):1625.
  • J. Soc. Cosmet. Sci. Korea2016, 163-171
  • J Sep Sci.2018, 41(9):1938-1946
  • Int J Mol Sci.2019, 20(14):E3538
  • J Biochem Mol Toxicol.2021, 35(5):e22731.
  • International J of Green Pharmacy2019, 13(3)
  • Planta Med.2019, 85(4):347-355
  • Integr Med Res.2021, 10(3):100723.
  • J Adv Res.2019, 17:85-94
  • Nat Prod Sci.2018, 24(2):109-114
  • Journal of Phytopathology2021, 169,Issue11-12.
  • Horticulturae2021, 7(1),5.
  • Biomed Pharmacother.2019, 116:108987
  • Molecules.2017, 22(11)
  • Biochem Biophys Res Commun.2017, 482(4):1095-1101
  • ...
  • 生物活性
    Description: Delaminomycin A is an immunomodulator, it is a cell adhesion inhibitor and extracellular matrix receptor antagonist. Delaminomycin A is active against gram-positive bacteria.
    Targets: Immunology & Inflammation related
    In vitro:
    J Antibiot (Tokyo). 1993 Jul;46(7):1156-62.
    Delaminomycins, novel extracellular matrix receptor antagonist. IV. Structure-activity relationships of delaminomycins and derivatives.[Pubmed: 8360111]
    Delaminomycin A, Delaminomycin B, Delaminomycin C and their derivatives were prepared and investigated biological activities of them.
    METHODS AND RESULTS:
    Among these compounds, spiro compounds (A2, B2 and C2) showed stronger inhibitory activity than natural products (A1, B1 and C1) on B16 melanoma cells adhesion assay and Con A-induced proliferation of murine splenic lymphocytes assay. In MLCR and antimicrobial assay, however, A1, B1 and C1 showed more potent inhibitory activity than spiro compounds (A2, B2 and C2). On the other hand, as to C-5' substituents of pyrrolidine ring, the order of inhibitory activity was R = OH > R = OCH3 > R = H on Con A-induced proliferation of murine splenic lymphocytes assay. In MLCR and antimicrobial assay, however, the order of inhibitory activities were R = H > R = OCH3 > R = OH.
    CONCLUSIONS:
    Inhibitory activities of A4 which was lacked pyrrolidine ring were reduced on B16 melanoma cells adhesion assay and on cytotoxicity against tumor cells in vitro in comparison with those of A1.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.9934 mL 9.9669 mL 19.9338 mL 39.8676 mL 49.8345 mL
    5 mM 0.3987 mL 1.9934 mL 3.9868 mL 7.9735 mL 9.9669 mL
    10 mM 0.1993 mL 0.9967 mL 1.9934 mL 3.9868 mL 4.9835 mL
    50 mM 0.0399 mL 0.1993 mL 0.3987 mL 0.7974 mL 0.9967 mL
    100 mM 0.0199 mL 0.0997 mL 0.1993 mL 0.3987 mL 0.4983 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    抗菌素 2158; Antibiotic 2158 CFN00105 182320-34-9 C33H45NO4 = 519.72 5mg QQ客服:2056216494
    抗菌素 AB 4015B; Antibiotic AB 4015B CFN00106 162857-79-6 C26H39NO3 = 413.6 5mg QQ客服:2159513211
    抗菌素 AB 4063B; Antibiotic AB 4063B CFN00107 160041-33-8 C26H39NO3 = 413.6 5mg QQ客服:3257982914
    抗菌素 PF 1052; Antibiotic PF 1052 CFN00108 147317-15-5 C26H39NO4 = 429.60 5mg QQ客服:2056216494
    Delaminomycin A; Delaminomycin A CFN00113 149779-38-4 C29H43NO6 = 501.66 5mg QQ客服:1413575084
    伊快霉素; Equisetin CFN00115 57749-43-6 C22H31NO4 = 373.49 5mg QQ客服:2159513211
    Oteromycin; Oteromycin CFN00129 170591-45-4 C32H41NO3 = 487.68 5mg QQ客服:2056216494
    抗菌素 ZG 1494alpha; Antibiotic ZG 1494alpha CFN00130 182320-33-8 C32H43NO4 = 505.70 5mg QQ客服:215959384
    Vermisporin; Vermisporin CFN00143 122301-98-8 C25H37NO4 = 415.57 5mg QQ客服:215959384
    Zopfiellamide A; Zopfiellamide A CFN00145 478945-64-1 C25H35NO6 = 445.55 5mg QQ客服:1457312923

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